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Protein

Putative type-1 restriction enzyme MpnORFDP R protein part 2

Gene

MPN_345

Organism
Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Subunit R is required for both nuclease and ATPase activities, but not for modification.By similarity

Catalytic activityi

Endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5'-phosphates; ATP is simultaneously hydrolyzed.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Restriction system

Keywords - Ligandi

ATP-binding, DNA-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMPNE272634:GJ6Z-362-MONOMER.

Protein family/group databases

REBASEi6705. MpnIIP.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative type-1 restriction enzyme MpnORFDP R protein part 2 (EC:3.1.21.3)
Alternative name(s):
MpnORFDBP
Putative type I restriction enzyme MpnORFDP R protein part 2
Gene namesi
Ordered Locus Names:MPN_345
ORF Names:H91_orf206, MP491
OrganismiMycoplasma pneumoniae (strain ATCC 29342 / M129)
Taxonomic identifieri272634 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000808 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 206206Putative type-1 restriction enzyme MpnORFDP R protein part 2PRO_0000077264Add
BLAST

Interactioni

Subunit structurei

The type I restriction/modification system is composed of three polypeptides R, M and S.By similarity

Protein-protein interaction databases

STRINGi272634.MPN345.

Structurei

3D structure databases

ProteinModelPortaliP75433.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0610.
OrthoDBiEOG6JTCB4.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR006935. Helicase/UvrB_dom.
IPR014001. Helicase_ATP-bd.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF04851. ResIII. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

P75433-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRWSDSENNK IDYIEDFATH FLNKNALLNV ICKFCVFRSN SDLWVMRPYQ
60 70 80 90 100
ICATERILEK IKEDNRNSKN SKNASKGGCI WHSTGSGKTL TSFKAVQLAS
110 120 130 140 150
EIDFVDKVLF VVDRKDLDNQ TIEEYEKFQA GSVSETENTN DLKEKILDDS
160 170 180 190 200
TATRAIVTTI HKLKRLIDQR SKLKDEDLKK KNIVLIFDEC HRSQFGKMKQ

EIDEFF
Length:206
Mass (Da):23,957
Last modified:February 1, 1997 - v1
Checksum:iE69EB18CF7185F20
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00089 Genomic DNA. Translation: AAB96139.1.
PIRiS73817.

Genome annotation databases

EnsemblBacteriaiAAB96139; AAB96139; MPN_345.
PATRICi20022046. VBIMycPne110_0370.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00089 Genomic DNA. Translation: AAB96139.1.
PIRiS73817.

3D structure databases

ProteinModelPortaliP75433.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272634.MPN345.

Protein family/group databases

REBASEi6705. MpnIIP.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB96139; AAB96139; MPN_345.
PATRICi20022046. VBIMycPne110_0370.

Phylogenomic databases

eggNOGiCOG0610.
OrthoDBiEOG6JTCB4.

Enzyme and pathway databases

BioCyciMPNE272634:GJ6Z-362-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR006935. Helicase/UvrB_dom.
IPR014001. Helicase_ATP-bd.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF04851. ResIII. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
    Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
    Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29342 / M129.

Entry informationi

Entry nameiT1RY_MYCPN
AccessioniPrimary (citable) accession number: P75433
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: February 1, 1997
Last modified: January 7, 2015
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Mycoplasma pneumoniae
    Mycoplasma pneumoniae (strain M129): entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.