P75294 (ULAE_MYCPN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable L-ribulose-5-phosphate 3-epimerase UlaE
EC=5.1.3.22

Alternative name(s):
L-ascorbate utilization protein E
L-xylulose-5-phosphate 3-epimerase

Gene names

Name:	ulaE
Synonyms:	sgaU
Ordered Locus Names:	MPN_492
ORF Names:	MP350

Organism

Mycoplasma pneumoniae (strain ATCC 29342 / M129) [Reference proteome] [HAMAP]

Taxonomic identifier

272634 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Tenericutes › Mollicutes › Mycoplasmatales › Mycoplasmataceae › Mycoplasma › Mycoplasma pneumoniae

Protein attributes

Sequence length	305 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the isomerization of L-xylulose-5-phosphate to L-ribulose-5-phosphate. Is involved in the anaerobic L-ascorbate utilization By similarity.
Catalytic activity	L-ribulose 5-phosphate = L-xylulose 5-phosphate.
Pathway	Cofactor degradation; L-ascorbate degradation; D-xylulose 5-phosphate from L-ascorbate: step 3/4.
Sequence similarities	Belongs to the L-ribulose-5-phosphate 3-epimerase family.

Ontologies

Keywords
Molecular function	Isomerase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	L-ascorbic acid catabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	L-ribulose-5-phosphate 3-epimerase activity Inferred from electronic annotation. Source: EC intramolecular oxidoreductase activity, interconverting aldoses and ketoses Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 305	305	Probable L-ribulose-5-phosphate 3-epimerase UlaE		PRO_0000097717

Sequences

	Sequence		Length	Mass (Da)
	P75294 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: DCDB9D0709CBA51B	FASTA	305	34,888
	10 20 30 40 50 60 MLVIHFKPYN NLKMSFTSTE NKHLLGVYEK AINNKFAWKD KIAIAKQASF DFIELSIDES 70 80 90 100 110 120 DARLQRLDWS DTEINQLHNE LQAQTFCLNS MCLSAHRRFP LGSKNKTTVQ QGLTIFEKAC 130 140 150 160 170 180 VLARKLGIRI IQLAAYDVYY EPHDTETERN FITNMRKVAE LAQKYAVTIA FEVMDTPFAG 190 200 210 220 230 240 TIVRCLNLIK RIGKANILLY PDIGNLSQFS TAVFDEIALG QDKIVGFHFK DTLPKQFKEV 250 260 270 280 290 300 PFGTGTAQFE AALKAIHQYV PTVPILIEMW SKNDPAESTV QNVAQLKQAK QFYEQQWDLA LKRVK

References

[1]

"Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae." Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R. Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29342 / M129.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U00089 Genomic DNA. Translation: AAB95998.1.
PIR	S73676.
RefSeq	NP_110180.1. NC_000912.1.
3D structure databases
ProteinModelPortal	P75294.
ModBase	Search...
Protein-protein interaction databases
IntAct	P75294. 3 interactions.
STRING	272634.MPN492.
Proteomic databases
PaxDb	P75294.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAB95998; AAB95998; MPN_492.
GeneID	877214.
KEGG	mpn:MPN492.
PATRIC	20022410. VBIMycPne110_0532.
Phylogenomic databases
eggNOG	COG3623.
KO	K03079.
OMA	AFLIEMW.
ProtClustDB	PRK13209.
Enzyme and pathway databases
BioCyc	MPNE272634:GJ6Z-533-MONOMER.
UniPathway	UPA00263; UER00379.
Family and domain databases
Gene3D	3.20.20.150. 1 hit.
InterPro	IPR004560. Hxl6Piso_put. IPR013022. Xyl_isomerase-like_TIM-brl. [Graphical view]
Pfam	PF01261. AP_endonuc_2. 1 hit. [Graphical view]
SUPFAM	SSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
TIGRFAMs	TIGR00542. hxl6Piso_put. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ULAE_MYCPN

Accession

Primary (citable) accession number: P75294

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	February 1, 1997
Last modified:	May 1, 2013
This is version 78 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program