P75263 (Y135_MYCPN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable ABC transporter permease protein MG188 homolog

Gene names

Ordered Locus Names:	MPN_135
ORF Names:	E07_orf329, MP019

Organism

Mycoplasma pneumoniae (strain ATCC 29342 / M129) [Reference proteome] [HAMAP]

Taxonomic identifier

272634 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Tenericutes › Mollicutes › Mycoplasmatales › Mycoplasmataceae › Mycoplasma › Mycoplasma pneumoniae

Protein attributes

Sequence length	329 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane.
Subcellular location	Cell membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily. Contains 1 ABC transmembrane type-1 domain.

Ontologies

Keywords
Biological process	Transport
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	transporter activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 329	329	Probable ABC transporter permease protein MG188 homolog		PRO_0000060286
Regions
	Transmembrane	30 – 50	21	Helical; Potential
	Transmembrane	96 – 116	21	Helical; Potential
	Transmembrane	128 – 148	21	Helical; Potential
	Transmembrane	176 – 196	21	Helical; Potential
	Transmembrane	234 – 254	21	Helical; Potential
	Transmembrane	283 – 303	21	Helical; Potential
	Domain	88 – 303	216	ABC transmembrane type-1

Sequences

	Sequence		Length	Mass (Da)
	P75263 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 7DE0D96DDB01C89B	FASTA	329	37,488
	10 20 30 40 50 60 MFKWLLKHRS KPTPLELGIF DQKVSFWKPF LLFCPALLTT FLFTLVPFFL TLQKGFSHNE 70 80 90 100 110 120 DIYRVDSQQF GFQTFANLFS ESNFILGLRN SFLYSIISLP LTIVLAIIIS SAIVFVYRKL 130 140 150 160 170 180 ARGFWQTVFF LPYVTSGVAV SIAFIYILDS SSGILNNIFH VNIKWLDSGE RDTFNALWGI 190 200 210 220 230 240 LIFGIWKNMA FNVLVISTAM LSVDPTLYKV ANLDGAKPIR QFFKITLPSI RPTLIFLLTL 250 260 270 280 290 300 LILGGMQVFP ISLFNGNDSE AVTNGGSTIL LYIFQKIRDQ NNNFAGAATL VLFILGVCYG 310 320 LVLRNGFRLI EWAQWKIKRH YVQTKLNLV

References

[1]

"Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae." Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R. Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29342 / M129.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U00089 Genomic DNA. Translation: AAB95667.1.
PIR	S73345.
RefSeq	NP_109823.1. NC_000912.1.
3D structure databases
ProteinModelPortal	P75263.
ModBase	Search...
Protein-protein interaction databases
IntAct	P75263. 1 interaction.
STRING	272634.MPN135.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAB95667; AAB95667; MPN_135.
GeneID	877306.
KEGG	mpn:MPN135.
PATRIC	20021585. VBIMycPne110_0149.
Phylogenomic databases
eggNOG	COG1175.
KO	K02025.
OMA	DTFNALW.
ProtClustDB	CLSK782791.
Enzyme and pathway databases
BioCyc	MPNE272634:GJ6Z-142-MONOMER.
Family and domain databases
InterPro	IPR000515. BPD_transp. [Graphical view]
Pfam	PF00528. BPD_transp_1. 1 hit. [Graphical view]
PROSITE	PS50928. ABC_TM1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y135_MYCPN

Accession

Primary (citable) accession number: P75263

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	February 1, 1997
Last modified:	May 1, 2013
This is version 75 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program