Reviewed, UniProtKB/Swiss-Prot P75747 (ABRB_ECOLI)

Names and origin

Protein names

Recommended name:
    Protein abrB
Alternative name(s):
    AidB regulator

Gene names

Name:	abrB
Synonyms:	ybgN
Ordered Locus Names:	b0715, JW5097
ORF Names:	ECK0704

Organism

Escherichia coli (strain K12) [Complete proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	348 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Seems to be involved in the regulation of aidB. Ref.4
Subcellular location	Cell inner membrane; Multi-pass membrane protein.
Sequence similarities	Belongs to the abrB family.

Ontologies

Keywords
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 348	348	Protein abrB		PRO_0000064432
Regions
	Transmembrane	20 – 40	21	Potential
	Transmembrane	59 – 79	21	Potential
	Transmembrane	83 – 103	21	Potential
	Transmembrane	138 – 158	21	Potential
	Transmembrane	173 – 193	21	Potential
	Transmembrane	196 – 216	21	Potential
	Transmembrane	221 – 241	21	Potential
	Transmembrane	259 – 279	21	Potential
	Transmembrane	288 – 308	21	Potential
	Transmembrane	315 – 335	21	Potential

Sequences

	Sequence		Length	Mass (Da)
	P75747-1 [UniParc]. Last modified December 1, 2000. Version 2. Checksum: 9A667EA6321B0B8A	FASTA	348	36,884
	10 20 30 40 50 60 MPVLQWGMLC VLSLLLSIGF LAVHLPAALL LGPMIAGIIF SMRGITLQLP RSAFLAAQAI 70 80 90 100 110 120 LGCMIAQNLT GSILTTLAVN WPIVLAILLV TLLSSAIVGW LLVRYSSLPG NTGAWGSSPG 130 140 150 160 170 180 GAAAMVAMAQ DYGADIRLVA FMQYLRVLFV AGAAVLVTRM MLGDNAEAVN QHIVWFPPVS 190 200 210 220 230 240 INLLLTILLA VVAGTVGCLL RLPSGTMLIP MLAGAVLQSG QLITIELPEW LLAMAYMAIG 250 260 270 280 290 300 WRIGLGFDKQ ILLRALRPLP QILLSIFALL AICAGMAWGL TRFMHIDFMT AYLATSPGGL 310 320 330 340 DTVAVIAAGS NADMALIMAM QTLRLFSILL TGPAIARFIS TYAPKRSA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map." Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K., Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S., Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K. , Mori H., Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G., Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M., Horiuchi T. DNA Res. 3:137-155(1996) [PubMed: 8905232] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[2]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[4]	"Induction of the Escherichia coli aidB gene under oxygen-limiting conditions requires a functional rpoS (katF) gene." Volkert M.R., Hajec L.I., Matijasevic Z., Fang F.C., Prince R. J. Bacteriol. 176:7638-7645(1994) [PubMed: 8002588] [Abstract] Cited for: POSSIBLE FUNCTION.
[5]	"Global topology analysis of the Escherichia coli inner membrane proteome." Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G. Science 308:1321-1323(2005) [PubMed: 15919996] [Abstract] Cited for: SUBCELLULAR LOCATION. Strain: K12 / MG1655 / ATCC 47076.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U00096 Genomic DNA. Translation: AAC73809.1. AP009048 Genomic DNA. Translation: BAA35379.1.
PIR	B64807.
RefSeq	AP_001353.1. NP_415243.4.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	P75747.
Genome annotation databases
GeneID	945321.
GenomeReviews	Gene locus JW5097 in contig AP009048_GR. Gene locus b0715 in contig U00096_GR.
KEGG	ecj:JW5097. eco:b0715.
Organism-specific databases
EchoBASE	EB3094.
EcoGene	EG13310. abrB.
CMR	Search...
Phylogenomic databases
HOGENOM	P75747.
OMA	PGGASAM
Enzyme and pathway databases
BioCyc	EcoCyc:G6384-MON. ECOL168927:B0715-MON.
Gene expression databases
Genevestigator	P75747.
Family and domain databases
InterPro	IPR017516. AbrB_dup. IPR007820. Put_NH3_mOase. [Graphical view]
Pfam	PF05145. AmoA. 1 hit. [Graphical view]
TIGRFAMs	TIGR03082. Gneg_AbrB_dup. 2 hits.
ProtoNet	Search...

Entry information

Entry name

ABRB_ECOLI

Accession

Primary (citable) accession number: P75747

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	December 1, 2000
Last modified:	November 24, 2009
This is version 65 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)