P75387 (Y396_MYCPN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized protein MG277 homolog

Gene names

Ordered Locus Names:	MPN_396
ORF Names:	F11_orf887, MP442

Organism

Mycoplasma pneumoniae (strain ATCC 29342 / M129) [Reference proteome] [HAMAP]

Taxonomic identifier

272634 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Tenericutes › Mollicutes › Mycoplasmatales › Mycoplasmataceae › Mycoplasma › Mycoplasma pneumoniae

Protein attributes

Sequence length	971 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Subcellular location

Cell membrane; Multi-pass membrane protein Potential.

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 971	971	Uncharacterized protein MG277 homolog		PRO_0000210503
Regions
	Transmembrane	11 – 31	21	Helical; Potential
	Transmembrane	516 – 536	21	Helical; Potential
	Transmembrane	547 – 567	21	Helical; Potential
	Transmembrane	569 – 589	21	Helical; Potential
	Transmembrane	615 – 635	21	Helical; Potential
	Transmembrane	651 – 671	21	Helical; Potential
	Transmembrane	727 – 747	21	Helical; Potential
	Transmembrane	763 – 783	21	Helical; Potential
	Transmembrane	795 – 815	21	Helical; Potential
	Transmembrane	817 – 837	21	Helical; Potential
	Transmembrane	878 – 898	21	Helical; Potential
	Transmembrane	900 – 920	21	Helical; Potential
	Transmembrane	923 – 943	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	P75387 [UniParc]. Last modified May 4, 2001. Version 2. Checksum: 3B5D96DC58108B96	FASTA	971	108,245
	10 20 30 40 50 60 MGLKKRVSFD WLLKIGIILV LAFLGLFGII FGSYKLLNDS RLGVVFNGST TTTVYFLNHK 70 80 90 100 110 120 SKDANKELDP TQKKDGNGSG NNTEMITDVN GFLNNIEKSY ANSLYAQGFS SVNITKNSHD 130 140 150 160 170 180 TSAKELSDKG VFDSSWLVND GLPSISVTFE QRREEARTRA RKRQIDAQVK RNALSAIEHN 190 200 210 220 230 240 YKLSLETTDG IVLFDSFDKE FIRNSLTAVV PQTTNTNSAL TFEYKLSKNV ITKESLHNDF 250 260 270 280 290 300 LDFIKSKSLT DSDYNTGNGQ KSVEGSGKWF KDKANGSAQN GNKTLVLWKD KEGAVQYVRN 310 320 330 340 350 360 IFNVPKGGTD YLTFNEREKN LWDFLHAEGN FSSGDNLFLQ KNNNGNSPIT KASDITLKNI 370 380 390 400 410 420 YYIYAAPTHF SQVATKDNNN KDAADVVAVA NSADTRKLRS GDATGFSGLF SNYILAEIRT 430 440 450 460 470 480 EDPVAKNGDP VKVNATLQSF LDSNNQRLEH GGNIKFQVAN FVNNDGSYVP ASYLEASRVK 490 500 510 520 530 540 VLLSNGFPET ATIAAANTKL VNAPLSNTLA RDVSNFASSF IALGVIILLA TIALGIRYKL 550 560 570 580 590 600 LGLYKALALA LSAISSLAFF SAVGGVVDVF SFVGIFFVVA VNIINLITLA ELFLRNIKNN 610 620 630 640 650 660 ASIVESWKLC LKRSFFTMIE THICWLLSAL VVIYLSNYQV QQLGTLMAVS AITSYFLNYG 670 680 690 700 710 720 LGVILVWLFV SSHSGLEWRF FLYKKDAQAL TKTSSNYSIL TENNDIQTDF FISKNQHDFF 730 740 750 760 770 780 GKKKWSLLFI WLTVLAFGVV MLGLYLGAPQ LLGNFLAADI ESSTGIMLGV GVISLLYLLY 790 800 810 820 830 840 SLPRYGVAYG ISYLIALILL AAGLFGAMYL ANFIFRIDQS TIQLIIFVYL FWLFFQARIG 850 860 870 880 890 900 QTTIWTYCYW FKRSLKDRVF VKNLFNDNVN SQWRLDLIGS SVLILLFIVY AAFNFGGING 910 920 930 940 950 960 TINLVIFYLI AIVALFSVFV NGLPLFSFGL INGWLSPYNY VQIHITLRHK KQMFKEVDQI 970 EEQLISGINS F

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae." Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R. Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29342 / M129.
[2]	"Re-annotating the Mycoplasma pneumoniae genome sequence: adding value, function and reading frames." Dandekar T., Huynen M., Regula J.T., Ueberle B., Zimmermann C.U., Andrade M.A., Doerks T., Sanchez-Pulido L., Snel B., Suyama M., Yuan Y.P., Herrmann R., Bork P. Nucleic Acids Res. 28:3278-3288(2000) [PubMed] [Europe PMC] [Abstract] Cited for: SEQUENCE REVISION. Strain: ATCC 29342 / M129.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U00089 Genomic DNA. Translation: AAG34750.1.
PIR	S73768.
RefSeq	NP_110084.1. NC_000912.1.
3D structure databases
ProteinModelPortal	P75387.
ModBase	Search...
Protein-protein interaction databases
STRING	272634.MPN396.
Proteomic databases
PaxDb	P75387.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAG34750; AAG34750; MPN_396.
GeneID	877104.
KEGG	mpn:MPN396.
PATRIC	20022168. VBIMycPne110_0427.
Phylogenomic databases
eggNOG	NOG12793.
KO	K12257.
OMA	NYVRNIF.
ProtClustDB	CLSK858636.
Enzyme and pathway databases
BioCyc	MPNE272634:GJ6Z-419-MONOMER.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

Y396_MYCPN

Accession

Primary (citable) accession number: P75387

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	May 4, 2001
Last modified:	May 1, 2013
This is version 68 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program