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Protein

Putative allantoin permease

Gene

ybbW

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Transport of allantoin.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Purine metabolism, Transport

Enzyme and pathway databases

BioCyciEcoCyc:B0511-MONOMER.
ECOL316407:JW0499-MONOMER.

Protein family/group databases

TCDBi2.A.39.3.8. the nucleobase:cation symporter-1 (ncs1) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative allantoin permease
Alternative name(s):
Allantoin transport protein
Gene namesi
Name:ybbW
Synonyms:glxB2
Ordered Locus Names:b0511, JW0499
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13618. ybbW.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 3434CytoplasmicSequence analysisAdd
BLAST
Transmembranei35 – 5521HelicalSequence analysisAdd
BLAST
Topological domaini56 – 583PeriplasmicSequence analysis
Transmembranei59 – 7921HelicalSequence analysisAdd
BLAST
Topological domaini80 – 11435CytoplasmicSequence analysisAdd
BLAST
Transmembranei115 – 13521HelicalSequence analysisAdd
BLAST
Topological domaini136 – 15520PeriplasmicSequence analysisAdd
BLAST
Transmembranei156 – 17621HelicalSequence analysisAdd
BLAST
Topological domaini177 – 19014CytoplasmicSequence analysisAdd
BLAST
Transmembranei191 – 21121HelicalSequence analysisAdd
BLAST
Topological domaini212 – 22413PeriplasmicSequence analysisAdd
BLAST
Transmembranei225 – 24521HelicalSequence analysisAdd
BLAST
Topological domaini246 – 26520CytoplasmicSequence analysisAdd
BLAST
Transmembranei266 – 28621HelicalSequence analysisAdd
BLAST
Topological domaini287 – 30620PeriplasmicSequence analysisAdd
BLAST
Transmembranei307 – 32721HelicalSequence analysisAdd
BLAST
Topological domaini328 – 34619CytoplasmicSequence analysisAdd
BLAST
Transmembranei347 – 36721HelicalSequence analysisAdd
BLAST
Topological domaini368 – 3725PeriplasmicSequence analysis
Transmembranei373 – 39321HelicalSequence analysisAdd
BLAST
Topological domaini394 – 42532CytoplasmicSequence analysisAdd
BLAST
Transmembranei426 – 44621HelicalSequence analysisAdd
BLAST
Topological domaini447 – 4471PeriplasmicSequence analysis
Transmembranei448 – 46821HelicalSequence analysisAdd
BLAST
Topological domaini469 – 48416CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 484484Putative allantoin permeasePRO_0000197930Add
BLAST

Proteomic databases

PaxDbiP75712.

Expressioni

Inductioni

By glyoxylate.

Interactioni

Protein-protein interaction databases

BioGridi4262820. 180 interactions.
STRINGi511145.b0511.

Structurei

3D structure databases

ProteinModelPortaliP75712.
SMRiP75712. Positions 19-418.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105EW8. Bacteria.
COG1953. LUCA.
HOGENOMiHOG000165632.
InParanoidiP75712.
KOiK10975.
OMAiNLAPRRI.
OrthoDBiEOG69WFGX.
PhylomeDBiP75712.

Family and domain databases

InterProiIPR012681. NCS1.
IPR001248. Pur-cyt_permease.
[Graphical view]
PfamiPF02133. Transp_cyt_pur. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00800. ncs1. 1 hit.

Sequencei

Sequence statusi: Complete.

