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Protein

Putative glycoside/cation symporter YagG

Gene

yagG

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processSymport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:B0270-MONOMER.

Protein family/group databases

TCDBi2.A.2.3.5. the glycoside-pentoside-hexuronide (gph):cation symporter family.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative glycoside/cation symporter YagG
Gene namesi
Name:yagG
Ordered Locus Names:b0270, JW0263
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13346. yagG.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 9CytoplasmicCurated9
Transmembranei10 – 30HelicalSequence analysisAdd BLAST21
Transmembranei31 – 51HelicalSequence analysisAdd BLAST21
Topological domaini52 – 78CytoplasmicCuratedAdd BLAST27
Transmembranei79 – 99HelicalSequence analysisAdd BLAST21
Topological domaini100 – 106PeriplasmicCurated7
Transmembranei107 – 127HelicalSequence analysisAdd BLAST21
Topological domaini128 – 150CytoplasmicCuratedAdd BLAST23
Transmembranei151 – 171HelicalSequence analysisAdd BLAST21
Topological domaini172 – 179PeriplasmicCurated8
Transmembranei180 – 200HelicalSequence analysisAdd BLAST21
Topological domaini201 – 262CytoplasmicCuratedAdd BLAST62
Transmembranei263 – 283HelicalSequence analysisAdd BLAST21
Topological domaini284 – 308PeriplasmicCuratedAdd BLAST25
Transmembranei309 – 329HelicalSequence analysisAdd BLAST21
Topological domaini330 – 366CytoplasmicCuratedAdd BLAST37
Transmembranei367 – 387HelicalSequence analysisAdd BLAST21
Topological domaini388 – 405PeriplasmicCuratedAdd BLAST18
Transmembranei406 – 426HelicalSequence analysisAdd BLAST21
Topological domaini427 – 460CytoplasmicCurated1 PublicationAdd BLAST34

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001707651 – 460Putative glycoside/cation symporter YagGAdd BLAST460

Proteomic databases

PaxDbiP75683.
PRIDEiP75683.

Interactioni

Protein-protein interaction databases

BioGridi4261987. 188 interactors.
DIPiDIP-11234N.
IntActiP75683. 2 interactors.
MINTiMINT-1263876.
STRINGi316385.ECDH10B_0257.

Structurei

3D structure databases

ProteinModelPortaliP75683.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105CT4. Bacteria.
COG2211. LUCA.
HOGENOMiHOG000222022.
InParanoidiP75683.
PhylomeDBiP75683.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiView protein in InterPro
IPR020846. MFS_dom.
IPR001927. Na/Gal_symport.
IPR018043. Na/Gal_symport_CS.
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00792. gph. 1 hit.
PROSITEiView protein in PROSITE
PS00872. NA_GALACTOSIDE_SYMP. 1 hit.

Sequencei

Sequence statusi: Complete.

P75683-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTQLTMKDKI GYGLGDTACG FVWQATMFLL AYFYTDVFGL SAGIMGTLFL
60 70 80 90 100
VSRVLDAVTD PLMGLLVDRT RTRHGQFRPF LLWGAIPFGI VCVLTFYTPD
110 120 130 140 150
FSAQGKIIYA CVTYILLTLV YTFVNVPYCA MPGVITADPK ERHALQSWRF
160 170 180 190 200
FLAAAGSLAI SGIALPLVSI IGKGDEQVGY FGAMCVLGLS GVVLLYVCFF
210 220 230 240 250
TTKERYTFEV QPGSSVAKDL KLLLGNSQWR IMCAFKMMAT CSNVVRGGAT
260 270 280 290 300
LYFVKYVMDH PELATQFLLY GSLATMFGSL CSSRLLGRFD RVTAFKWIIV
310 320 330 340 350
AYSLISLLIF VTPAEHIALI FALNILFLFV FNTTTPLQWL MASDVVDYEE
360 370 380 390 400
SRSGRRLDGL VFSTYLFSLK IGLAIGGAVV GWILAYVNYS ASSSVQPVEV
410 420 430 440 450
LTTIKILFCV VPVVLYAGMF IMLSLYKLTD ARVEAISRQL IKHRAAQGEA
460
VPDAATAASH
Length:460
Mass (Da):50,632
Last modified:February 1, 1997 - v1
Checksum:iAB600588E663C6B7
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti370K → N in AAB08691 (Ref. 1) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U70214 Genomic DNA. Translation: AAB08691.1.
U00096 Genomic DNA. Translation: AAC73373.1.
AP009048 Genomic DNA. Translation: BAE76054.1.
PIRiF64752.
RefSeqiNP_414804.1. NC_000913.3.
WP_000192863.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73373; AAC73373; b0270.
BAE76054; BAE76054; BAE76054.
GeneIDi944947.
KEGGiecj:JW0263.
eco:b0270.
PATRICifig|1411691.4.peg.2010.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiYAGG_ECOLI
AccessioniPrimary (citable) accession number: P75683
Secondary accession number(s): P71292, Q2MCF2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: July 5, 2017
This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families