Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P75400 (COAE_MYCPN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 89. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Dephospho-CoA kinase

EC=2.7.1.24
Alternative name(s):
Dephosphocoenzyme A kinase
Gene names
Name:coaE
Ordered Locus Names:MPN_382
ORF Names:MP455
OrganismMycoplasma pneumoniae (strain ATCC 29342 / M129) [Reference proteome] [HAMAP]
Taxonomic identifier272634 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length200 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A By similarity. HAMAP-Rule MF_00376

Catalytic activity

ATP + 3'-dephospho-CoA = ADP + CoA. HAMAP-Rule MF_00376

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 5/5. HAMAP-Rule MF_00376

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00376.

Sequence similarities

Belongs to the CoaE family.

Contains 1 DPCK (dephospho-CoA kinase) domain.

Ontologies

Keywords
   Biological processCoenzyme A biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcoenzyme A biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

dephospho-CoA kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 200200Dephospho-CoA kinase HAMAP-Rule MF_00376
PRO_0000172962

Regions

Domain2 – 200199DPCK
Nucleotide binding7 – 148ATP Potential

Sequences

Sequence LengthMass (Da)Tools
P75400 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 396EA0C4AA940589

FASTA20022,910
        10         20         30         40         50         60 
MLIAVVGKAG VGKTTVLQYI ADYFHFPVFF ADRFIHQQYA NGQAGYAIVK QQFGAQFVNH 

        70         80         90        100        110        120 
EAVDRKQLAQ YVFNQPDELK RLSNLTKPLV QEWLNQLKAQ FQDKIALVEI AVMLNYWNDY 

       130        140        150        160        170        180 
RPFFDEVIQI ERDAKIVKQA LKARGVDVEQ VQKLIADPTY PILTVINNST VAECALHVTQ 

       190        200 
FLESIAKSDK CHHGHYQTPK 

« Hide

References

[1]"Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29342 / M129.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U00089 Genomic DNA. Translation: AAB96103.1.
PIRS73781.
RefSeqNP_110070.1. NC_000912.1.

3D structure databases

ProteinModelPortalP75400.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272634.MPN382.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB96103; AAB96103; MPN_382.
GeneID877392.
KEGGmpn:MPN382.

Phylogenomic databases

eggNOGCOG0237.
KOK00859.
OMAAVMLNYW.
OrthoDBEOG6TR0JH.

Enzyme and pathway databases

BioCycMPNE272634:GJ6Z-403-MONOMER.
UniPathwayUPA00241; UER00356.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_00376. Dephospho_CoA_kinase.
InterProIPR001977. Depp_CoAkinase.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamPF01121. CoaE. 1 hit.
[Graphical view]
SUPFAMSSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00152. TIGR00152. 1 hit.
PROSITEPS51219. DPCK. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOAE_MYCPN
AccessionPrimary (citable) accession number: P75400
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: May 14, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Mycoplasma pneumoniae

Mycoplasma pneumoniae (strain M129): entries and gene names