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Protein

10 kDa chaperonin

Gene

groS

Organism
Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.By similarity

GO - Biological processi

  1. protein folding Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Enzyme and pathway databases

BioCyciMPNE272634:GJ6Z-620-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
10 kDa chaperonin
Alternative name(s):
GroES protein
Protein Cpn10
Gene namesi
Name:groS
Synonyms:groES, mopB
Ordered Locus Names:MPN_574
ORF Names:MP268
OrganismiMycoplasma pneumoniae (strain ATCC 29342 / M129)
Taxonomic identifieri272634 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000808: Chromosome

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 11611610 kDa chaperoninPRO_0000174790Add
BLAST

Proteomic databases

PaxDbiP75205.

Interactioni

Subunit structurei

Heptamer of 7 subunits arranged in a ring.By similarity

Protein-protein interaction databases

IntActiP75205. 4 interactions.
STRINGi272634.MPN574.

Structurei

3D structure databases

ProteinModelPortaliP75205.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GroES chaperonin family.Curated

Phylogenomic databases

eggNOGiCOG0234.
KOiK04078.
OMAiFKEYSGI.
OrthoDBiEOG6GFGSD.

Family and domain databases

Gene3Di2.30.33.40. 1 hit.
HAMAPiMF_00580. CH10.
InterProiIPR020818. Chaperonin_Cpn10.
IPR011032. GroES-like.
[Graphical view]
PfamiPF00166. Cpn10. 1 hit.
[Graphical view]
PRINTSiPR00297. CHAPERONIN10.
SMARTiSM00883. Cpn10. 1 hit.
[Graphical view]
SUPFAMiSSF50129. SSF50129. 1 hit.

Sequencei

Sequence statusi: Complete.

P75205-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKITPIHDNI LVSLVESNKE EVSQKGIITA LANPDKNESA HKGTVVALGA
60 70 80 90 100
GPAYGKSEKP KYAFGIGDTI YFKEYSGISF EEEGTKYKII SLEDVLAFEK
110
HGNTKTTTVK KGAKKK
Length:116
Mass (Da):12,618
Last modified:February 1, 1997 - v1
Checksum:iDBC4C83372334E52
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00089 Genomic DNA. Translation: AAB95916.1.
PIRiS73594.
RefSeqiNP_110263.1. NC_000912.1.

Genome annotation databases

EnsemblBacteriaiAAB95916; AAB95916; MPN_574.
GeneIDi876761.
KEGGimpn:MPN574.
PATRICi20022627. VBIMycPne110_0636.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00089 Genomic DNA. Translation: AAB95916.1.
PIRiS73594.
RefSeqiNP_110263.1. NC_000912.1.

3D structure databases

ProteinModelPortaliP75205.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP75205. 4 interactions.
STRINGi272634.MPN574.

Proteomic databases

PaxDbiP75205.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB95916; AAB95916; MPN_574.
GeneIDi876761.
KEGGimpn:MPN574.
PATRICi20022627. VBIMycPne110_0636.

Phylogenomic databases

eggNOGiCOG0234.
KOiK04078.
OMAiFKEYSGI.
OrthoDBiEOG6GFGSD.

Enzyme and pathway databases

BioCyciMPNE272634:GJ6Z-620-MONOMER.

Family and domain databases

Gene3Di2.30.33.40. 1 hit.
HAMAPiMF_00580. CH10.
InterProiIPR020818. Chaperonin_Cpn10.
IPR011032. GroES-like.
[Graphical view]
PfamiPF00166. Cpn10. 1 hit.
[Graphical view]
PRINTSiPR00297. CHAPERONIN10.
SMARTiSM00883. Cpn10. 1 hit.
[Graphical view]
SUPFAMiSSF50129. SSF50129. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
    Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
    Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29342 / M129.

Entry informationi

Entry nameiCH10_MYCPN
AccessioniPrimary (citable) accession number: P75205
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: January 7, 2015
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Mycoplasma pneumoniae
    Mycoplasma pneumoniae (strain M129): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.