Reviewed, UniProtKB/Swiss-Prot P75289 (ULAF_MYCPN)

Names and origin

Protein names

Recommended name:
    Probable L-ribulose-5-phosphate 4-epimerase ulaF
    EC=5.1.3.4
Alternative name(s):
    Phosphoribulose isomerase
    L-ascorbate utilization protein F

Gene names

Name:	ulaF
Synonyms:	sgaE
Ordered Locus Names:	MPN_498
ORF Names:	MP345

Organism

Mycoplasma pneumoniae [Complete proteome] [HAMAP]

Taxonomic identifier

2104 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma

Protein attributes

Sequence length	242 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate. Is involved in the anaerobic L-ascorbate utilization By similarity.
Catalytic activity	L-ribulose 5-phosphate = D-xylulose 5-phosphate.
Cofactor	Binds 1 zinc ion per subunit Potential.
Pathway	Cofactor degradation; L-ascorbate degradation; D-xylulose 5-phosphate from L-ascorbate: step 4/4.
Sequence similarities	Belongs to the aldolase class II family. AraD/fucA subfamily.

Ontologies

Keywords
Ligand	Metal-binding Zinc
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	L-ribulose-phosphate 4-epimerase activity Inferred from electronic annotation. Source: EC zinc ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 242	242	Probable L-ribulose-5-phosphate 4-epimerase ulaF		PRO_0000162922
Sites
	Metal binding	80	1	Zinc By similarity
	Metal binding	99	1	Zinc By similarity
	Metal binding	101	1	Zinc By similarity
	Metal binding	175	1	Zinc By similarity

Sequences

	Sequence		Length	Mass (Da)
	P75289-1 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 3F326B0F364CBB8B	FASTA	242	27,092
	10 20 30 40 50 60 MDQKMINDLK EQVFQTNLLL PKYGLVIHTW GNVSMIAPNR QFFVIKPSGV SYDKMRAQDM 70 80 90 100 110 120 VVVDLDNNVL DTNGLKPSSD TPTHALMYKH CPDIKAIVHT HSTFATSFAQ ADKPIPCLGT 130 140 150 160 170 180 THADNFFGPI PCTRALSDSE INGAYEHNTG LVILEHLKNN QVDVNACAAI LVKEHGSFVW 190 200 210 220 230 240 SNKNGKDAVD RALTLEQVAQ MALYTQMINP HMKEANPALQ QKHYNRKHGK DAYYGQDTKQ ED

References

[1]

"Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae." Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R. Nucleic Acids Res. 24:4420-4449(1996) [PubMed: 8948633] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29342 / M129.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U00089 Genomic DNA. Translation: AAB95992.1.
PIR	S73671.
RefSeq	NP_110186.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	877253.
GenomeReviews	Gene locus MPN_498 in contig U00089_GR.
KEGG	mpn:MPN498.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	P75289.
OMA	DSEINGA
Enzyme and pathway databases
BioCyc	MPNE272634:MPN498-MON.
BRENDA	5.1.3.4. 39500.
Family and domain databases
InterPro	IPR001303. Aldolase_II/adducin_N. [Graphical view]
Gene3D	G3DSA:3.40.225.10. Aldolase_II/adducin_N. 1 hit.
Pfam	PF00596. Aldolase_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ULAF_MYCPN

Accession

Primary (citable) accession number: P75289

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	February 1, 1997
Last modified:	November 24, 2009
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)