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Protein

Putative type I restriction enzyme MpnORFDP R protein part 1

Gene

MPN_347

Organism
Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Subunit R is required for both nuclease and ATPase activities, but not for modification.By similarity

Catalytic activityi

Endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5'-phosphates; ATP is simultaneously hydrolyzed.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding, Hydrolase
Biological processRestriction system
LigandATP-binding, Nucleotide-binding

Protein family/group databases

REBASEi6705. MpnIIP.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative type I restriction enzyme MpnORFDP R protein part 1 (EC:3.1.21.3)
Alternative name(s):
MpnORFDAP
Gene namesi
Ordered Locus Names:MPN_347
ORF Names:H91_orf376, MP489
OrganismiMycoplasma pneumoniae (strain ATCC 29342 / M129)
Taxonomic identifieri272634 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
Proteomesi
  • UP000000808 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000772631 – 376Putative type I restriction enzyme MpnORFDP R protein part 1Add BLAST376

Interactioni

Subunit structurei

The type I restriction/modification system is composed of three polypeptides R, M and S.By similarity

Protein-protein interaction databases

IntActiP75431. 1 interactor.

Structurei

3D structure databases

ProteinModelPortaliP75431.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

OMAiIQVNEDI.

Family and domain databases

InterProiView protein in InterPro
IPR022625. TypeI_RM_Rsu_C.
PfamiView protein in Pfam
PF12008. EcoR124_C. 1 hit.

Sequencei

Sequence statusi: Complete.

P75431-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFLTGFDAPT LNTLWVDKNL SEHTLIQAFS RTNRCFGETK KFGNIFSFRD
60 70 80 90 100
IRENFDQALK MYADKRGLKD IKSNMVMREF EEVFEKFKDW TEKIKQKYPN
110 120 130 140 150
PDEILNLEKE EKWDFSDLFG EFLGDYRTVK SYHEFDKDNP YLPSDEFNKY
160 170 180 190 200
FAAFSQIQEE IRKEKAEKKA LEVQEEDLSN EVRKEPQIFS WEYGEGIQAN
210 220 230 240 250
LDYIFHLIKD LYNCDNEQDR QKVLDKIKTA IRTNPEIQVN EDILNEFIED
260 270 280 290 300
LGKSFEKEKL EEVWKTEGKL RECLKDFCKK KEESNKKKII NDFLVKGVFL
310 320 330 340 350
VEWVADKQLN TAKKKGEYSP SWSDTEKLIW KEKSTNLPTM TEKDEDGNFK
360 370
WRKLITDISE AFKNHFERFI RFVEIR
Length:376
Mass (Da):45,087
Last modified:February 1, 1997 - v1
Checksum:i691BB674F64988D9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00089 Genomic DNA. Translation: AAB96137.1.
PIRiS73815.

Genome annotation databases

EnsemblBacteriaiAAB96137; AAB96137; MPN_347.

Similar proteinsi

Entry informationi

Entry nameiT1RX_MYCPN
AccessioniPrimary (citable) accession number: P75431
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: February 1, 1997
Last modified: August 30, 2017
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Mycoplasma pneumoniae
    Mycoplasma pneumoniae (strain M129): entries and gene names