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P75451

- Y111_MYCPN

UniProt

P75451 - Y111_MYCPN

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Protein

Uncharacterized adenine-specific methylase MPN_111

Gene

MPN_111

Organism
Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine + DNA 6-methylaminopurine.

GO - Molecular functioni

  1. DNA binding Source: InterPro
  2. site-specific DNA-methyltransferase (adenine-specific) activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciMPNE272634:GJ6Z-117-MONOMER.

Protein family/group databases

REBASEi27679. MpnORF111P.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized adenine-specific methylase MPN_111 (EC:2.1.1.72)
Gene namesi
Ordered Locus Names:MPN_111
ORF Names:C09_orf422, MP043
OrganismiMycoplasma pneumoniae (strain ATCC 29342 / M129)
Taxonomic identifieri272634 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000808: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 422422Uncharacterized adenine-specific methylase MPN_111PRO_0000088017Add
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the N(4)/N(6)-methyltransferase family.Curated

Phylogenomic databases

eggNOGiCOG0827.
KOiK00571.
OrthoDBiEOG6HQSKB.

Family and domain databases

Gene3Di3.40.50.150. 2 hits.
InterProiIPR002052. DNA_methylase_N6_adenine_CS.
IPR011639. RM_methylase_Eco57I.
IPR029063. SAM-dependent_MTases-like.
[Graphical view]
PfamiPF07669. Eco57I. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 2 hits.
PROSITEiPS00092. N6_MTASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P75451-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNKNSGKDYE SIQGKIKSKA EIEDSVILDQ DTFQGKGEEK TKLDELIRWE
60 70 80 90 100
AEKNDLLKLI DNVGNDEVFT PVETCQRMLD ELFPEDHEVW SNPDLKWLNP
110 120 130 140 150
CDKNGVFFRE IALRLDKGLT KIIPDEYARK KHIMTKMLFS IGLTKFTSLM
160 170 180 190 200
VRRTLYYCIK ANKRKTSEDE GCAIANGARF NNEFGNVVTP YKEHYFGKES
210 220 230 240 250
KSKNCHFCGT NKNSKYVNSM TEEKYAYDFI HLNSDEYENY FKTNFGVMKF
260 270 280 290 300
DVIIGNPPYQ LSNGSGSDGN GAKAIFQDFV LKAIDLEPKY LAMIIPAKWM
310 320 330 340 350
ISAENIFLNL RDKLKKNKDI KEINIFFDSK DCFPKREIKG GICYFIWQNN
360 370 380 390 400
YQGKTLINTK FSKKGKSTEI DSSKRNLFVS VLNNTEQIIF RKRIWQDIYT
410 420
KIDSISASEM KNTHTEREQF RS
Length:422
Mass (Da):49,062
Last modified:February 1, 1997 - v1
Checksum:iC0AB9D9E4230BA81
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00089 Genomic DNA. Translation: AAB95691.1.
PIRiS73369.
RefSeqiNP_109799.1. NC_000912.1.

Genome annotation databases

EnsemblBacteriaiAAB95691; AAB95691; MPN_111.
GeneIDi877256.
KEGGimpn:MPN111.
PATRICi20021521. VBIMycPne110_0118.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00089 Genomic DNA. Translation: AAB95691.1 .
PIRi S73369.
RefSeqi NP_109799.1. NC_000912.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein family/group databases

REBASEi 27679. MpnORF111P.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAB95691 ; AAB95691 ; MPN_111 .
GeneIDi 877256.
KEGGi mpn:MPN111.
PATRICi 20021521. VBIMycPne110_0118.

Phylogenomic databases

eggNOGi COG0827.
KOi K00571.
OrthoDBi EOG6HQSKB.

Enzyme and pathway databases

BioCyci MPNE272634:GJ6Z-117-MONOMER.

Family and domain databases

Gene3Di 3.40.50.150. 2 hits.
InterProi IPR002052. DNA_methylase_N6_adenine_CS.
IPR011639. RM_methylase_Eco57I.
IPR029063. SAM-dependent_MTases-like.
[Graphical view ]
Pfami PF07669. Eco57I. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 2 hits.
PROSITEi PS00092. N6_MTASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
    Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
    Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29342 / M129.

Entry informationi

Entry nameiY111_MYCPN
AccessioniPrimary (citable) accession number: P75451
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: February 1, 1997
Last modified: October 1, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Mycoplasma pneumoniae
    Mycoplasma pneumoniae (strain M129): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3