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P75524 (PKNS_MYCPN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Putative serine/threonine-protein kinase
EC=2.7.11.1
Gene names
Ordered Locus Names:MPN_248
ORF Names:MP584
OrganismMycoplasma pneumoniae (strain ATCC 29342 / M129) [Reference proteome] [HAMAP]
Taxonomic identifier272634 [NCBI]
Taxonomic lineageBacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma ›

Protein attributes

Sequence length389 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 1 protein kinase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 389389Putative serine/threonine-protein kinase
PRO_0000171202

Regions

Domain15 – 356342Protein kinase

Sites

Active site1641Proton acceptor By similarity

Sequences

Sequence LengthMass (Da)Tools
P75524 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 838E5CDB5AD49B15

FASTA38944,882
        10         20         30         40         50         60 
MALNLKIGDI VQNKYRIEKL INRGGMNSYL FLASNLHVQE FGPLQKRQFT RLVLKVVQRT 

        70         80         90        100        110        120 
DKINDNNWKK FLDGTITTTR VSHKNLVQTF DVVSPRLSVL SENQVIVLED TVMIVMEYVD 

       130        140        150        160        170        180 
GPSLREMLNQ KGYFSVQEVV YYFTKLVKVI NYLHSFEHQI IHRDLKPENI LFTSNLTDIK 

       190        200        210        220        230        240 
LLDFGIASAV IRNAEKTEVL TDENSLFGTV SYMTPEVLES TVNKEGKRIR KPPTVQYDIY 

       250        260        270        280        290        300 
SLGVILFEML VGRVPFNKSI DPKKERETIQ KARNFDVPLM GNLRSDVPVS LENIVFKCTA 

       310        320        330        340        350        360 
VKRENSKWMY SDTKQLLADL AQWQTEQTLI KPVHERILEG QNEMRELMVS NYLPWYLRKG 

       370        380 
VLIFFSVVLL ALLIAVVSFF IITGVVVHS

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References

[1]"Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29342 / M129.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		U00089 Genomic DNA. Translation: AAB96232.1.
PIRS73910.
RefSeqNP_109936.1. NC_000912.1.

3D structure databases

ProteinModelPortalP75524.
ModBaseSearch...

Protein-protein interaction databases

IntActP75524. 1 interaction.
STRING272634.MPN248.

Proteomic databases

PaxDbP75524.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB96232; AAB96232; MPN_248.
GeneID876966.
KEGGmpn:MPN248.
PATRIC20021821. VBIMycPne110_0267.

Phylogenomic databases

eggNOGCOG0515.
KOK08884.
OMARPREINP.
ProtClustDBCLSK437086.

Enzyme and pathway databases

BioCycMPNE272634:GJ6Z-255-MONOMER.

Family and domain databases

InterProIPR020636. Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_cat_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PANTHERPTHR24347. PTHR24347. 1 hit.
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMSSF56112. Kinase_like. 1 hit.
PROSITEPS00107. PROTEIN_KINASE_ATP. False negative.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePKNS_MYCPN
AccessionPrimary (citable) accession number: P75524
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: May 1, 2013
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Mycoplasma pneumoniae

Mycoplasma pneumoniae (strain M129): entries and gene names

SIMILARITY comments

Index of protein domains and families

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