ID   PTAS_MYCPN              Reviewed;         320 AA.
AC   P75359;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   27-MAR-2024, entry version 109.
DE   RecName: Full=Phosphate acetyltransferase;
DE            EC=2.3.1.8;
DE   AltName: Full=Phosphotransacetylase;
GN   Name=pta; OrderedLocusNames=MPN_428; ORFNames=MP413;
OS   Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1)
OS   (Mycoplasmoides pneumoniae).
OC   Bacteria; Mycoplasmatota; Mycoplasmoidales; Mycoplasmoidaceae;
OC   Mycoplasmoides.
OX   NCBI_TaxID=272634;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29342 / M129 / Subtype 1;
RX   PubMed=8948633; DOI=10.1093/nar/24.22.4420;
RA   Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.;
RT   "Complete sequence analysis of the genome of the bacterium Mycoplasma
RT   pneumoniae.";
RL   Nucleic Acids Res. 24:4420-4449(1996).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=acetyl-CoA + phosphate = acetyl phosphate + CoA;
CC         Xref=Rhea:RHEA:19521, ChEBI:CHEBI:22191, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:57287, ChEBI:CHEBI:57288; EC=2.3.1.8;
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis;
CC       acetyl-CoA from acetate: step 2/2.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the phosphate acetyltransferase and
CC       butyryltransferase family. {ECO:0000305}.
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DR   EMBL; U00089; AAB96061.1; -; Genomic_DNA.
DR   PIR; S73739; S73739.
DR   RefSeq; NP_110116.1; NC_000912.1.
DR   RefSeq; WP_010874784.1; NC_000912.1.
DR   AlphaFoldDB; P75359; -.
DR   SMR; P75359; -.
DR   IntAct; P75359; 2.
DR   STRING; 272634.MPN_428; -.
DR   EnsemblBacteria; AAB96061; AAB96061; MPN_428.
DR   KEGG; mpn:MPN_428; -.
DR   PATRIC; fig|272634.6.peg.463; -.
DR   HOGENOM; CLU_019723_0_1_14; -.
DR   OrthoDB; 9805787at2; -.
DR   BioCyc; MetaCyc:MONOMER-602; -.
DR   BioCyc; MPNE272634:G1GJ3-692-MONOMER; -.
DR   UniPathway; UPA00340; UER00459.
DR   Proteomes; UP000000808; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008959; F:phosphate acetyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006085; P:acetyl-CoA biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.40.50.10950; -; 1.
DR   Gene3D; 3.40.50.10750; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
DR   InterPro; IPR012147; P_Ac_Bu_trans.
DR   InterPro; IPR004614; P_AcTrfase.
DR   InterPro; IPR042113; P_AcTrfase_dom1.
DR   InterPro; IPR042112; P_AcTrfase_dom2.
DR   InterPro; IPR002505; PTA_PTB.
DR   NCBIfam; TIGR00651; pta; 1.
DR   PANTHER; PTHR43356; PHOSPHATE ACETYLTRANSFERASE; 1.
DR   PANTHER; PTHR43356:SF3; PHOSPHATE ACETYLTRANSFERASE; 1.
DR   Pfam; PF01515; PTA_PTB; 1.
DR   PIRSF; PIRSF000428; P_Ac_trans; 1.
DR   SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
PE   3: Inferred from homology;
KW   Acyltransferase; Cytoplasm; Reference proteome; Transferase.
FT   CHAIN           1..320
FT                   /note="Phosphate acetyltransferase"
FT                   /id="PRO_0000179134"
SQ   SEQUENCE   320 AA;  35219 MW;  DD1E674A6E4E898F CRC64;
     MSVIDLLKQR VQSAGKKPVI IFPEGWSPTV MEAVNQLQQA GILTPPVIFR TRSEVPAGFN
     TAIKHYVIEE MDLTKYANFV YEKRKHKGME MREAQKFVRD ASSLAATLVA LNEVDGEVCG
     KEYATKDTLR PALQLLGTGN FVSSVFIMEK NEERLYFTDC AFAVYPSPQE LAVVAENTFK
     FAQSMGEPEL KMVFLSYSTL GSGKGEAVDK VVSATQIFLE KHPELKANVC GELQFDSAFV
     EKVRKQKAPN LTWNGSANIY VFPNLDAGNI GYKIAQRLGG YEAIGPIVLG LARPFNDLSR
     GASVSDVFNV GIITAAQTLK
//