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P75561

- Y108_MYCPN

UniProt

P75561 - Y108_MYCPN

Protein

Uncharacterized adenine-specific methylase MPN_108

Gene

MPN_108

Organism
Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 80 (01 Oct 2014)
      Sequence version 1 (01 Feb 1997)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine + DNA 6-methylaminopurine.

    GO - Molecular functioni

    1. DNA binding Source: InterPro
    2. site-specific DNA-methyltransferase (adenine-specific) activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Methyltransferase, Transferase

    Keywords - Ligandi

    S-adenosyl-L-methionine

    Enzyme and pathway databases

    BioCyciMPNE272634:GJ6Z-114-MONOMER.

    Protein family/group databases

    REBASEi27678. MpnORF108P.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uncharacterized adenine-specific methylase MPN_108 (EC:2.1.1.72)
    Gene namesi
    Ordered Locus Names:MPN_108
    ORF Names:C09_orf404, MP046
    OrganismiMycoplasma pneumoniae (strain ATCC 29342 / M129)
    Taxonomic identifieri272634 [NCBI]
    Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
    ProteomesiUP000000808: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 404404Uncharacterized adenine-specific methylase MPN_108PRO_0000088016Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    IntActiP75561. 1 interaction.
    STRINGi272634.MPN108.

    Structurei

    3D structure databases

    ProteinModelPortaliP75561.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the N(4)/N(6)-methyltransferase family.Curated

    Phylogenomic databases

    eggNOGiCOG0827.
    KOiK00571.
    OMAiMEYMIAR.
    OrthoDBiEOG6HQSKB.

    Family and domain databases

    Gene3Di3.40.50.150. 3 hits.
    InterProiIPR002052. DNA_methylase_N6_adenine_CS.
    IPR011639. RM_methylase_Eco57I.
    IPR029063. SAM-dependent_MTases-like.
    [Graphical view]
    PfamiPF07669. Eco57I. 1 hit.
    [Graphical view]
    SUPFAMiSSF53335. SSF53335. 2 hits.
    PROSITEiPS00092. N6_MTASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P75561-1 [UniParc]FASTAAdd to Basket

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    MSQNGDKDHE LIQGKVKSKT EIEDSVILDQ DTLQGKGEEK TKLDELIRWE    50
    AEKNDLLKLI DNVGNDEVFT TVETCQRMLD DLFPQDHEVW SNPDLKWLNP 100
    CDKNGVFFRE IALRLDKGLA KVIPDEYERK KHIMTKMLFS IDLTKFTSLM 150
    VRRTLYYCIK ANKRKTSEDE GCAIANGAWF NNECGNVVKP YKEHYFDKQG 200
    KNKKCKFCRT DEKFKYQQSS SNEKYAYDFI HLNPNEYESY FKTNFGVMKF 250
    DVIIGNPPYQ LANNRGGDAG DGNGANPIFQ EFILRALELQ PKYLAMIVPA 300
    RWINSSEKVF LKFRAKLQKS NGFKGINIFF DSKHCFPNRQ IKGGVCYFNW 350
    QNGYEGQTLI TTKSSKKGKQ EEIETYKRDF FAPVLNNTEQ VIFRKKFDTT 400
    FIKR 404
    Length:404
    Mass (Da):47,115
    Last modified:February 1, 1997 - v1
    Checksum:iD096EEF4E1CD6895
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00089 Genomic DNA. Translation: AAB95694.1.
    PIRiS73372.
    RefSeqiNP_109796.1. NC_000912.1.
    WP_010874465.1. NC_000912.1.

    Genome annotation databases

    EnsemblBacteriaiAAB95694; AAB95694; MPN_108.
    GeneIDi877203.
    KEGGimpn:MPN108.
    PATRICi20021513. VBIMycPne110_0114.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00089 Genomic DNA. Translation: AAB95694.1 .
    PIRi S73372.
    RefSeqi NP_109796.1. NC_000912.1.
    WP_010874465.1. NC_000912.1.

    3D structure databases

    ProteinModelPortali P75561.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi P75561. 1 interaction.
    STRINGi 272634.MPN108.

    Protein family/group databases

    REBASEi 27678. MpnORF108P.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAB95694 ; AAB95694 ; MPN_108 .
    GeneIDi 877203.
    KEGGi mpn:MPN108.
    PATRICi 20021513. VBIMycPne110_0114.

    Phylogenomic databases

    eggNOGi COG0827.
    KOi K00571.
    OMAi MEYMIAR.
    OrthoDBi EOG6HQSKB.

    Enzyme and pathway databases

    BioCyci MPNE272634:GJ6Z-114-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.150. 3 hits.
    InterProi IPR002052. DNA_methylase_N6_adenine_CS.
    IPR011639. RM_methylase_Eco57I.
    IPR029063. SAM-dependent_MTases-like.
    [Graphical view ]
    Pfami PF07669. Eco57I. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53335. SSF53335. 2 hits.
    PROSITEi PS00092. N6_MTASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
      Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
      Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 29342 / M129.

    Entry informationi

    Entry nameiY108_MYCPN
    AccessioniPrimary (citable) accession number: P75561
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 10, 2002
    Last sequence update: February 1, 1997
    Last modified: October 1, 2014
    This is version 80 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Mycoplasma pneumoniae
      Mycoplasma pneumoniae (strain M129): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3