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Protein

Esterase YbfF

Gene

ybfF

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Displays esterase activity toward palmitoyl-CoA, malonyl-CoA and pNP-butyrate.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei89By similarity1
Active sitei234By similarity1

GO - Molecular functioni

  • carboxylic ester hydrolase activity Source: EcoCyc
  • thiolester hydrolase activity Source: EcoCyc

Keywordsi

Molecular functionHydrolase, Serine esterase

Enzyme and pathway databases

BioCyciEcoCyc:EG11776-MONOMER
BRENDAi3.1.2.2 2026

Protein family/group databases

ESTHERiecoli-ybff ABHD11-Acetyl_transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Esterase YbfF (EC:3.1.-.-)
Gene namesi
Name:ybfF
Ordered Locus Names:b0686, JW0673
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11776 ybfF

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: EcoCyc

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002070811 – 254Esterase YbfFAdd BLAST254

Proteomic databases

EPDiP75736
PaxDbiP75736
PRIDEiP75736

Interactioni

Protein-protein interaction databases

BioGridi4261906, 7 interactors
IntActiP75736, 4 interactors
STRINGi316385.ECDH10B_0751

Structurei

Secondary structure

1254
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi5 – 8Combined sources4
Beta strandi19 – 22Combined sources4
Turni29 – 32Combined sources4
Helixi33 – 39Combined sources7
Turni40 – 42Combined sources3
Beta strandi45 – 48Combined sources4
Helixi64 – 78Combined sources15
Beta strandi83 – 88Combined sources6
Helixi90 – 101Combined sources12
Helixi103 – 105Combined sources3
Beta strandi106 – 113Combined sources8
Helixi125 – 136Combined sources12
Helixi142 – 149Combined sources8
Turni150 – 152Combined sources3
Helixi156 – 163Combined sources8
Beta strandi170 – 173Combined sources4
Helixi175 – 180Combined sources6
Helixi182 – 186Combined sources5
Beta strandi198 – 201Combined sources4
Helixi211 – 213Combined sources3
Helixi214 – 220Combined sources7
Beta strandi224 – 226Combined sources3
Helixi236 – 239Combined sources4
Helixi241 – 253Combined sources13

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3BF7X-ray1.10A/B1-254[»]
3BF8X-ray1.68A/B1-254[»]
ProteinModelPortaliP75736
SMRiP75736
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP75736

Family & Domainsi

Sequence similaritiesi

Belongs to the DmpD/TodF/XylF esterase family.Curated

Phylogenomic databases

eggNOGiENOG4105EV9 Bacteria
COG0596 LUCA
HOGENOMiHOG000028067
InParanoidiP75736
KOiK01175
OMAiHWLHAEN
PhylomeDBiP75736

Family and domain databases

Gene3Di3.40.50.1820, 1 hit
InterProiView protein in InterPro
IPR029058 AB_hydrolase
IPR000073 AB_hydrolase_1
PfamiView protein in Pfam
PF12697 Abhydrolase_6, 1 hit
SUPFAMiSSF53474 SSF53474, 1 hit

Sequencei

Sequence statusi: Complete.

P75736-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLNIRAQTA QNQHNNSPIV LVHGLFGSLD NLGVLARDLV NDHNIIQVDM
60 70 80 90 100
RNHGLSPRDP VMNYPAMAQD LVDTLDAQQI DKATFIGHSM GGKAVMALTA
110 120 130 140 150
LASDRIDKLV AIDIAPVDYH VRRHDEIFAA INAVSESDAQ TRQQAAAIMR
160 170 180 190 200
QHLNEEGVIQ FLLKSFVDGE WRFNVPVLWD QYPHIVGWEK IPAWDHPALF
210 220 230 240 250
IPGGNSPYVS EQYRDDLLAQ FPQARAHVIA GAGHWVHAEK PDAVLRAIRR

YLND
Length:254
Mass (Da):28,437
Last modified:February 1, 1997 - v1
Checksum:i8B2F6E28713D9B8A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA Translation: AAC73780.1
AP009048 Genomic DNA Translation: BAA35335.1
PIRiE64803
RefSeqiNP_415212.1, NC_000913.3
WP_000773288.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC73780; AAC73780; b0686
BAA35335; BAA35335; BAA35335
GeneIDi945288
KEGGiecj:JW0673
eco:b0686
PATRICifig|1411691.4.peg.1590

Similar proteinsi

Entry informationi

Entry nameiYBFF_ECOLI
AccessioniPrimary (citable) accession number: P75736
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: March 28, 2018
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
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Main funding by: National Institutes of Health