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Protein

Protein AbrB

Gene

abrB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Seems to be involved in the regulation of AidB.

GO - Biological processi

  • positive regulation of gene expression Source: EcoCyc
Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:G6384-MONOMER.
ECOL316407:JW5097-MONOMER.
RETL1328306-WGS:GSTH-2848-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein AbrB
Alternative name(s):
AidB regulator
Gene namesi
Name:abrB
Synonyms:ybgN
Ordered Locus Names:b0715, JW5097
ORF Names:ECK0704
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13310. abrB.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei20 – 4021HelicalSequence analysisAdd
BLAST
Transmembranei59 – 7921HelicalSequence analysisAdd
BLAST
Transmembranei83 – 10321HelicalSequence analysisAdd
BLAST
Transmembranei138 – 15821HelicalSequence analysisAdd
BLAST
Transmembranei173 – 19321HelicalSequence analysisAdd
BLAST
Transmembranei196 – 21621HelicalSequence analysisAdd
BLAST
Transmembranei221 – 24121HelicalSequence analysisAdd
BLAST
Transmembranei259 – 27921HelicalSequence analysisAdd
BLAST
Transmembranei288 – 30821HelicalSequence analysisAdd
BLAST
Transmembranei315 – 33521HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 348348Protein AbrBPRO_0000064432Add
BLAST

Proteomic databases

PaxDbiP75747.

Interactioni

Protein-protein interaction databases

BioGridi4259923. 1 interaction.
STRINGi511145.b0715.

Structurei

3D structure databases

ProteinModelPortaliP75747.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the AbrB family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4108KK1. Bacteria.
COG3180. LUCA.
HOGENOMiHOG000076013.
InParanoidiP75747.
KOiK07120.
OMAiLLGPMIV.
PhylomeDBiP75747.

Family and domain databases

InterProiIPR017516. AbrB_dup.
IPR007820. AbrB_fam.
[Graphical view]
PfamiPF05145. AmoA. 1 hit.
[Graphical view]
PIRSFiPIRSF038991. Protein_AbrB. 1 hit.
TIGRFAMsiTIGR03082. Gneg_AbrB_dup. 2 hits.

Sequencei

Sequence statusi: Complete.

P75747-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPVLQWGMLC VLSLLLSIGF LAVHLPAALL LGPMIAGIIF SMRGITLQLP
60 70 80 90 100
RSAFLAAQAI LGCMIAQNLT GSILTTLAVN WPIVLAILLV TLLSSAIVGW
110 120 130 140 150
LLVRYSSLPG NTGAWGSSPG GAAAMVAMAQ DYGADIRLVA FMQYLRVLFV
160 170 180 190 200
AGAAVLVTRM MLGDNAEAVN QHIVWFPPVS INLLLTILLA VVAGTVGCLL
210 220 230 240 250
RLPSGTMLIP MLAGAVLQSG QLITIELPEW LLAMAYMAIG WRIGLGFDKQ
260 270 280 290 300
ILLRALRPLP QILLSIFALL AICAGMAWGL TRFMHIDFMT AYLATSPGGL
310 320 330 340
DTVAVIAAGS NADMALIMAM QTLRLFSILL TGPAIARFIS TYAPKRSA
Length:348
Mass (Da):36,884
Last modified:December 1, 2000 - v2
Checksum:i9A667EA6321B0B8A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC73809.2.
AP009048 Genomic DNA. Translation: BAA35379.2.
PIRiB64807.
RefSeqiNP_415243.4. NC_000913.3.
WP_001336221.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73809; AAC73809; b0715.
BAA35379; BAA35379; BAA35379.
GeneIDi945321.
KEGGiecj:JW5097.
eco:b0715.
PATRICi32116625. VBIEscCol129921_0745.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC73809.2.
AP009048 Genomic DNA. Translation: BAA35379.2.
PIRiB64807.
RefSeqiNP_415243.4. NC_000913.3.
WP_001336221.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP75747.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259923. 1 interaction.
STRINGi511145.b0715.

Proteomic databases

PaxDbiP75747.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73809; AAC73809; b0715.
BAA35379; BAA35379; BAA35379.
GeneIDi945321.
KEGGiecj:JW5097.
eco:b0715.
PATRICi32116625. VBIEscCol129921_0745.

Organism-specific databases

EchoBASEiEB3094.
EcoGeneiEG13310. abrB.

Phylogenomic databases

eggNOGiENOG4108KK1. Bacteria.
COG3180. LUCA.
HOGENOMiHOG000076013.
InParanoidiP75747.
KOiK07120.
OMAiLLGPMIV.
PhylomeDBiP75747.

Enzyme and pathway databases

BioCyciEcoCyc:G6384-MONOMER.
ECOL316407:JW5097-MONOMER.
RETL1328306-WGS:GSTH-2848-MONOMER.

Miscellaneous databases

PROiP75747.

Family and domain databases

InterProiIPR017516. AbrB_dup.
IPR007820. AbrB_fam.
[Graphical view]
PfamiPF05145. AmoA. 1 hit.
[Graphical view]
PIRSFiPIRSF038991. Protein_AbrB. 1 hit.
TIGRFAMsiTIGR03082. Gneg_AbrB_dup. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiABRB_ECOLI
AccessioniPrimary (citable) accession number: P75747
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: December 1, 2000
Last modified: September 7, 2016
This is version 109 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.