Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative ferric transport system permease-like protein AfuB

Gene

afuB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein uncertaini

Functioni

A severely truncated paralog of the AfuB uptake protein, homologous only to the last 20% of the intact protein in Actinobacillus.Curated

Caution

Could be the product of a pseudogene. The original protein is truncated by an IS1 element which is inserted right before residue 6. What was the original N-terminal of this protein is not known. Other genes of the operon were presumably also deleted by this IS1 event.Curated

GO - Biological processi

Enzyme and pathway databases

BioCyciEcoCyc:G6137-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Putative ferric transport system permease-like protein AfuB
Gene namesi
Name:afuB
Synonyms:fbpB
Ordered Locus Names:b0263, JW0255
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG14277 afuB

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 38CytoplasmicSequence analysisAdd BLAST38
Transmembranei39 – 59HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini60 – 81PeriplasmicSequence analysisAdd BLAST22
Transmembranei82 – 102HelicalPROSITE-ProRule annotationAdd BLAST21
Topological domaini103 – 120CytoplasmicSequence analysis1 PublicationAdd BLAST18

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000600161 – 120Putative ferric transport system permease-like protein AfuBAdd BLAST120

Proteomic databases

EPDiP75681
PRIDEiP75681

Interactioni

Protein-protein interaction databases

BioGridi42630574 interactors.
STRINGi316385.ECDH10B_0249

Structurei

3D structure databases

ProteinModelPortaliP75681
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 102ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST102

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1178 LUCA
HOGENOMiHOG000201003
KOiK02011
PhylomeDBiP75681

Family and domain databases

CDDicd06261 TM_PBP2, 1 hit
Gene3Di1.10.3720.101 hit
InterProiView protein in InterPro
IPR000515 MetI-like
IPR035906 MetI-like_sf
PfamiView protein in Pfam
PF00528 BPD_transp_1, 1 hit
SUPFAMiSSF161098 SSF161098, 1 hit
PROSITEiView protein in PROSITE
PS50928 ABC_TM1, 1 hit

Sequencei

Sequence statusi: Complete.

P75681-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESLPGQIDK SLDEASLSLR AGSLRTITHI LLPLLRPAIL SALIYSFVRA
60 70 80 90 100
ITTVSAIVFL VTPDTRVATA YILNRVEDGE YGVAIAYGSI LIVVMLAIIF
110 120
IFDWLIGESR TSRSKAKNQA
Length:120
Mass (Da):13,093
Last modified:November 30, 2016 - v3
Checksum:iDF63F7D8DB7F8655
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA No translation available.
AP009048 Genomic DNA Translation: BAA77931.2
PIRiG64751

Genome annotation databases

EnsemblBacteriaiBAA77931; BAA77931; BAA77931
KEGGiecj:JW0255
PATRICifig|83333.103.peg.1017

Similar proteinsi

Entry informationi

Entry nameiAFUB_ECOLI
AccessioniPrimary (citable) accession number: P75681
Secondary accession number(s): Q9XB40
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 30, 2016
Last modified: March 28, 2018
This is version 127 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome