Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative Rz endopeptidase from lambdoid prophage DLP12

Gene

rzpD

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Necessary for host cell lysis. It is believed to code for an endopeptidase that cleaves the amino-carboxyl cross-link between the diaminopimelic acid and D-alanine residues in the murein component of the bacterial cell wall (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Antimicrobial, Bacteriolytic enzyme, Hydrolase, Protease

Enzyme and pathway databases

BioCyciEcoCyc:G6311-MONOMER.
ECOL316407:JW5079-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative Rz endopeptidase from lambdoid prophage DLP12 (EC:3.4.-.-)
Gene namesi
Name:rzpD
Synonyms:ybcT
Ordered Locus Names:b0556, JW5079
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13636. rzpD.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 153153Putative Rz endopeptidase from lambdoid prophage DLP12PRO_0000077572Add
BLAST

Proteomic databases

PaxDbiP75719.

Interactioni

Protein-protein interaction databases

BioGridi4262925. 2 interactions.
STRINGi511145.b0556.

Structurei

3D structure databases

ProteinModelPortaliP75719.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4105SZK. Bacteria.
ENOG4111VX3. LUCA.
HOGENOMiHOG000119352.
InParanoidiP75719.
KOiK14744.
OMAiNQCISAN.
PhylomeDBiP75719.

Family and domain databases

InterProiIPR004929. Bacteriophage_Rz-type_lysis.
[Graphical view]
PfamiPF03245. Phage_lysis. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P75719-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRVTAIISA LIICIIVSLS WAVNHYRDNA IAYKVQRDKN ARELKLANAA
60 70 80 90 100
ITDMQMRQRD VAALDAKYTK ELADAKAEND ALRDDVAAGR RRLHIKAVCQ
110 120 130 140 150
SVREATTASG VDNAASPRLA DTAERDYFTL RERLITMQKQ LEGTQKYINE

QCR
Length:153
Mass (Da):17,226
Last modified:February 1, 1997 - v1
Checksum:iAAACE549D943B2FC
GO

Sequence cautioni

The sequence AAB40752 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U82598 Genomic DNA. Translation: AAB40752.1. Different initiation.
U00096 Genomic DNA. Translation: AAC73657.1.
AP009048 Genomic DNA. Translation: BAE76331.1.
PIRiB64788.
RefSeqiNP_415088.1. NC_000913.3.
WP_000092242.1. NZ_CP014270.1.

Genome annotation databases

EnsemblBacteriaiAAC73657; AAC73657; b0556.
BAE76331; BAE76331; BAE76331.
GeneIDi945929.
KEGGiecj:JW5079.
eco:b0556.
PATRICi32116278. VBIEscCol129921_0579.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U82598 Genomic DNA. Translation: AAB40752.1. Different initiation.
U00096 Genomic DNA. Translation: AAC73657.1.
AP009048 Genomic DNA. Translation: BAE76331.1.
PIRiB64788.
RefSeqiNP_415088.1. NC_000913.3.
WP_000092242.1. NZ_CP014270.1.

3D structure databases

ProteinModelPortaliP75719.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262925. 2 interactions.
STRINGi511145.b0556.

Proteomic databases

PaxDbiP75719.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73657; AAC73657; b0556.
BAE76331; BAE76331; BAE76331.
GeneIDi945929.
KEGGiecj:JW5079.
eco:b0556.
PATRICi32116278. VBIEscCol129921_0579.

Organism-specific databases

EchoBASEiEB3400.
EcoGeneiEG13636. rzpD.

Phylogenomic databases

eggNOGiENOG4105SZK. Bacteria.
ENOG4111VX3. LUCA.
HOGENOMiHOG000119352.
InParanoidiP75719.
KOiK14744.
OMAiNQCISAN.
PhylomeDBiP75719.

Enzyme and pathway databases

BioCyciEcoCyc:G6311-MONOMER.
ECOL316407:JW5079-MONOMER.

Miscellaneous databases

PROiP75719.

Family and domain databases

InterProiIPR004929. Bacteriophage_Rz-type_lysis.
[Graphical view]
PfamiPF03245. Phage_lysis. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRZPD_ECOLI
AccessioniPrimary (citable) accession number: P75719
Secondary accession number(s): P77084, Q2MBM5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: September 7, 2016
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

Encoded by the cryptic lambdoid prophage DLP12.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.