Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative ferric transport system permease protein FbpB

Gene

fbpB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein uncertaini

Functioni

Part of the ABC transporter complex FbpABC (TC 3.A.1.10.1) involved in Fe3+ ions import. Probably responsible for the translocation of the substrate across the membrane (By similarity).By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Ion transport, Iron transport, Transport

Keywords - Ligandi

Iron

Enzyme and pathway databases

BioCyciEcoCyc:G6137-MONOMER.
ECOL316407:JW0255-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative ferric transport system permease protein FbpB
Gene namesi
Name:fbpB
Synonyms:afuB
Ordered Locus Names:b0263, JW0255
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14277. fbpB.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 3333CytoplasmicSequence analysisAdd
BLAST
Transmembranei34 – 5421HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini55 – 7622PeriplasmicSequence analysisAdd
BLAST
Transmembranei77 – 9721HelicalPROSITE-ProRule annotationAdd
BLAST
Topological domaini98 – 11518CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini‹1 – 115›115Putative ferric transport system permease protein FbpBPRO_0000060016Add
BLAST

Proteomic databases

EPDiP75681.
PRIDEiP75681.

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (FbpC), two transmembrane proteins (FbpB) and a solute-binding protein (FbpA).Curated

Protein-protein interaction databases

BioGridi4263057. 4 interactions.
STRINGi316407.85674407.

Structurei

3D structure databases

ProteinModelPortaliP75681.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 9797ABC transmembrane type-1PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 ABC transmembrane type-1 domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1178. LUCA.
HOGENOMiHOG000201003.
KOiK02011.
PhylomeDBiP75681.

Family and domain databases

CDDicd06261. TM_PBP2. 1 hit.
Gene3Di1.10.3720.10. 1 hit.
InterProiIPR000515. MetI-like.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

P75681-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GQIDKSLDEA SLSLRAGSLR TITHILLPLL RPAILSALIY SFVRAITTVS
60 70 80 90 100
AIVFLVTPDT RVATAYILNR VEDGEYGVAI AYGSILIVVM LAIIFIFDWL
110
IGESRTSRSK AKNQA
Length:115
Mass (Da):12,536
Last modified:December 1, 2000 - v2
Checksum:i4A7EBBB61C5B665B
GO

Sequence cautioni

The sequence BAA77931 differs from that shown. Reason: Erroneous initiation. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. No translation available.
AP009048 Genomic DNA. Translation: BAA77931.2. Different initiation.
PIRiG64751.

Genome annotation databases

EnsemblBacteriaiBAA77931; BAA77931; BAA77931.
KEGGiecj:JW0255.
PATRICi48659724. VBIEscCol107702_0258.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. No translation available.
AP009048 Genomic DNA. Translation: BAA77931.2. Different initiation.
PIRiG64751.

3D structure databases

ProteinModelPortaliP75681.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263057. 4 interactions.
STRINGi316407.85674407.

Proteomic databases

EPDiP75681.
PRIDEiP75681.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA77931; BAA77931; BAA77931.
KEGGiecj:JW0255.
PATRICi48659724. VBIEscCol107702_0258.

Organism-specific databases

EchoBASEiEB4025.
EcoGeneiEG14277. fbpB.

Phylogenomic databases

eggNOGiCOG1178. LUCA.
HOGENOMiHOG000201003.
KOiK02011.
PhylomeDBiP75681.

Enzyme and pathway databases

BioCyciEcoCyc:G6137-MONOMER.
ECOL316407:JW0255-MONOMER.

Family and domain databases

CDDicd06261. TM_PBP2. 1 hit.
Gene3Di1.10.3720.10. 1 hit.
InterProiIPR000515. MetI-like.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiFBPB_ECOLI
AccessioniPrimary (citable) accession number: P75681
Secondary accession number(s): Q9XB40
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: September 7, 2016
This is version 113 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Caution

Could be the product of a pseudogene. The original protein is truncated by an IS1 element which is inserted right before residue 1. What was the original N-terminal of this protein is not known. FbpA was presumably also deleted by this IS1 event.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.