Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative phosphatidate cytidylyltransferase

Gene

cdsA

Organism
Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

CTP + phosphatidate = diphosphate + CDP-diacylglycerol.

Pathwayi: CDP-diacylglycerol biosynthesis

This protein is involved in step 3 of the subpathway that synthesizes CDP-diacylglycerol from sn-glycerol 3-phosphate.
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase (plsC)
  3. Putative phosphatidate cytidylyltransferase (cdsA)
This subpathway is part of the pathway CDP-diacylglycerol biosynthesis, which is itself part of Phospholipid metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes CDP-diacylglycerol from sn-glycerol 3-phosphate, the pathway CDP-diacylglycerol biosynthesis and in Phospholipid metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferase, Transferase
Biological processLipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

Enzyme and pathway databases

BioCyciMPNE272634:G1GJ3-1020-MONOMER
UniPathwayiUPA00557; UER00614

Names & Taxonomyi

Protein namesi
Recommended name:
Putative phosphatidate cytidylyltransferase (EC:2.7.7.41)
Alternative name(s):
CDP-DAG synthase
CDP-DG synthase
CDP-diacylglycerol synthase
Short name:
CDS
CDP-diglyceride pyrophosphorylase
CDP-diglyceride synthase
CTP:phosphatidate cytidylyltransferase
Gene namesi
Name:cdsA
Ordered Locus Names:MPN_637
ORF Names:MP205
OrganismiMycoplasma pneumoniae (strain ATCC 29342 / M129)
Taxonomic identifieri272634 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
Proteomesi
  • UP000000808 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei13 – 33HelicalSequence analysisAdd BLAST21
Transmembranei78 – 98HelicalSequence analysisAdd BLAST21
Transmembranei115 – 135HelicalSequence analysisAdd BLAST21
Transmembranei144 – 164HelicalSequence analysisAdd BLAST21
Transmembranei177 – 197HelicalSequence analysisAdd BLAST21
Transmembranei201 – 221HelicalSequence analysisAdd BLAST21
Transmembranei242 – 262HelicalSequence analysisAdd BLAST21
Transmembranei306 – 326HelicalSequence analysisAdd BLAST21
Transmembranei358 – 378HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000907401 – 395Putative phosphatidate cytidylyltransferaseAdd BLAST395

Proteomic databases

PRIDEiP75160

Family & Domainsi

Sequence similaritiesi

Belongs to the CDS family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

KOiK00981
OMAiHAPDNIS

Family and domain databases

InterProiView protein in InterPro
IPR000374 PC_trans
PROSITEiView protein in PROSITE
PS01315 CDS, 1 hit

Sequencei

Sequence statusi: Complete.

P75160-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLKDNSFAK KRSTVFVVLL IVFCFFLMFS AFADGFNFWS PWSTDFNSRV
60 70 80 90 100
IHIKSDGNIE TTSIVSHELH PDFKAVRFAF GLVIVLFISV IAVLMNWELS
110 120 130 140 150
NSIFKNYEKL NLSLSLLSGI MVSGGMIPTF FVIYFREWNA TVNWIWTASF
160 170 180 190 200
AGMIVFLWAV YMISTSFIKI RPSLQVIYSL GAVICFIACI GTIYFSVIRG
210 220 230 240 250
WTTIFLLIAI GVCTDTFAYL FGKRFGKNPL IKISPSKTWE GAFFGVTGTV
260 270 280 290 300
LTISIICVLY SIPNYVRQPS IKDASKTALQ TPQNYDVHNL ITNVFLISFI
310 320 330 340 350
SGGSTFYIYW WVSTLALIFT ASIFAIGGDL FFSYIKRLTK IKDFSKLLGK
360 370 380 390
HGGILDRFDS SSFLISFFFI YHVIAGISSN QRLLMEPNTY FSAVS
Length:395
Mass (Da):44,644
Last modified:February 1, 1997 - v1
Checksum:i4AB163423C2E9EFB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00089 Genomic DNA Translation: AAB95853.1
PIRiS73531
RefSeqiNP_110326.1, NC_000912.1
WP_010874994.1, NC_000912.1

Genome annotation databases

EnsemblBacteriaiAAB95853; AAB95853; MPN_637
GeneIDi876996
KEGGimpn:MPN637
PATRICifig|272634.6.peg.700

Similar proteinsi

Entry informationi

Entry nameiCDSA_MYCPN
AccessioniPrimary (citable) accession number: P75160
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: May 23, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Mycoplasma pneumoniae
    Mycoplasma pneumoniae (strain M129): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health