ID   ADH_MYCPN               Reviewed;         351 AA.
AC   P75214;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   16-JUN-2009, entry version 53.
DE   RecName: Full=Probable NADP-dependent alcohol dehydrogenase;
DE            EC=1.1.1.2;
GN   Name=adh; OrderedLocusNames=MPN_564; ORFNames=MP278;
OS   Mycoplasma pneumoniae.
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=2104;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29342 / M129;
RX   MEDLINE=97105885; PubMed=8948633; DOI=10.1093/nar/24.22.4420;
RA   Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C.,
RA   Herrmann R.;
RT   "Complete sequence analysis of the genome of the bacterium Mycoplasma
RT   pneumoniae.";
RL   Nucleic Acids Res. 24:4420-4449(1996).
CC   -!- CATALYTIC ACTIVITY: An alcohol + NADP(+) = an aldehyde + NADPH.
CC   -!- COFACTOR: Binds 1 zinc ion per subunit (By similarity).
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; U00089; AAB95926.1; -; Genomic_DNA.
DR   PIR; S73604; S73604.
DR   RefSeq; NP_110253.1; -.
DR   HSSP; P14941; 1YKF.
DR   GeneID; 876853; -.
DR   GenomeReviews; U00089_GR; MPN_564.
DR   KEGG; mpn:MPN564; -.
DR   HOGENOM; P75214; -.
DR   OMA; P75214; HTVFEGA.
DR   BioCyc; MPNE272634:MPN564-MON; -.
DR   BRENDA; 1.1.1.2; 39500.
DR   GO; GO:0008106; F:alcohol dehydrogenase (NADP+) activity; IEA:EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR013154; ADH_GroES-like.
DR   InterPro; IPR002085; ADH_SF_Zn.
DR   InterPro; IPR013149; ADH_Zn-bd.
DR   InterPro; IPR002328; ADH_Zn_CS.
DR   PANTHER; PTHR11695; ADH_Sf_Zn; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   PROSITE; PS00059; ADH_ZINC; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Metal-binding; NADP; Oxidoreductase; Zinc.
FT   CHAIN         1    351       Probable NADP-dependent alcohol
FT                                dehydrogenase.
FT                                /FTId=PRO_0000160746.
FT   METAL        37     37       Zinc; catalytic (By similarity).
FT   METAL        59     59       Zinc; catalytic (By similarity).
FT   METAL        60     60       Zinc; catalytic (By similarity).
FT   METAL       150    150       Zinc; catalytic (By similarity).
SQ   SEQUENCE   351 AA;  37812 MW;  3153B93BFFE64D2C CRC64;
     MKAYAMLKIG ATGWIEKPRP VCGPNDAIIR PLAVAPCTSD VHTVWEGGIG ERHNMVLGHE
     GCGVVDEVGS EVKSFKVGDR VLVAAITPEW NSVNAQAGYP MHSGGMLGGW KFSNVKDGMF
     AEYFHVNDAE GNLALMPEGM DLADACMLSD MIPTGFHANE LADIQYGVAL SFFCAGPVGL
     MAIAGAALKG AGRIIVVDSR PDIVEIAKAY GATDYIDFKK VSVVDEILKW TNNEGVEKVL
     ISGGGSTILE TAIKVLRPGG KIGNVNYFGA GEFLTIPRVE WGVGMAHKAI HGGLMLGGRL
     RLEKLARLIM TKKLDPSKMI THRFKGFEHI EEALFLMKDK PKDLIKSVVI F
//