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Protein

Putative serine/threonine-protein kinase

Gene

MPN_248

Organism
Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei164 – 1641Proton acceptorPROSITE-ProRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMPNE272634:GJ6Z-255-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative serine/threonine-protein kinase (EC:2.7.11.1)
Gene namesi
Ordered Locus Names:MPN_248
ORF Names:MP584
OrganismiMycoplasma pneumoniae (strain ATCC 29342 / M129)
Taxonomic identifieri272634 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000808: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 389389Putative serine/threonine-protein kinasePRO_0000171202Add
BLAST

Proteomic databases

PaxDbiP75524.

Interactioni

Protein-protein interaction databases

IntActiP75524. 1 interaction.
STRINGi272634.MPN248.

Structurei

3D structure databases

ProteinModelPortaliP75524.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini15 – 356342Protein kinasePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG0515.
KOiK08884.
OMAiTDENSLF.
OrthoDBiEOG62NX1C.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P75524-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MALNLKIGDI VQNKYRIEKL INRGGMNSYL FLASNLHVQE FGPLQKRQFT
60 70 80 90 100
RLVLKVVQRT DKINDNNWKK FLDGTITTTR VSHKNLVQTF DVVSPRLSVL
110 120 130 140 150
SENQVIVLED TVMIVMEYVD GPSLREMLNQ KGYFSVQEVV YYFTKLVKVI
160 170 180 190 200
NYLHSFEHQI IHRDLKPENI LFTSNLTDIK LLDFGIASAV IRNAEKTEVL
210 220 230 240 250
TDENSLFGTV SYMTPEVLES TVNKEGKRIR KPPTVQYDIY SLGVILFEML
260 270 280 290 300
VGRVPFNKSI DPKKERETIQ KARNFDVPLM GNLRSDVPVS LENIVFKCTA
310 320 330 340 350
VKRENSKWMY SDTKQLLADL AQWQTEQTLI KPVHERILEG QNEMRELMVS
360 370 380
NYLPWYLRKG VLIFFSVVLL ALLIAVVSFF IITGVVVHS
Length:389
Mass (Da):44,882
Last modified:February 1, 1997 - v1
Checksum:i838E5CDB5AD49B15
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00089 Genomic DNA. Translation: AAB96232.1.
PIRiS73910.
RefSeqiNP_109936.1. NC_000912.1.
WP_010874605.1. NC_000912.1.

Genome annotation databases

EnsemblBacteriaiAAB96232; AAB96232; MPN_248.
GeneIDi876966.
KEGGimpn:MPN248.
PATRICi20021821. VBIMycPne110_0267.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00089 Genomic DNA. Translation: AAB96232.1.
PIRiS73910.
RefSeqiNP_109936.1. NC_000912.1.
WP_010874605.1. NC_000912.1.

3D structure databases

ProteinModelPortaliP75524.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP75524. 1 interaction.
STRINGi272634.MPN248.

Proteomic databases

PaxDbiP75524.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB96232; AAB96232; MPN_248.
GeneIDi876966.
KEGGimpn:MPN248.
PATRICi20021821. VBIMycPne110_0267.

Phylogenomic databases

eggNOGiCOG0515.
KOiK08884.
OMAiTDENSLF.
OrthoDBiEOG62NX1C.

Enzyme and pathway databases

BioCyciMPNE272634:GJ6Z-255-MONOMER.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
    Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
    Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29342 / M129.

Entry informationi

Entry nameiPKNS_MYCPN
AccessioniPrimary (citable) accession number: P75524
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: January 7, 2015
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Mycoplasma pneumoniae
    Mycoplasma pneumoniae (strain M129): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.