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P75360 (Y427_MYCPN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative phosphatase MPN_427

EC=3.1.3.-
Gene names
Ordered Locus Names:MPN_427
ORF Names:A05_orf290, MP414
OrganismMycoplasma pneumoniae (strain ATCC 29342 / M129) [Reference proteome] [HAMAP]
Taxonomic identifier272634 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length290 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Cofactor

Magnesium By similarity.

Sequence similarities

Belongs to the HAD-like hydrolase superfamily. Cof family.

Ontologies

Keywords
   LigandMagnesium
Metal-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionhydrolase activity

Inferred from electronic annotation. Source: UniProtKB-KW

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Binary interactions

With

Entry

#Exp.

IntAct

Notes

itself1EBI-2261609,EBI-2261609

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 290290Putative phosphatase MPN_427
PRO_0000054441

Regions

Region53 – 542Phosphate binding By similarity

Sites

Active site161Nucleophile By similarity
Metal binding161Magnesium By similarity
Metal binding181Magnesium; via carbonyl oxygen By similarity
Metal binding2391Magnesium By similarity
Metal binding2401Magnesium By similarity
Binding site171Phosphate; via amide nitrogen By similarity
Binding site2161Phosphate By similarity
Binding site2421Phosphate By similarity

Sequences

Sequence LengthMass (Da)Tools
P75360 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: FCA0416EDEEE48CA

FASTA29033,216
        10         20         30         40         50         60 
MTKTSKASGL SWFFCDLDGT LLRYQNNQHL IEPTTKRAVA QLVESGANFV VATGRKPSDV 

        70         80         90        100        110        120 
RNIYKELGIE QASPYLIANN GAVVWDLKRN SYLNKQTLSL SDFDLIDHIN QTLNQLNHEY 

       130        140        150        160        170        180 
GCILYGLNDQ VYFYHIHAPD SQAFKQYFAF YEGEFVQNQY LEIDGLKTEY NLVKAIWFFK 

       190        200        210        220        230        240 
EVHQQKAVIA QHFTNQERLV ITSAHSFELV PLNVSKGHAI NLIKQQVKIT DNQIMVLGDS 

       250        260        270        280        290 
YNDLPMFQHG VVKVTNHLAP DNLKQLATRV YELPASLFVG QALNDYFKFD 

« Hide

References

[1]"Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29342 / M129.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U00089 Genomic DNA. Translation: AAB96062.1.
PIRS73740.
RefSeqNP_110115.1. NC_000912.1.

3D structure databases

ProteinModelPortalP75360.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272634.MPN427.

Proteomic databases

PaxDbP75360.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB96062; AAB96062; MPN_427.
GeneID876743.
KEGGmpn:MPN427.
PATRIC20022250. VBIMycPne110_0462.

Phylogenomic databases

eggNOGCOG0561.
KOK07024.
OMAMIEQAGI.
OrthoDBEOG6K13W0.
ProtClustDBCLSK335146.

Enzyme and pathway databases

BioCycMPNE272634:GJ6Z-456-MONOMER.

Family and domain databases

Gene3D3.40.50.1000. 2 hits.
InterProIPR023214. HAD-like_dom.
IPR006379. HAD-SF_hydro_IIB.
IPR000150. Hypothet_cof.
[Graphical view]
PfamPF08282. Hydrolase_3. 1 hit.
[Graphical view]
SUPFAMSSF56784. SSF56784. 1 hit.
TIGRFAMsTIGR00099. Cof-subfamily. 1 hit.
TIGR01484. HAD-SF-IIB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameY427_MYCPN
AccessionPrimary (citable) accession number: P75360
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: April 16, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Mycoplasma pneumoniae

Mycoplasma pneumoniae (strain M129): entries and gene names