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P75431 (T1RX_MYCPN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative type I restriction enzyme MpnORFDP R protein part 1

EC=3.1.21.3
Alternative name(s):
MpnORFDAP
Gene names
Ordered Locus Names:MPN_347
ORF Names:H91_orf376, MP489
OrganismMycoplasma pneumoniae (strain ATCC 29342 / M129) [Reference proteome] [HAMAP]
Taxonomic identifier272634 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length376 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunit R is required for both nuclease and ATPase activities, but not for modification By similarity.

Catalytic activity

Endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5'-phosphates; ATP is simultaneously hydrolyzed.

Subunit structure

The type I restriction/modification system is composed of three polypeptides R, M and S By similarity.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 376376Putative type I restriction enzyme MpnORFDP R protein part 1
PRO_0000077263

Sequences

Sequence LengthMass (Da)Tools
P75431 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 691BB674F64988D9

FASTA37645,087
        10         20         30         40         50         60 
MFLTGFDAPT LNTLWVDKNL SEHTLIQAFS RTNRCFGETK KFGNIFSFRD IRENFDQALK 

        70         80         90        100        110        120 
MYADKRGLKD IKSNMVMREF EEVFEKFKDW TEKIKQKYPN PDEILNLEKE EKWDFSDLFG 

       130        140        150        160        170        180 
EFLGDYRTVK SYHEFDKDNP YLPSDEFNKY FAAFSQIQEE IRKEKAEKKA LEVQEEDLSN 

       190        200        210        220        230        240 
EVRKEPQIFS WEYGEGIQAN LDYIFHLIKD LYNCDNEQDR QKVLDKIKTA IRTNPEIQVN 

       250        260        270        280        290        300 
EDILNEFIED LGKSFEKEKL EEVWKTEGKL RECLKDFCKK KEESNKKKII NDFLVKGVFL 

       310        320        330        340        350        360 
VEWVADKQLN TAKKKGEYSP SWSDTEKLIW KEKSTNLPTM TEKDEDGNFK WRKLITDISE 

       370 
AFKNHFERFI RFVEIR 

« Hide

References

[1]"Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29342 / M129.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U00089 Genomic DNA. Translation: AAB96137.1.
PIRS73815.
RefSeqNP_110035.1. NC_000912.1.

3D structure databases

ProteinModelPortalP75431.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActP75431. 1 interaction.
STRING272634.MPN347.

Protein family/group databases

REBASE6705. MpnIIP.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB96137; AAB96137; MPN_347.
GeneID876766.
KEGGmpn:MPN347.
PATRIC20022050. VBIMycPne110_0372.

Phylogenomic databases

eggNOGCOG0610.
KOK01153.
OMAFRDIREN.
OrthoDBEOG6JTCB4.

Enzyme and pathway databases

BioCycMPNE272634:GJ6Z-364-MONOMER.

Family and domain databases

InterProIPR022625. TypeI_RM_Rsu_C.
[Graphical view]
PfamPF12008. EcoR124_C. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameT1RX_MYCPN
AccessionPrimary (citable) accession number: P75431
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: February 1, 1997
Last modified: May 14, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Mycoplasma pneumoniae

Mycoplasma pneumoniae (strain M129): entries and gene names