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P75524

- PKNS_MYCPN

UniProt

P75524 - PKNS_MYCPN

Protein

Putative serine/threonine-protein kinase

Gene

MPN_248

Organism
Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 88 (01 Oct 2014)
      Sequence version 1 (01 Feb 1997)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei164 – 1641Proton acceptorPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. protein serine/threonine kinase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciMPNE272634:GJ6Z-255-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative serine/threonine-protein kinase (EC:2.7.11.1)
    Gene namesi
    Ordered Locus Names:MPN_248
    ORF Names:MP584
    OrganismiMycoplasma pneumoniae (strain ATCC 29342 / M129)
    Taxonomic identifieri272634 [NCBI]
    Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
    ProteomesiUP000000808: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 389389Putative serine/threonine-protein kinasePRO_0000171202Add
    BLAST

    Proteomic databases

    PaxDbiP75524.

    Interactioni

    Protein-protein interaction databases

    IntActiP75524. 1 interaction.
    STRINGi272634.MPN248.

    Structurei

    3D structure databases

    ProteinModelPortaliP75524.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini15 – 356342Protein kinasePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
    Contains 1 protein kinase domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0515.
    KOiK08884.
    OMAiTDENSLF.
    OrthoDBiEOG62NX1C.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF00069. Pkinase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P75524-1 [UniParc]FASTAAdd to Basket

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    MALNLKIGDI VQNKYRIEKL INRGGMNSYL FLASNLHVQE FGPLQKRQFT    50
    RLVLKVVQRT DKINDNNWKK FLDGTITTTR VSHKNLVQTF DVVSPRLSVL 100
    SENQVIVLED TVMIVMEYVD GPSLREMLNQ KGYFSVQEVV YYFTKLVKVI 150
    NYLHSFEHQI IHRDLKPENI LFTSNLTDIK LLDFGIASAV IRNAEKTEVL 200
    TDENSLFGTV SYMTPEVLES TVNKEGKRIR KPPTVQYDIY SLGVILFEML 250
    VGRVPFNKSI DPKKERETIQ KARNFDVPLM GNLRSDVPVS LENIVFKCTA 300
    VKRENSKWMY SDTKQLLADL AQWQTEQTLI KPVHERILEG QNEMRELMVS 350
    NYLPWYLRKG VLIFFSVVLL ALLIAVVSFF IITGVVVHS 389
    Length:389
    Mass (Da):44,882
    Last modified:February 1, 1997 - v1
    Checksum:i838E5CDB5AD49B15
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00089 Genomic DNA. Translation: AAB96232.1.
    PIRiS73910.
    RefSeqiNP_109936.1. NC_000912.1.

    Genome annotation databases

    EnsemblBacteriaiAAB96232; AAB96232; MPN_248.
    GeneIDi876966.
    KEGGimpn:MPN248.
    PATRICi20021821. VBIMycPne110_0267.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00089 Genomic DNA. Translation: AAB96232.1 .
    PIRi S73910.
    RefSeqi NP_109936.1. NC_000912.1.

    3D structure databases

    ProteinModelPortali P75524.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi P75524. 1 interaction.
    STRINGi 272634.MPN248.

    Proteomic databases

    PaxDbi P75524.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAB96232 ; AAB96232 ; MPN_248 .
    GeneIDi 876966.
    KEGGi mpn:MPN248.
    PATRICi 20021821. VBIMycPne110_0267.

    Phylogenomic databases

    eggNOGi COG0515.
    KOi K08884.
    OMAi TDENSLF.
    OrthoDBi EOG62NX1C.

    Enzyme and pathway databases

    BioCyci MPNE272634:GJ6Z-255-MONOMER.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
      Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
      Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 29342 / M129.

    Entry informationi

    Entry nameiPKNS_MYCPN
    AccessioniPrimary (citable) accession number: P75524
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: February 1, 1997
    Last modified: October 1, 2014
    This is version 88 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Mycoplasma pneumoniae
      Mycoplasma pneumoniae (strain M129): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3