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P75451

- Y111_MYCPN

UniProt

P75451 - Y111_MYCPN

Protein

Uncharacterized adenine-specific methylase MPN_111

Gene

MPN_111

Organism
Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 80 (01 Oct 2014)
      Sequence version 1 (01 Feb 1997)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine + DNA 6-methylaminopurine.

    GO - Molecular functioni

    1. DNA binding Source: InterPro
    2. site-specific DNA-methyltransferase (adenine-specific) activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Methyltransferase, Transferase

    Keywords - Ligandi

    S-adenosyl-L-methionine

    Enzyme and pathway databases

    BioCyciMPNE272634:GJ6Z-117-MONOMER.

    Protein family/group databases

    REBASEi27679. MpnORF111P.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uncharacterized adenine-specific methylase MPN_111 (EC:2.1.1.72)
    Gene namesi
    Ordered Locus Names:MPN_111
    ORF Names:C09_orf422, MP043
    OrganismiMycoplasma pneumoniae (strain ATCC 29342 / M129)
    Taxonomic identifieri272634 [NCBI]
    Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
    ProteomesiUP000000808: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 422422Uncharacterized adenine-specific methylase MPN_111PRO_0000088017Add
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the N(4)/N(6)-methyltransferase family.Curated

    Phylogenomic databases

    eggNOGiCOG0827.
    KOiK00571.
    OrthoDBiEOG6HQSKB.

    Family and domain databases

    Gene3Di3.40.50.150. 2 hits.
    InterProiIPR002052. DNA_methylase_N6_adenine_CS.
    IPR011639. RM_methylase_Eco57I.
    IPR029063. SAM-dependent_MTases-like.
    [Graphical view]
    PfamiPF07669. Eco57I. 1 hit.
    [Graphical view]
    SUPFAMiSSF53335. SSF53335. 2 hits.
    PROSITEiPS00092. N6_MTASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P75451-1 [UniParc]FASTAAdd to Basket

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    MNKNSGKDYE SIQGKIKSKA EIEDSVILDQ DTFQGKGEEK TKLDELIRWE    50
    AEKNDLLKLI DNVGNDEVFT PVETCQRMLD ELFPEDHEVW SNPDLKWLNP 100
    CDKNGVFFRE IALRLDKGLT KIIPDEYARK KHIMTKMLFS IGLTKFTSLM 150
    VRRTLYYCIK ANKRKTSEDE GCAIANGARF NNEFGNVVTP YKEHYFGKES 200
    KSKNCHFCGT NKNSKYVNSM TEEKYAYDFI HLNSDEYENY FKTNFGVMKF 250
    DVIIGNPPYQ LSNGSGSDGN GAKAIFQDFV LKAIDLEPKY LAMIIPAKWM 300
    ISAENIFLNL RDKLKKNKDI KEINIFFDSK DCFPKREIKG GICYFIWQNN 350
    YQGKTLINTK FSKKGKSTEI DSSKRNLFVS VLNNTEQIIF RKRIWQDIYT 400
    KIDSISASEM KNTHTEREQF RS 422
    Length:422
    Mass (Da):49,062
    Last modified:February 1, 1997 - v1
    Checksum:iC0AB9D9E4230BA81
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00089 Genomic DNA. Translation: AAB95691.1.
    PIRiS73369.
    RefSeqiNP_109799.1. NC_000912.1.

    Genome annotation databases

    EnsemblBacteriaiAAB95691; AAB95691; MPN_111.
    GeneIDi877256.
    KEGGimpn:MPN111.
    PATRICi20021521. VBIMycPne110_0118.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00089 Genomic DNA. Translation: AAB95691.1 .
    PIRi S73369.
    RefSeqi NP_109799.1. NC_000912.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    REBASEi 27679. MpnORF111P.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAB95691 ; AAB95691 ; MPN_111 .
    GeneIDi 877256.
    KEGGi mpn:MPN111.
    PATRICi 20021521. VBIMycPne110_0118.

    Phylogenomic databases

    eggNOGi COG0827.
    KOi K00571.
    OrthoDBi EOG6HQSKB.

    Enzyme and pathway databases

    BioCyci MPNE272634:GJ6Z-117-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.150. 2 hits.
    InterProi IPR002052. DNA_methylase_N6_adenine_CS.
    IPR011639. RM_methylase_Eco57I.
    IPR029063. SAM-dependent_MTases-like.
    [Graphical view ]
    Pfami PF07669. Eco57I. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53335. SSF53335. 2 hits.
    PROSITEi PS00092. N6_MTASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
      Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
      Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 29342 / M129.

    Entry informationi

    Entry nameiY111_MYCPN
    AccessioniPrimary (citable) accession number: P75451
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 10, 2002
    Last sequence update: February 1, 1997
    Last modified: October 1, 2014
    This is version 80 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Mycoplasma pneumoniae
      Mycoplasma pneumoniae (strain M129): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3