SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P75431

- T1RX_MYCPN

UniProt

P75431 - T1RX_MYCPN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Putative type I restriction enzyme MpnORFDP R protein part 1
Gene
MPN_347, H91_orf376, MP489
Organism
Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Subunit R is required for both nuclease and ATPase activities, but not for modification By similarity.

Catalytic activityi

Endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5'-phosphates; ATP is simultaneously hydrolyzed.

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: UniProtKB-KW
  3. Type I site-specific deoxyribonuclease activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA restriction-modification system Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Restriction system

Keywords - Ligandi

ATP-binding, DNA-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMPNE272634:GJ6Z-364-MONOMER.

Protein family/group databases

REBASEi6705. MpnIIP.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative type I restriction enzyme MpnORFDP R protein part 1 (EC:3.1.21.3)
Alternative name(s):
MpnORFDAP
Gene namesi
Ordered Locus Names:MPN_347
ORF Names:H91_orf376, MP489
OrganismiMycoplasma pneumoniae (strain ATCC 29342 / M129)
Taxonomic identifieri272634 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000808: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 376376Putative type I restriction enzyme MpnORFDP R protein part 1
PRO_0000077263Add
BLAST

Interactioni

Subunit structurei

The type I restriction/modification system is composed of three polypeptides R, M and S By similarity.

Protein-protein interaction databases

IntActiP75431. 1 interaction.
STRINGi272634.MPN347.

Structurei

3D structure databases

ProteinModelPortaliP75431.

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0610.
KOiK01153.
OMAiFRDIREN.
OrthoDBiEOG6JTCB4.

Family and domain databases

InterProiIPR022625. TypeI_RM_Rsu_C.
[Graphical view]
PfamiPF12008. EcoR124_C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P75431-1 [UniParc]FASTAAdd to Basket

« Hide

MFLTGFDAPT LNTLWVDKNL SEHTLIQAFS RTNRCFGETK KFGNIFSFRD    50
IRENFDQALK MYADKRGLKD IKSNMVMREF EEVFEKFKDW TEKIKQKYPN 100
PDEILNLEKE EKWDFSDLFG EFLGDYRTVK SYHEFDKDNP YLPSDEFNKY 150
FAAFSQIQEE IRKEKAEKKA LEVQEEDLSN EVRKEPQIFS WEYGEGIQAN 200
LDYIFHLIKD LYNCDNEQDR QKVLDKIKTA IRTNPEIQVN EDILNEFIED 250
LGKSFEKEKL EEVWKTEGKL RECLKDFCKK KEESNKKKII NDFLVKGVFL 300
VEWVADKQLN TAKKKGEYSP SWSDTEKLIW KEKSTNLPTM TEKDEDGNFK 350
WRKLITDISE AFKNHFERFI RFVEIR 376
Length:376
Mass (Da):45,087
Last modified:February 1, 1997 - v1
Checksum:i691BB674F64988D9
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00089 Genomic DNA. Translation: AAB96137.1.
PIRiS73815.
RefSeqiNP_110035.1. NC_000912.1.
WP_010874703.1. NC_000912.1.

Genome annotation databases

EnsemblBacteriaiAAB96137; AAB96137; MPN_347.
GeneIDi876766.
KEGGimpn:MPN347.
PATRICi20022050. VBIMycPne110_0372.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00089 Genomic DNA. Translation: AAB96137.1 .
PIRi S73815.
RefSeqi NP_110035.1. NC_000912.1.
WP_010874703.1. NC_000912.1.

3D structure databases

ProteinModelPortali P75431.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi P75431. 1 interaction.
STRINGi 272634.MPN347.

Protein family/group databases

REBASEi 6705. MpnIIP.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAB96137 ; AAB96137 ; MPN_347 .
GeneIDi 876766.
KEGGi mpn:MPN347.
PATRICi 20022050. VBIMycPne110_0372.

Phylogenomic databases

eggNOGi COG0610.
KOi K01153.
OMAi FRDIREN.
OrthoDBi EOG6JTCB4.

Enzyme and pathway databases

BioCyci MPNE272634:GJ6Z-364-MONOMER.

Family and domain databases

InterProi IPR022625. TypeI_RM_Rsu_C.
[Graphical view ]
Pfami PF12008. EcoR124_C. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
    Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
    Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29342 / M129.

Entry informationi

Entry nameiT1RX_MYCPN
AccessioniPrimary (citable) accession number: P75431
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: February 1, 1997
Last modified: September 3, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Mycoplasma pneumoniae
    Mycoplasma pneumoniae (strain M129): entries and gene names

External Data

Dasty 3

Similar proteinsi