Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P75298 (CSD_MYCPN) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable cysteine desulfurase

EC=2.8.1.7
Gene names
Name:csd
Ordered Locus Names:MPN_487
ORF Names:MP355
OrganismMycoplasma pneumoniae (strain ATCC 29342 / M129) [Reference proteome] [HAMAP]
Taxonomic identifier272634 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length408 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine By similarity.

Catalytic activity

L-cysteine + acceptor = L-alanine + S-sulfanyl-acceptor.

Cofactor

Pyridoxal phosphate By similarity.

Sequence similarities

Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

Ontologies

Keywords
   LigandPyridoxal phosphate
   Molecular functionTransferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functioncysteine desulfurase activity

Inferred from electronic annotation. Source: UniProtKB-EC

pyridoxal phosphate binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 408408Probable cysteine desulfurase
PRO_0000150300

Amino acid modifications

Modified residue2251N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
P75298 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 0D0AF371A2AFE26F

FASTA40846,483
        10         20         30         40         50         60 
MTKTKFNPYQ FRKQFKWFKN NPQWVNFDNA ATSIALDTVS QACKEYYELF SVNPHNKTPD 

        70         80         90        100        110        120 
LNNQIIAIIA ETRQLVADWF NVTALEIIFT SSATESINLF AHGLKPWIKP GDEIVLKGDE 

       130        140        150        160        170        180 
HSANVLPWVA LAKQTKARLV WVEKQANQSL EDTFKSLINP KTKVVAITAT SNLFGNSIDF 

       190        200        210        220        230        240 
AQIADYLKQV NPKAFVAVDA VQTVQHKQID IAKTQIDFLA FSTHKFYGPT GLGVAYIKKS 

       250        260        270        280        290        300 
LQPQLQPLKL GGDIFTQIDP DNTIHFKSTP LKFEAGTPNI MAIYALNKLL RFFKQKFNFA 

       310        320        330        340        350        360 
QMMAYGHQLK QQAYELLNSN PQIVLANHDQ DVPIFSFKHR QLATIDLATF LNINKIMVRQ 

       370        380        390        400 
GSICVGRYRN KDYFVRVSLM HYNTVKELQY LAKLLATDTK TIIKNVIK 

« Hide

References

[1]"Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29342 / M129.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U00089 Genomic DNA. Translation: AAB96003.1.
PIRS73681.
RefSeqNP_110175.1. NC_000912.1.

3D structure databases

ProteinModelPortalP75298.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActP75298. 2 interactions.
STRING272634.MPN487.

Proteomic databases

PaxDbP75298.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB96003; AAB96003; MPN_487.
GeneID877233.
KEGGmpn:MPN487.
PATRIC20022398. VBIMycPne110_0526.

Phylogenomic databases

eggNOGCOG0520.
KOK11717.
OMAHQEINGH.
OrthoDBEOG68DD0M.
ProtClustDBCLSK335288.

Enzyme and pathway databases

BioCycMPNE272634:GJ6Z-528-MONOMER.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProIPR000192. Aminotrans_V/Cys_dSase.
IPR020578. Aminotrans_V_PyrdxlP_BS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamPF00266. Aminotran_5. 1 hit.
[Graphical view]
SUPFAMSSF53383. SSF53383. 1 hit.
PROSITEPS00595. AA_TRANSFER_CLASS_5. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCSD_MYCPN
AccessionPrimary (citable) accession number: P75298
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: November 13, 2013
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Mycoplasma pneumoniae

Mycoplasma pneumoniae (strain M129): entries and gene names