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P75400

- COAE_MYCPN

UniProt

P75400 - COAE_MYCPN

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Protein

Dephospho-CoA kinase

Gene
coaE, MPN_382, MP455
Organism
Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A By similarity.UniRule annotation

Catalytic activityi

ATP + 3'-dephospho-CoA = ADP + CoA.UniRule annotation

Pathwayi

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi7 – 148ATP Reviewed prediction

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. dephospho-CoA kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. coenzyme A biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Coenzyme A biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciMPNE272634:GJ6Z-403-MONOMER.
UniPathwayiUPA00241; UER00356.

Names & Taxonomyi

Protein namesi
Recommended name:
Dephospho-CoA kinase (EC:2.7.1.24)
Alternative name(s):
Dephosphocoenzyme A kinase
Gene namesi
Name:coaE
Ordered Locus Names:MPN_382
ORF Names:MP455
OrganismiMycoplasma pneumoniae (strain ATCC 29342 / M129)
Taxonomic identifieri272634 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000808: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 200200Dephospho-CoA kinaseUniRule annotationPRO_0000172962Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272634.MPN382.

Structurei

3D structure databases

ProteinModelPortaliP75400.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 200199DPCKAdd
BLAST

Sequence similaritiesi

Belongs to the CoaE family.

Phylogenomic databases

eggNOGiCOG0237.
KOiK00859.
OMAiAVMLNYW.
OrthoDBiEOG6TR0JH.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00376. Dephospho_CoA_kinase.
InterProiIPR001977. Depp_CoAkinase.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF01121. CoaE. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00152. TIGR00152. 1 hit.
PROSITEiPS51219. DPCK. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P75400-1 [UniParc]FASTAAdd to Basket

« Hide

MLIAVVGKAG VGKTTVLQYI ADYFHFPVFF ADRFIHQQYA NGQAGYAIVK    50
QQFGAQFVNH EAVDRKQLAQ YVFNQPDELK RLSNLTKPLV QEWLNQLKAQ 100
FQDKIALVEI AVMLNYWNDY RPFFDEVIQI ERDAKIVKQA LKARGVDVEQ 150
VQKLIADPTY PILTVINNST VAECALHVTQ FLESIAKSDK CHHGHYQTPK 200
Length:200
Mass (Da):22,910
Last modified:February 1, 1997 - v1
Checksum:i396EA0C4AA940589
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00089 Genomic DNA. Translation: AAB96103.1.
PIRiS73781.
RefSeqiNP_110070.1. NC_000912.1.

Genome annotation databases

EnsemblBacteriaiAAB96103; AAB96103; MPN_382.
GeneIDi877392.
KEGGimpn:MPN382.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00089 Genomic DNA. Translation: AAB96103.1 .
PIRi S73781.
RefSeqi NP_110070.1. NC_000912.1.

3D structure databases

ProteinModelPortali P75400.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272634.MPN382.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAB96103 ; AAB96103 ; MPN_382 .
GeneIDi 877392.
KEGGi mpn:MPN382.

Phylogenomic databases

eggNOGi COG0237.
KOi K00859.
OMAi AVMLNYW.
OrthoDBi EOG6TR0JH.

Enzyme and pathway databases

UniPathwayi UPA00241 ; UER00356 .
BioCyci MPNE272634:GJ6Z-403-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_00376. Dephospho_CoA_kinase.
InterProi IPR001977. Depp_CoAkinase.
IPR027417. P-loop_NTPase.
[Graphical view ]
Pfami PF01121. CoaE. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00152. TIGR00152. 1 hit.
PROSITEi PS51219. DPCK. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
    Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
    Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29342 / M129.

Entry informationi

Entry nameiCOAE_MYCPN
AccessioniPrimary (citable) accession number: P75400
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: May 14, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Mycoplasma pneumoniae
    Mycoplasma pneumoniae (strain M129): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi