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Protein

Uncharacterized adenine-specific methylase MPN_108

Gene

MPN_108

Organism
Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine + DNA 6-methylaminopurine.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciMPNE272634:GJ6Z-114-MONOMER.

Protein family/group databases

REBASEi27678. MpnORF108P.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized adenine-specific methylase MPN_108 (EC:2.1.1.72)
Gene namesi
Ordered Locus Names:MPN_108
ORF Names:C09_orf404, MP046
OrganismiMycoplasma pneumoniae (strain ATCC 29342 / M129)
Taxonomic identifieri272634 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000808 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 404404Uncharacterized adenine-specific methylase MPN_108PRO_0000088016Add
BLAST

Interactioni

Protein-protein interaction databases

IntActiP75561. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliP75561.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the N(4)/N(6)-methyltransferase family.Curated

Phylogenomic databases

eggNOGiCOG0827.
KOiK00571.
OrthoDBiEOG6HQSKB.

Family and domain databases

Gene3Di3.40.50.150. 3 hits.
InterProiIPR002052. DNA_methylase_N6_adenine_CS.
IPR011639. RM_methylase_Eco57I.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PfamiPF07669. Eco57I. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 2 hits.
PROSITEiPS00092. N6_MTASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P75561-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQNGDKDHE LIQGKVKSKT EIEDSVILDQ DTLQGKGEEK TKLDELIRWE
60 70 80 90 100
AEKNDLLKLI DNVGNDEVFT TVETCQRMLD DLFPQDHEVW SNPDLKWLNP
110 120 130 140 150
CDKNGVFFRE IALRLDKGLA KVIPDEYERK KHIMTKMLFS IDLTKFTSLM
160 170 180 190 200
VRRTLYYCIK ANKRKTSEDE GCAIANGAWF NNECGNVVKP YKEHYFDKQG
210 220 230 240 250
KNKKCKFCRT DEKFKYQQSS SNEKYAYDFI HLNPNEYESY FKTNFGVMKF
260 270 280 290 300
DVIIGNPPYQ LANNRGGDAG DGNGANPIFQ EFILRALELQ PKYLAMIVPA
310 320 330 340 350
RWINSSEKVF LKFRAKLQKS NGFKGINIFF DSKHCFPNRQ IKGGVCYFNW
360 370 380 390 400
QNGYEGQTLI TTKSSKKGKQ EEIETYKRDF FAPVLNNTEQ VIFRKKFDTT

FIKR
Length:404
Mass (Da):47,115
Last modified:February 1, 1997 - v1
Checksum:iD096EEF4E1CD6895
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00089 Genomic DNA. Translation: AAB95694.1.
PIRiS73372.
RefSeqiNP_109796.1. NC_000912.1.
WP_010874465.1. NC_000912.1.

Genome annotation databases

EnsemblBacteriaiAAB95694; AAB95694; MPN_108.
GeneIDi877203.
KEGGimpn:MPN108.
PATRICi20021513. VBIMycPne110_0114.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00089 Genomic DNA. Translation: AAB95694.1.
PIRiS73372.
RefSeqiNP_109796.1. NC_000912.1.
WP_010874465.1. NC_000912.1.

3D structure databases

ProteinModelPortaliP75561.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP75561. 1 interaction.

Protein family/group databases

REBASEi27678. MpnORF108P.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB95694; AAB95694; MPN_108.
GeneIDi877203.
KEGGimpn:MPN108.
PATRICi20021513. VBIMycPne110_0114.

Phylogenomic databases

eggNOGiCOG0827.
KOiK00571.
OrthoDBiEOG6HQSKB.

Enzyme and pathway databases

BioCyciMPNE272634:GJ6Z-114-MONOMER.

Family and domain databases

Gene3Di3.40.50.150. 3 hits.
InterProiIPR002052. DNA_methylase_N6_adenine_CS.
IPR011639. RM_methylase_Eco57I.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PfamiPF07669. Eco57I. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 2 hits.
PROSITEiPS00092. N6_MTASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
    Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
    Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29342 / M129.

Entry informationi

Entry nameiY108_MYCPN
AccessioniPrimary (citable) accession number: P75561
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: February 1, 1997
Last modified: June 24, 2015
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Mycoplasma pneumoniae
    Mycoplasma pneumoniae (strain M129): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.