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P75587

- RIBF_MYCPN

UniProt

P75587 - RIBF_MYCPN

Protein

Putative riboflavin biosynthesis protein RibF

Gene

ribF

Organism
Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 83 (01 Oct 2014)
      Sequence version 1 (01 Feb 1997)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + riboflavin = ADP + FMN.
    ATP + FMN = diphosphate + FAD.

    Pathwayi

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. FMN adenylyltransferase activity Source: UniProtKB-EC
    3. riboflavin kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. FAD biosynthetic process Source: UniProtKB-UniPathway
    2. FMN biosynthetic process Source: UniProtKB-UniPathway
    3. riboflavin biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    Kinase, Nucleotidyltransferase, Transferase

    Keywords - Ligandi

    ATP-binding, FAD, Flavoprotein, FMN, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciMPNE272634:GJ6Z-165-MONOMER.
    UniPathwayiUPA00276; UER00406.
    UPA00277; UER00407.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative riboflavin biosynthesis protein RibF
    Including the following 2 domains:
    Riboflavin kinase (EC:2.7.1.26)
    Alternative name(s):
    Flavokinase
    FMN adenylyltransferase (EC:2.7.7.2)
    Alternative name(s):
    FAD pyrophosphorylase
    FAD synthase
    Gene namesi
    Name:ribF
    Ordered Locus Names:MPN_158
    ORF Names:MP673
    OrganismiMycoplasma pneumoniae (strain ATCC 29342 / M129)
    Taxonomic identifieri272634 [NCBI]
    Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
    ProteomesiUP000000808: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 269269Putative riboflavin biosynthesis protein RibFPRO_0000194146Add
    BLAST

    Proteomic databases

    PaxDbiP75587.

    Interactioni

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    itself1EBI-2260090,EBI-2260090

    Protein-protein interaction databases

    IntActiP75587. 1 interaction.
    STRINGi272634.MPN158.

    Structurei

    3D structure databases

    ProteinModelPortaliP75587.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the RibF family.Curated

    Phylogenomic databases

    eggNOGiCOG0196.
    KOiK11753.
    OMAiCESADLE.
    OrthoDBiEOG6QP0ZV.

    Family and domain databases

    Gene3Di2.40.30.30. 1 hit.
    3.40.50.620. 1 hit.
    InterProiIPR015864. FAD_synthase.
    IPR023468. Riboflavin_kinase.
    IPR002606. Riboflavin_kinase_bac.
    IPR015865. Riboflavin_kinase_bac/euk.
    IPR023465. Riboflavin_kinase_domain.
    IPR014729. Rossmann-like_a/b/a_fold.
    [Graphical view]
    PANTHERiPTHR22749. PTHR22749. 1 hit.
    PfamiPF06574. FAD_syn. 1 hit.
    PF01687. Flavokinase. 1 hit.
    [Graphical view]
    PIRSFiPIRSF004491. FAD_Synth. 1 hit.
    SMARTiSM00904. Flavokinase. 1 hit.
    [Graphical view]
    SUPFAMiSSF82114. SSF82114. 1 hit.
    TIGRFAMsiTIGR00083. ribF. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P75587-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQQTLIIGAF DGLHKGHQLL AQAASGPVVA LLIANIPSLQ SDWLYEPKQR    50
    QVQLQQHFQS VVHSYDVIEH NISAQAFFDQ IISPLRCQQL VVGADFCFGK 100
    DNQNADFLRR LFPNTTIIPK DSQTLSSSTI RQWLKQGQIE QANAVLLEPY 150
    FREGVVIRGN QQARFLGWPT ANITLKPYMV PLRCGSYVIT VTYHQTNYPG 200
    VGFISYKNDQ LVCETHLIGF SGDLYGKQLR FTFNQFIRPQ QKFSGVQALQ 250
    KAISGDLKQA QKWFAQSTN 269
    Length:269
    Mass (Da):30,435
    Last modified:February 1, 1997 - v1
    Checksum:i2E63D7BC7A8FA12D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00089 Genomic DNA. Translation: AAB96321.1.
    PIRiS73999.
    RefSeqiNP_109846.1. NC_000912.1.

    Genome annotation databases

    EnsemblBacteriaiAAB96321; AAB96321; MPN_158.
    GeneIDi877209.
    KEGGimpn:MPN158.
    PATRICi20021639. VBIMycPne110_0176.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00089 Genomic DNA. Translation: AAB96321.1 .
    PIRi S73999.
    RefSeqi NP_109846.1. NC_000912.1.

    3D structure databases

    ProteinModelPortali P75587.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi P75587. 1 interaction.
    STRINGi 272634.MPN158.

    Proteomic databases

    PaxDbi P75587.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAB96321 ; AAB96321 ; MPN_158 .
    GeneIDi 877209.
    KEGGi mpn:MPN158.
    PATRICi 20021639. VBIMycPne110_0176.

    Phylogenomic databases

    eggNOGi COG0196.
    KOi K11753.
    OMAi CESADLE.
    OrthoDBi EOG6QP0ZV.

    Enzyme and pathway databases

    UniPathwayi UPA00276 ; UER00406 .
    UPA00277 ; UER00407 .
    BioCyci MPNE272634:GJ6Z-165-MONOMER.

    Family and domain databases

    Gene3Di 2.40.30.30. 1 hit.
    3.40.50.620. 1 hit.
    InterProi IPR015864. FAD_synthase.
    IPR023468. Riboflavin_kinase.
    IPR002606. Riboflavin_kinase_bac.
    IPR015865. Riboflavin_kinase_bac/euk.
    IPR023465. Riboflavin_kinase_domain.
    IPR014729. Rossmann-like_a/b/a_fold.
    [Graphical view ]
    PANTHERi PTHR22749. PTHR22749. 1 hit.
    Pfami PF06574. FAD_syn. 1 hit.
    PF01687. Flavokinase. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF004491. FAD_Synth. 1 hit.
    SMARTi SM00904. Flavokinase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF82114. SSF82114. 1 hit.
    TIGRFAMsi TIGR00083. ribF. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
      Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
      Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 29342 / M129.

    Entry informationi

    Entry nameiRIBF_MYCPN
    AccessioniPrimary (citable) accession number: P75587
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: February 1, 1997
    Last modified: October 1, 2014
    This is version 83 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Multifunctional enzyme, Reference proteome

    Documents

    1. Mycoplasma pneumoniae
      Mycoplasma pneumoniae (strain M129): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3