Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Esterase YbfF

Gene

ybfF

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Displays esterase activity toward palmitoyl-CoA, malonyl-CoA and pNP-butyrate.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei89By similarity1
Active sitei234By similarity1

GO - Molecular functioni

  • carboxylic ester hydrolase activity Source: EcoCyc
  • thiolester hydrolase activity Source: EcoCyc
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Serine esterase

Enzyme and pathway databases

BioCyciEcoCyc:EG11776-MONOMER.
ECOL316407:JW0673-MONOMER.
BRENDAi3.1.2.2. 2026.

Protein family/group databases

ESTHERiecoli-ybff. 6_AlphaBeta_hydrolase.

Names & Taxonomyi

Protein namesi
Recommended name:
Esterase YbfF (EC:3.1.-.-)
Gene namesi
Name:ybfF
Ordered Locus Names:b0686, JW0673
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11776. ybfF.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: EcoCyc
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002070811 – 254Esterase YbfFAdd BLAST254

Proteomic databases

EPDiP75736.
PaxDbiP75736.
PRIDEiP75736.

Interactioni

Protein-protein interaction databases

BioGridi4261906. 3 interactors.
IntActiP75736. 4 interactors.
STRINGi511145.b0686.

Structurei

Secondary structure

1254
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi5 – 8Combined sources4
Beta strandi19 – 22Combined sources4
Turni29 – 32Combined sources4
Helixi33 – 39Combined sources7
Turni40 – 42Combined sources3
Beta strandi45 – 48Combined sources4
Helixi64 – 78Combined sources15
Beta strandi83 – 88Combined sources6
Helixi90 – 101Combined sources12
Helixi103 – 105Combined sources3
Beta strandi106 – 113Combined sources8
Helixi125 – 136Combined sources12
Helixi142 – 149Combined sources8
Turni150 – 152Combined sources3
Helixi156 – 163Combined sources8
Beta strandi170 – 173Combined sources4
Helixi175 – 180Combined sources6
Helixi182 – 186Combined sources5
Beta strandi198 – 201Combined sources4
Helixi211 – 213Combined sources3
Helixi214 – 220Combined sources7
Beta strandi224 – 226Combined sources3
Helixi236 – 239Combined sources4
Helixi241 – 253Combined sources13

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3BF7X-ray1.10A/B1-254[»]
3BF8X-ray1.68A/B1-254[»]
ProteinModelPortaliP75736.
SMRiP75736.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP75736.

Family & Domainsi

Sequence similaritiesi

Belongs to the DmpD/TodF/XylF esterase family.Curated

Phylogenomic databases

eggNOGiENOG4105EV9. Bacteria.
COG0596. LUCA.
HOGENOMiHOG000028067.
InParanoidiP75736.
KOiK01175.
OMAiFPYEPGE.
PhylomeDBiP75736.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR000073. AB_hydrolase_1.
[Graphical view]
PfamiPF12697. Abhydrolase_6. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.

Sequencei

Sequence statusi: Complete.

P75736-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLNIRAQTA QNQHNNSPIV LVHGLFGSLD NLGVLARDLV NDHNIIQVDM
60 70 80 90 100
RNHGLSPRDP VMNYPAMAQD LVDTLDAQQI DKATFIGHSM GGKAVMALTA
110 120 130 140 150
LASDRIDKLV AIDIAPVDYH VRRHDEIFAA INAVSESDAQ TRQQAAAIMR
160 170 180 190 200
QHLNEEGVIQ FLLKSFVDGE WRFNVPVLWD QYPHIVGWEK IPAWDHPALF
210 220 230 240 250
IPGGNSPYVS EQYRDDLLAQ FPQARAHVIA GAGHWVHAEK PDAVLRAIRR

YLND
Length:254
Mass (Da):28,437
Last modified:February 1, 1997 - v1
Checksum:i8B2F6E28713D9B8A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC73780.1.
AP009048 Genomic DNA. Translation: BAA35335.1.
PIRiE64803.
RefSeqiNP_415212.1. NC_000913.3.
WP_000773288.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73780; AAC73780; b0686.
BAA35335; BAA35335; BAA35335.
GeneIDi945288.
KEGGiecj:JW0673.
eco:b0686.
PATRICi32116565. VBIEscCol129921_0715.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC73780.1.
AP009048 Genomic DNA. Translation: BAA35335.1.
PIRiE64803.
RefSeqiNP_415212.1. NC_000913.3.
WP_000773288.1. NZ_LN832404.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3BF7X-ray1.10A/B1-254[»]
3BF8X-ray1.68A/B1-254[»]
ProteinModelPortaliP75736.
SMRiP75736.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261906. 3 interactors.
IntActiP75736. 4 interactors.
STRINGi511145.b0686.

Protein family/group databases

ESTHERiecoli-ybff. 6_AlphaBeta_hydrolase.

Proteomic databases

EPDiP75736.
PaxDbiP75736.
PRIDEiP75736.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73780; AAC73780; b0686.
BAA35335; BAA35335; BAA35335.
GeneIDi945288.
KEGGiecj:JW0673.
eco:b0686.
PATRICi32116565. VBIEscCol129921_0715.

Organism-specific databases

EchoBASEiEB1725.
EcoGeneiEG11776. ybfF.

Phylogenomic databases

eggNOGiENOG4105EV9. Bacteria.
COG0596. LUCA.
HOGENOMiHOG000028067.
InParanoidiP75736.
KOiK01175.
OMAiFPYEPGE.
PhylomeDBiP75736.

Enzyme and pathway databases

BioCyciEcoCyc:EG11776-MONOMER.
ECOL316407:JW0673-MONOMER.
BRENDAi3.1.2.2. 2026.

Miscellaneous databases

EvolutionaryTraceiP75736.
PROiP75736.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR000073. AB_hydrolase_1.
[Graphical view]
PfamiPF12697. Abhydrolase_6. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYBFF_ECOLI
AccessioniPrimary (citable) accession number: P75736
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: November 2, 2016
This is version 116 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.