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P75561 (Y108_MYCPN) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uncharacterized adenine-specific methylase MPN_108

EC=2.1.1.72
Gene names
Ordered Locus Names:MPN_108
ORF Names:C09_orf404, MP046
OrganismMycoplasma pneumoniae (strain ATCC 29342 / M129) [Reference proteome] [HAMAP]
Taxonomic identifier272634 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length404 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine + DNA 6-methylaminopurine.

Sequence similarities

Belongs to the N(4)/N(6)-methyltransferase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 404404Uncharacterized adenine-specific methylase MPN_108
PRO_0000088016

Sequences

Sequence LengthMass (Da)Tools
P75561 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: D096EEF4E1CD6895

FASTA40447,115
        10         20         30         40         50         60 
MSQNGDKDHE LIQGKVKSKT EIEDSVILDQ DTLQGKGEEK TKLDELIRWE AEKNDLLKLI 

        70         80         90        100        110        120 
DNVGNDEVFT TVETCQRMLD DLFPQDHEVW SNPDLKWLNP CDKNGVFFRE IALRLDKGLA 

       130        140        150        160        170        180 
KVIPDEYERK KHIMTKMLFS IDLTKFTSLM VRRTLYYCIK ANKRKTSEDE GCAIANGAWF 

       190        200        210        220        230        240 
NNECGNVVKP YKEHYFDKQG KNKKCKFCRT DEKFKYQQSS SNEKYAYDFI HLNPNEYESY 

       250        260        270        280        290        300 
FKTNFGVMKF DVIIGNPPYQ LANNRGGDAG DGNGANPIFQ EFILRALELQ PKYLAMIVPA 

       310        320        330        340        350        360 
RWINSSEKVF LKFRAKLQKS NGFKGINIFF DSKHCFPNRQ IKGGVCYFNW QNGYEGQTLI 

       370        380        390        400 
TTKSSKKGKQ EEIETYKRDF FAPVLNNTEQ VIFRKKFDTT FIKR 

« Hide

References

[1]"Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29342 / M129.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U00089 Genomic DNA. Translation: AAB95694.1.
PIRS73372.
RefSeqNP_109796.1. NC_000912.1.

3D structure databases

ProteinModelPortalP75561.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActP75561. 1 interaction.
STRING272634.MPN108.

Protein family/group databases

REBASE27678. MpnORF108P.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB95694; AAB95694; MPN_108.
GeneID877203.
KEGGmpn:MPN108.
PATRIC20021513. VBIMycPne110_0114.

Phylogenomic databases

eggNOGCOG0827.
KOK00571.
OMAMEYMIAR.
OrthoDBEOG6HQSKB.

Enzyme and pathway databases

BioCycMPNE272634:GJ6Z-114-MONOMER.

Family and domain databases

Gene3D3.40.50.150. 3 hits.
InterProIPR002052. DNA_methylase_N6_adenine_CS.
IPR011639. RM_methylase_Eco57I.
IPR029063. SAM-dependent_MTases-like.
[Graphical view]
PfamPF07669. Eco57I. 1 hit.
[Graphical view]
SUPFAMSSF53335. SSF53335. 2 hits.
PROSITEPS00092. N6_MTASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameY108_MYCPN
AccessionPrimary (citable) accession number: P75561
Entry history
Integrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: February 1, 1997
Last modified: June 11, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Mycoplasma pneumoniae

Mycoplasma pneumoniae (strain M129): entries and gene names