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P75305 (AZOR_MYCPN) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Interactions·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
FMN-dependent NADH-azoreductase

EC=1.7.-.-
Alternative name(s):
Azo-dye reductase
FMN-dependent NADH-azo compound oxidoreductase
Gene names
Name:azoR
Ordered Locus Names:MPN_479
ORF Names:MP362
OrganismMycoplasma pneumoniae (strain ATCC 29342 / M129) [Reference proteome] [HAMAP]
Taxonomic identifier272634 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length197 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity By similarity. HAMAP-Rule MF_01216

Cofactor

Binds 1 FMN per subunit By similarity. HAMAP-Rule MF_01216

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_01216

Sequence similarities

Belongs to the azoreductase type 1 family.

Binary interactions

With

Entry

#Exp.

IntAct

Notes

MPN_040P750741EBI-2260147,EBI-2260151

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 197197FMN-dependent NADH-azoreductase HAMAP-Rule MF_01216
PRO_0000166345

Sequences

Sequence LengthMass (Da)Tools
P75305 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: B566B394F7936D31

FASTA19721,550
        10         20         30         40         50         60 
MKKVIIIDAS VSPSGSYTHL LLERFLATFQ AKNKDVELST WNLNELPVGQ ISYNTQNAGT 

        70         80         90        100        110        120 
FFSVENSDKY IDALKAAHGV IILAPMTNFN YPATLKNFID HVFVANKTFK DKYVTKGASS 

       130        140        150        160        170        180 
GMLGNLKVVV LGSQGAPLGW YPWGDHVNSL RGLFGFAGVA SFASVIIDGT KLLYKDKSKS 

       190 
EVVDMFAKQV DAIANEF 

« Hide

References

[1]"Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29342 / M129.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U00089 Genomic DNA. Translation: AAB96010.1.
PIRS73688.
RefSeqNP_110167.1. NC_000912.1.

3D structure databases

ProteinModelPortalP75305.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActP75305. 1 interaction.
STRING272634.MPN479.

Proteomic databases

PaxDbP75305.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB96010; AAB96010; MPN_479.
GeneID876744.
KEGGmpn:MPN479.
PATRIC20022382. VBIMycPne110_0518.

Phylogenomic databases

eggNOGCOG1182.
KOK01118.
OMAATTKNFF.
OrthoDBEOG6QRW9T.

Enzyme and pathway databases

BioCycMPNE272634:GJ6Z-520-MONOMER.

Family and domain databases

Gene3D3.40.50.360. 1 hit.
HAMAPMF_01216. Azoreductase_type1.
InterProIPR003680. Flavodoxin_fold.
IPR029039. Flavoprotein-like.
IPR023048. NADH-azoreductase_FMN-depdnt.
[Graphical view]
PANTHERPTHR10204:SF4. PTHR10204:SF4. 1 hit.
PfamPF02525. Flavodoxin_2. 1 hit.
[Graphical view]
SUPFAMSSF52218. SSF52218. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAZOR_MYCPN
AccessionPrimary (citable) accession number: P75305
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: June 11, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Mycoplasma pneumoniae

Mycoplasma pneumoniae (strain M129): entries and gene names