P75712-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEHQRKLFQQ RGYSEDLLPK TQSQRTWKTF NYFTLWMGSV HNVPNYVMVG
60 70 80 90 100
GFFILGLSTF SIMLAIILSA FFIAAVMVLN GAAGSKYGVP FAMILRASYG
110 120 130 140 150
VRGALFPGLL RGGIAAIMWF GLQCYAGSLA CLILIGKIWP GFLTLGGDFT
160 170 180 190 200
LLGLSLPGLI TFLIFWLVNV GIGFGGGKVL NKFTAILNPC IYIVFGGMAI
210 220 230 240 250
WAISLVGIGP IFDYIPSGIQ KAENGGFLFL VVINAVVAVW AAPAVSASDF
260 270 280 290 300
TQNAHSFREQ ALGQTLGLVV AYILFAVAGV CIIAGASIHY GADTWNVLDI
310 320 330 340 350
VQRWDSLFAS FFAVLVILMT TISTNATGNI IPAGYQIAAI APTKLTYKNG
360 370 380 390 400
VLIASIISLL ICPWKLMENQ DSIYLFLDII GGMLGPVIGV MMAHYFVVMR
410 420 430 440 450
GQINLDELYT APGDYKYYDN GFNLTAFSVT LVAVILSLGG KFIHFMEPLS
460 470 480
RVSWFVGVIV AFAAYALLKK RTTAEKTGEQ KTIG
Length:484
Mass (Da):52,456
Last modified:November 1, 1997 - v2
Checksum:iAE3DA5FF5043BF62
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U89279 Genomic DNA. Translation: AAB93852.1.
U82664 Genomic DNA. Translation: AAB40263.1.
U00096 Genomic DNA. Translation: AAC73613.2.
AP009048 Genomic DNA. Translation: BAE76289.1.
PIRiF64782.
RefSeqiNP_415044.4. NC_000913.3.
WP_000401100.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73613; AAC73613; b0511.
BAE76289; BAE76289; BAE76289.
GeneIDi945138.
KEGGiecj:JW0499.
eco:b0511.
PATRICi32116179. VBIEscCol129921_0531.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U89279 Genomic DNA. Translation: AAB93852.1.
U82664 Genomic DNA. Translation: AAB40263.1.
U00096 Genomic DNA. Translation: AAC73613.2.
AP009048 Genomic DNA. Translation: BAE76289.1.
PIRiF64782.
RefSeqiNP_415044.4. NC_000913.3.
WP_000401100.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP75712.
SMRiP75712. Positions 19-418.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262820. 180 interactions.
STRINGi511145.b0511.

Protein family/group databases

TCDBi2.A.39.3.8. the nucleobase:cation symporter-1 (ncs1) family.

Proteomic databases

PaxDbiP75712.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73613; AAC73613; b0511.
BAE76289; BAE76289; BAE76289.
GeneIDi945138.
KEGGiecj:JW0499.
eco:b0511.
PATRICi32116179. VBIEscCol129921_0531.

Organism-specific databases

EchoBASEiEB3383.
EcoGeneiEG13618. ybbW.

Phylogenomic databases

eggNOGiENOG4105EW8. Bacteria.
COG1953. LUCA.
HOGENOMiHOG000165632.
InParanoidiP75712.
KOiK10975.
OMAiNLAPRRI.
OrthoDBiEOG69WFGX.
PhylomeDBiP75712.

Enzyme and pathway databases

BioCyciEcoCyc:B0511-MONOMER.
ECOL316407:JW0499-MONOMER.

Miscellaneous databases

PROiP75712.

Family and domain databases

InterProiIPR012681. NCS1.
IPR001248. Pur-cyt_permease.
[Graphical view]
PfamiPF02133. Transp_cyt_pur. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00800. ncs1. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli."
    Cusa E., Obradors N., Baldoma L., Badia J., Aguilar J.
    J. Bacteriol. 181:7479-7484(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12 / ECL1.
  2. "Sequence of minutes 4-25 of Escherichia coli."
    Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M., Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D., Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.
    Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  5. "Global topology analysis of the Escherichia coli inner membrane proteome."
    Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.
    Science 308:1321-1323(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
    Strain: K12 / MG1655 / ATCC 47076.

Entry informationi

Entry nameiALLP_ECOLI
AccessioniPrimary (citable) accession number: P75712
Secondary accession number(s): P77127, Q2MBR7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: January 20, 2016
This is version 114 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.