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P75534

- GATA_MYCPN

UniProt

P75534 - GATA_MYCPN

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Protein
Glutamyl-tRNA(Gln) amidotransferase subunit A
Gene
gatA, MPN_237, MP594
Organism
Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) By similarity.UniRule annotation

Catalytic activityi

ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei68 – 681Charge relay system By similarity
Active sitei143 – 1431Charge relay system By similarity
Active sitei167 – 1671Acyl-ester intermediate By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. translation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMPNE272634:GJ6Z-244-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamyl-tRNA(Gln) amidotransferase subunit A (EC:6.3.5.7)
Short name:
Glu-ADT subunit A
Gene namesi
Name:gatA
Ordered Locus Names:MPN_237
ORF Names:MP594
OrganismiMycoplasma pneumoniae (strain ATCC 29342 / M129)
Taxonomic identifieri272634 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000808: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 478478Glutamyl-tRNA(Gln) amidotransferase subunit AUniRule annotation
PRO_0000105179Add
BLAST

Proteomic databases

PaxDbiP75534.

Interactioni

Subunit structurei

Heterotrimer of A, B and C subunits By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi272634.MPN237.

Structurei

3D structure databases

ProteinModelPortaliP75534.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0154.
KOiK02433.
OMAiYDILLAY.
OrthoDBiEOG61P6R9.

Family and domain databases

Gene3Di3.90.1300.10. 1 hit.
HAMAPiMF_00120. GatA.
InterProiIPR000120. Amidase.
IPR020556. Amidase_CS.
IPR023631. Amidase_dom.
IPR004412. GatA.
[Graphical view]
PANTHERiPTHR11895. PTHR11895. 1 hit.
PfamiPF01425. Amidase. 1 hit.
[Graphical view]
SUPFAMiSSF75304. SSF75304. 1 hit.
TIGRFAMsiTIGR00132. gatA. 1 hit.
PROSITEiPS00571. AMIDASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P75534-1 [UniParc]FASTAAdd to Basket

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MKSQILKLQQ TLTKKPASIN PLLQQIDGAI NEHWSSNFLL KNTVEWAQAQ    50
APKNRSKSPL NNIPFVLKDN IATKGIVTTG GSRFLEDYIP PFSATVFELL 100
NNSGALLVGK ANLDEFGLGG TGLHSGFGFV HHPWNETLIP GGSSSGSAYA 150
VARGIVPFSI GTDTGDSVRR PASICNIVGF KPTYGLISRN GVYPYAPSLD 200
HVGIFARYVY DVALVSDEII KHDKADFSAQ KSPDAGKFTR SLKESFNKQI 250
KIGYLKPLEE WFDIELSKKW NSLKERITLE GCELIPFHFP LELLEVIDPV 300
YKLISYSEAV SCYSNLTGIV FGQKLFEPNQ ASDFSKTITA NRDRFFGEQL 350
KRRFIIGAFG TDKNNFTKYF EKAQKIRRVM VDAYLNLFKE ADFIVSPSAS 400
GFTKTIAAVQ KGESFTNLVD DFLQLANFAG NPSITIPWLV KQKDQTIGLS 450
VNANCFHDKQ LLQVAAWLEE LFQIEHDD 478
Length:478
Mass (Da):53,230
Last modified:February 1, 1997 - v1
Checksum:iF228E9AE4F641071
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00089 Genomic DNA. Translation: AAB96242.1.
PIRiS73920.
RefSeqiNP_109925.1. NC_000912.1.

Genome annotation databases

EnsemblBacteriaiAAB96242; AAB96242; MPN_237.
GeneIDi877201.
KEGGimpn:MPN237.
PATRICi20021799. VBIMycPne110_0256.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00089 Genomic DNA. Translation: AAB96242.1 .
PIRi S73920.
RefSeqi NP_109925.1. NC_000912.1.

3D structure databases

ProteinModelPortali P75534.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272634.MPN237.

Proteomic databases

PaxDbi P75534.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAB96242 ; AAB96242 ; MPN_237 .
GeneIDi 877201.
KEGGi mpn:MPN237.
PATRICi 20021799. VBIMycPne110_0256.

Phylogenomic databases

eggNOGi COG0154.
KOi K02433.
OMAi YDILLAY.
OrthoDBi EOG61P6R9.

Enzyme and pathway databases

BioCyci MPNE272634:GJ6Z-244-MONOMER.

Family and domain databases

Gene3Di 3.90.1300.10. 1 hit.
HAMAPi MF_00120. GatA.
InterProi IPR000120. Amidase.
IPR020556. Amidase_CS.
IPR023631. Amidase_dom.
IPR004412. GatA.
[Graphical view ]
PANTHERi PTHR11895. PTHR11895. 1 hit.
Pfami PF01425. Amidase. 1 hit.
[Graphical view ]
SUPFAMi SSF75304. SSF75304. 1 hit.
TIGRFAMsi TIGR00132. gatA. 1 hit.
PROSITEi PS00571. AMIDASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
    Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
    Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29342 / M129.

Entry informationi

Entry nameiGATA_MYCPN
AccessioniPrimary (citable) accession number: P75534
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: May 14, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Mycoplasma pneumoniae
    Mycoplasma pneumoniae (strain M129): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi