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P75431

- T1RX_MYCPN

UniProt

P75431 - T1RX_MYCPN

Protein

Putative type I restriction enzyme MpnORFDP R protein part 1

Gene

MPN_347

Organism
Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 72 (01 Oct 2014)
      Sequence version 1 (01 Feb 1997)
      Previous versions | rss
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    Functioni

    Subunit R is required for both nuclease and ATPase activities, but not for modification.By similarity

    Catalytic activityi

    Endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5'-phosphates; ATP is simultaneously hydrolyzed.

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: UniProtKB-KW
    3. Type I site-specific deoxyribonuclease activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA restriction-modification system Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Restriction system

    Keywords - Ligandi

    ATP-binding, DNA-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciMPNE272634:GJ6Z-364-MONOMER.

    Protein family/group databases

    REBASEi6705. MpnIIP.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative type I restriction enzyme MpnORFDP R protein part 1 (EC:3.1.21.3)
    Alternative name(s):
    MpnORFDAP
    Gene namesi
    Ordered Locus Names:MPN_347
    ORF Names:H91_orf376, MP489
    OrganismiMycoplasma pneumoniae (strain ATCC 29342 / M129)
    Taxonomic identifieri272634 [NCBI]
    Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
    ProteomesiUP000000808: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 376376Putative type I restriction enzyme MpnORFDP R protein part 1PRO_0000077263Add
    BLAST

    Interactioni

    Subunit structurei

    The type I restriction/modification system is composed of three polypeptides R, M and S.By similarity

    Protein-protein interaction databases

    IntActiP75431. 1 interaction.
    STRINGi272634.MPN347.

    Structurei

    3D structure databases

    ProteinModelPortaliP75431.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiCOG0610.
    KOiK01153.
    OMAiFRDIREN.
    OrthoDBiEOG6JTCB4.

    Family and domain databases

    InterProiIPR022625. TypeI_RM_Rsu_C.
    [Graphical view]
    PfamiPF12008. EcoR124_C. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P75431-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFLTGFDAPT LNTLWVDKNL SEHTLIQAFS RTNRCFGETK KFGNIFSFRD    50
    IRENFDQALK MYADKRGLKD IKSNMVMREF EEVFEKFKDW TEKIKQKYPN 100
    PDEILNLEKE EKWDFSDLFG EFLGDYRTVK SYHEFDKDNP YLPSDEFNKY 150
    FAAFSQIQEE IRKEKAEKKA LEVQEEDLSN EVRKEPQIFS WEYGEGIQAN 200
    LDYIFHLIKD LYNCDNEQDR QKVLDKIKTA IRTNPEIQVN EDILNEFIED 250
    LGKSFEKEKL EEVWKTEGKL RECLKDFCKK KEESNKKKII NDFLVKGVFL 300
    VEWVADKQLN TAKKKGEYSP SWSDTEKLIW KEKSTNLPTM TEKDEDGNFK 350
    WRKLITDISE AFKNHFERFI RFVEIR 376
    Length:376
    Mass (Da):45,087
    Last modified:February 1, 1997 - v1
    Checksum:i691BB674F64988D9
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00089 Genomic DNA. Translation: AAB96137.1.
    PIRiS73815.
    RefSeqiNP_110035.1. NC_000912.1.
    WP_010874703.1. NC_000912.1.

    Genome annotation databases

    EnsemblBacteriaiAAB96137; AAB96137; MPN_347.
    GeneIDi876766.
    KEGGimpn:MPN347.
    PATRICi20022050. VBIMycPne110_0372.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00089 Genomic DNA. Translation: AAB96137.1 .
    PIRi S73815.
    RefSeqi NP_110035.1. NC_000912.1.
    WP_010874703.1. NC_000912.1.

    3D structure databases

    ProteinModelPortali P75431.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi P75431. 1 interaction.
    STRINGi 272634.MPN347.

    Protein family/group databases

    REBASEi 6705. MpnIIP.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAB96137 ; AAB96137 ; MPN_347 .
    GeneIDi 876766.
    KEGGi mpn:MPN347.
    PATRICi 20022050. VBIMycPne110_0372.

    Phylogenomic databases

    eggNOGi COG0610.
    KOi K01153.
    OMAi FRDIREN.
    OrthoDBi EOG6JTCB4.

    Enzyme and pathway databases

    BioCyci MPNE272634:GJ6Z-364-MONOMER.

    Family and domain databases

    InterProi IPR022625. TypeI_RM_Rsu_C.
    [Graphical view ]
    Pfami PF12008. EcoR124_C. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
      Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
      Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 29342 / M129.

    Entry informationi

    Entry nameiT1RX_MYCPN
    AccessioniPrimary (citable) accession number: P75431
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 2000
    Last sequence update: February 1, 1997
    Last modified: October 1, 2014
    This is version 72 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Mycoplasma pneumoniae
      Mycoplasma pneumoniae (strain M129): entries and gene names

    External Data

    Dasty 3