Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative type-1 restriction enzyme specificity protein MPN_615

Gene

MPN_615

Organism
Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity (By similarity).By similarity

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW

GO - Biological processi

  1. DNA restriction-modification system Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Restriction system

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciMPNE272634:GJ6Z-661-MONOMER.

Protein family/group databases

REBASEi6707. S.MpnORF615P.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative type-1 restriction enzyme specificity protein MPN_615
Alternative name(s):
S.MpnORFHP
Type I restriction enzyme specificity protein MPN_615
Short name:
S protein
Gene namesi
Ordered Locus Names:MPN_615
ORF Names:C12_orf249, MP227
OrganismiMycoplasma pneumoniae (strain ATCC 29342 / M129)
Taxonomic identifieri272634 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000808 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 249249Putative type-1 restriction enzyme specificity protein MPN_615PRO_0000198052Add
BLAST

Interactioni

Subunit structurei

The type I restriction/modification system is composed of three polypeptides R, M and S.By similarity

Protein-protein interaction databases

IntActiP75180. 2 interactions.
STRINGi272634.MPN615.

Structurei

3D structure databases

ProteinModelPortaliP75180.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domaini

Contains two DNA recognition domains, each specifying recognition of one of the two defined components of the target sequence.By similarity

Sequence similaritiesi

Phylogenomic databases

OMAiSARPMIS.
OrthoDBiEOG6PKF94.

Family and domain databases

InterProiIPR000055. Restrct_endonuc_typeI_HsdS.
[Graphical view]
PfamiPF01420. Methylase_S. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P75180-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQGILAEIEL DFPPLQIQEK IATILDTFTE LSAELRERKK QYAFYRDYLL
60 70 80 90 100
NQENIRKIYG ANIPFETFQV KDICEIRRGR AITKAYIRNN PGENPVYSAA
110 120 130 140 150
TTNDGELGRI KDCDFDGEYI TWTTNGYAGV VFYRNGKFNA SQDCGVLKVK
160 170 180 190 200
NKKICTKFLS FLLKIEAPKF VHNLASRPKL SQKVMAEIEL SFPPLEIQEK
210 220 230 240
IADILFAFEK LCNDLVEGIP AEIEMRKKQL DYYYHLIFSK IAHFSKQLA
Length:249
Mass (Da):28,758
Last modified:February 1, 1997 - v1
Checksum:i14AC1D1350DB5855
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00089 Genomic DNA. Translation: AAB95875.1.
PIRiS73553.

Genome annotation databases

EnsemblBacteriaiAAB95875; AAB95875; MPN_615.
PATRICi20022713. VBIMycPne110_0679.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00089 Genomic DNA. Translation: AAB95875.1.
PIRiS73553.

3D structure databases

ProteinModelPortaliP75180.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP75180. 2 interactions.
STRINGi272634.MPN615.

Protein family/group databases

REBASEi6707. S.MpnORF615P.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB95875; AAB95875; MPN_615.
PATRICi20022713. VBIMycPne110_0679.

Phylogenomic databases

OMAiSARPMIS.
OrthoDBiEOG6PKF94.

Enzyme and pathway databases

BioCyciMPNE272634:GJ6Z-661-MONOMER.

Family and domain databases

InterProiIPR000055. Restrct_endonuc_typeI_HsdS.
[Graphical view]
PfamiPF01420. Methylase_S. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
    Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
    Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29342 / M129.

Entry informationi

Entry nameiT1SH_MYCPN
AccessioniPrimary (citable) accession number: P75180
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: February 1, 1997
Last modified: January 7, 2015
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Mycoplasma pneumoniae
    Mycoplasma pneumoniae (strain M129): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.