Reviewed, UniProtKB/Swiss-Prot P75561 (Y108_MYCPN)

Names and origin

Protein names

Recommended name:
    Uncharacterized adenine-specific methylase MPN_108
    EC=2.1.1.72

Gene names

Ordered Locus Names:	MPN_108
ORF Names:	C09_orf404, MP046

Organism

Mycoplasma pneumoniae [Complete proteome] [HAMAP]

Taxonomic identifier

2104 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma

Protein attributes

Sequence length	404 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine + DNA 6-methylaminopurine.
Sequence similarities	Belongs to the N(4)/N(6)-methyltransferase family.

Ontologies

Keywords
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA modification Inferred from electronic annotation. Source: InterPro methylation Inferred from electronic annotation. Source: InterPro
Molecular function	DNA binding Inferred from electronic annotation. Source: InterPro site-specific DNA-methyltransferase (adenine-specific) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 404	404	Uncharacterized adenine-specific methylase MPN_108		PRO_0000088016

Sequences

	Sequence		Length	Mass (Da)
	P75561-1 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: D096EEF4E1CD6895	FASTA	404	47,115
	10 20 30 40 50 60 MSQNGDKDHE LIQGKVKSKT EIEDSVILDQ DTLQGKGEEK TKLDELIRWE AEKNDLLKLI 70 80 90 100 110 120 DNVGNDEVFT TVETCQRMLD DLFPQDHEVW SNPDLKWLNP CDKNGVFFRE IALRLDKGLA 130 140 150 160 170 180 KVIPDEYERK KHIMTKMLFS IDLTKFTSLM VRRTLYYCIK ANKRKTSEDE GCAIANGAWF 190 200 210 220 230 240 NNECGNVVKP YKEHYFDKQG KNKKCKFCRT DEKFKYQQSS SNEKYAYDFI HLNPNEYESY 250 260 270 280 290 300 FKTNFGVMKF DVIIGNPPYQ LANNRGGDAG DGNGANPIFQ EFILRALELQ PKYLAMIVPA 310 320 330 340 350 360 RWINSSEKVF LKFRAKLQKS NGFKGINIFF DSKHCFPNRQ IKGGVCYFNW QNGYEGQTLI 370 380 390 400 TTKSSKKGKQ EEIETYKRDF FAPVLNNTEQ VIFRKKFDTT FIKR

References

[1]

"Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae." Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R. Nucleic Acids Res. 24:4420-4449(1996) [PubMed: 8948633] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29342 / M129.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U00089 Genomic DNA. Translation: AAB95694.1.
PIR	S73372.
RefSeq	NP_109796.1.
3D structure databases
SMR	P75561. Positions 249-348.
ModBase	Search...
Genome annotation databases
GeneID	877203.
GenomeReviews	Gene locus MPN_108 in contig U00089_GR.
KEGG	mpn:MPN108.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG129982.
Enzyme and pathway databases
BioCyc	MPNE272634:MPN108-MONOMER.
BRENDA	2.1.1.72. 39500.
Family and domain databases
InterPro	IPR002052. DNA_methylase_N6_adenine_CS. [Graphical view]
PROSITE	PS00092. N6_MTASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y108_MYCPN

Accession

Primary (citable) accession number: P75561

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 10, 2002
Last sequence update:	February 1, 1997
Last modified:	February 9, 2010
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)