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P75499 (GLF_MYCPN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 83. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
UDP-galactopyranose mutase

Short name=UGM
EC=5.4.99.9
Alternative name(s):
UDP-GALP mutase
Uridine 5-diphosphate galactopyranose mutase
Gene names
Name:glf
Ordered Locus Names:MPN_278
ORF Names:MP557
OrganismMycoplasma pneumoniae (strain ATCC 29342 / M129) [Reference proteome] [HAMAP]
Taxonomic identifier272634 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length399 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the conversion of UDP-GalP into UDP-GalF through a 2-keto intermediate By similarity.

Catalytic activity

UDP-alpha-D-galactopyranose = UDP-alpha-D-galactofuranose.

Cofactor

FAD By similarity.

Sequence similarities

Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

Ontologies

Keywords
   LigandFAD
Flavoprotein
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionUDP-galactopyranose mutase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 399399UDP-galactopyranose mutase
PRO_0000087510

Regions

Nucleotide binding44 – 452FAD By similarity
Nucleotide binding71 – 722FAD By similarity
Nucleotide binding381 – 3866FAD By similarity

Sites

Binding site251FAD By similarity
Binding site521FAD; via amide nitrogen By similarity
Binding site1711UDP-GalP By similarity
Binding site1751UDP-GalP By similarity
Binding site2001UDP-GalP By similarity
Binding site2971UDP-GalP By similarity
Binding site3061UDP-GalP By similarity
Binding site3451UDP-GalP By similarity
Binding site3741FAD By similarity
Binding site3801UDP-GalP By similarity

Sequences

Sequence LengthMass (Da)Tools
P75499 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 53ED30655351639A

FASTA39945,910
        10         20         30         40         50         60 
MTLFSFPNYV NWNKFDFIVL GAGISGIVLS HVLAQHGKSV LLLEKRNQLG GNCYDKLDET 

        70         80         90        100        110        120 
TGLLFHQYGP HIFHTDNQKV MDFIQPFFEL NNYQHRVGLQ LDNNLDLTLP FDFSQMRKLL 

       130        140        150        160        170        180 
DTKTASSLIN FFQQHFPAEK HLTLMQLQTI NFAPVQQLYQ FLKIKVYGPY SVKMWGMPLE 

       190        200        210        220        230        240 
QIDPSVLGRV KISLSENSSY FPTATIQGLP KGGYTKAFTK MVDHPLIDLR LNCPANLISV 

       250        260        270        280        290        300 
NNNQLLFANQ PITKPVVYCG LIDQLFGYCF GRLQYRSLHF EWKRYAVKQH QAYPVMNWPL 

       310        320        330        340        350        360 
HPTITRQVEY KQLTQEGLES NQTIVSCETP GAFREGDPRF MEPYYPLNDV SNNALFARYL 

       370        380        390 
KLANAIPNIH LLGRLALYQY IDMDRAIAQS LAKAEQLLQ 

« Hide

References

[1]"Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29342 / M129.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U00089 Genomic DNA. Translation: AAB96205.1.
PIRS73883.
RefSeqNP_109966.1. NC_000912.1.

3D structure databases

ProteinModelPortalP75499.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActP75499. 2 interactions.
STRING272634.MPN278.

Proteomic databases

PaxDbP75499.
PRIDEP75499.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB96205; AAB96205; MPN_278.
GeneID876844.
KEGGmpn:MPN278.
PATRIC20021883. VBIMycPne110_0298.

Phylogenomic databases

eggNOGCOG0562.
KOK01854.
OMAKNEPYYP.
OrthoDBEOG62K1X2.
ProtClustDBCLSK542169.

Enzyme and pathway databases

BioCycMPNE272634:GJ6Z-285-MONOMER.

Family and domain databases

Gene3D3.40.50.720. 3 hits.
InterProIPR016040. NAD(P)-bd_dom.
IPR004379. UDP-GALP_mutase.
IPR015899. UDP-GalPyranose_mutase_C.
[Graphical view]
PANTHERPTHR21197. PTHR21197. 1 hit.
PfamPF03275. GLF. 1 hit.
[Graphical view]
TIGRFAMsTIGR00031. UDP-GALP_mutase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLF_MYCPN
AccessionPrimary (citable) accession number: P75499
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: April 16, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Mycoplasma pneumoniae

Mycoplasma pneumoniae (strain M129): entries and gene names