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Protein

Phosphoethanolamine transferase OpgE

Gene

opgE

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalyzes the addition of a phosphoethanolamine moiety to the osmoregulated periplasmic glucan (OPG) backbone.1 Publication

Pathwayi: osmoregulated periplasmic glucan (OPG) biosynthesis

This protein is involved in the pathway osmoregulated periplasmic glucan (OPG) biosynthesis, which is part of Glycan metabolism.1 Publication
View all proteins of this organism that are known to be involved in the pathway osmoregulated periplasmic glucan (OPG) biosynthesis and in Glycan metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase

Enzyme and pathway databases

BioCyciEcoCyc:G6418-MONOMER
MetaCyc:G6418-MONOMER
UniPathwayiUPA00637

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoethanolamine transferase OpgE (EC:2.7.-.-)
Gene namesi
Name:opgE
Synonyms:ybiP
Ordered Locus Names:b0815, JW0800
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13321 opgE

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 33PeriplasmicSequence analysisAdd BLAST33
Transmembranei34 – 54HelicalSequence analysisAdd BLAST21
Topological domaini55 – 62CytoplasmicSequence analysis8
Transmembranei63 – 83HelicalSequence analysisAdd BLAST21
Topological domaini84 – 106PeriplasmicSequence analysisAdd BLAST23
Transmembranei107 – 127HelicalSequence analysisAdd BLAST21
Topological domaini128 – 146CytoplasmicSequence analysisAdd BLAST19
Transmembranei147 – 167HelicalSequence analysisAdd BLAST21
Topological domaini168 – 527PeriplasmicSequence analysisAdd BLAST360

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002091451 – 527Phosphoethanolamine transferase OpgEAdd BLAST527

Proteomic databases

PaxDbiP75785
PRIDEiP75785

Interactioni

Protein-protein interaction databases

BioGridi4259975, 3 interactors
IntActiP75785, 3 interactors
STRINGi316385.ECDH10B_0883

Structurei

3D structure databases

ProteinModelPortaliP75785
SMRiP75785
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4108I6E Bacteria
COG2194 LUCA
HOGENOMiHOG000118161
OMAiEVQYLAH
PhylomeDBiP75785

Family and domain databases

Gene3Di3.40.720.10, 1 hit
InterProiView protein in InterPro
IPR017849 Alkaline_Pase-like_a/b/a
IPR017850 Alkaline_phosphatase_core_sf
IPR000917 Sulfatase_N
PfamiView protein in Pfam
PF00884 Sulfatase, 1 hit
SUPFAMiSSF53649 SSF53649, 1 hit

Sequencei

Sequence statusi: Complete.

P75785-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLTLKESLV TRSRVFSPWT AFYFLQSLLI NLGLGYPFSL LYTAAFTAIL
60 70 80 90 100
LLLWRTLPRV QKVLVGVSSL VAACYFPFAQ AYGAPNFNTL LALHSTNMEE
110 120 130 140 150
STEILTIFPW YSYLVGLFIF ALGVIAIRRK KENEKARWNT FDSLCLVFSV
160 170 180 190 200
ATFFVAPVQN LAWGGVFKLK DTGYPVFRFA KDVIVNNNEV IEEQERMAKL
210 220 230 240 250
SGMKDTWTVT AVKPKYQTYV VVIGESARRD ALGAFGGHWD NTPFASSVNG
260 270 280 290 300
LIFADYIAAS GSTQKSLGLT LNRVVDGKPQ FQDNFVTLAN RAGFQTWWFS
310 320 330 340 350
NQGQIGEYDT AIASIAKRAD EVYFLKEGNF EADKNTKDEA LLDMTAQVLA
360 370 380 390 400
QEHSQPQLIV LHLMGSHPQA CDRTQGKYET FVQSKETSCY LYTMTQTDDL
410 420 430 440 450
LRKLYDQLRN SGSSFSLVYF SDHGLAFKER GKDVQYLAHD DKYQQNFQVP
460 470 480 490 500
FMVISSDDKA HRVIKARRSA NDFLGFFSQW TGIKAKEINI KYPFISEKKA
510 520
GPIYITNFQL QKVDYNHLGT DIFDPKP
Length:527
Mass (Da):59,706
Last modified:February 1, 1997 - v1
Checksum:i7069D6C1A5503A2A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC73902.1
AP009048 Genomic DNA Translation: BAA35487.1
PIRiG64818
RefSeqiNP_415336.1, NC_000913.3
WP_001054678.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC73902; AAC73902; b0815
BAA35487; BAA35487; BAA35487
GeneIDi945360
KEGGiecj:JW0800
eco:b0815
PATRICifig|1411691.4.peg.1463

Similar proteinsi

Entry informationi

Entry nameiOPGE_ECOLI
AccessioniPrimary (citable) accession number: P75785
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: March 28, 2018
This is version 121 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health