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P75160 (CDSA_MYCPN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Putative phosphatidate cytidylyltransferase

EC=2.7.7.41
Alternative name(s):
CDP-DAG synthase
CDP-DG synthase
CDP-diacylglycerol synthase
Short name=CDS
CDP-diglyceride pyrophosphorylase
CDP-diglyceride synthase
CTP:phosphatidate cytidylyltransferase
Gene names
Name:cdsA
Ordered Locus Names:MPN_637
ORF Names:MP205
OrganismMycoplasma pneumoniae (strain ATCC 29342 / M129) [Reference proteome] [HAMAP]
Taxonomic identifier272634 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length395 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

CTP + phosphatidate = diphosphate + CDP-diacylglycerol.

Pathway

Phospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3.

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the CDS family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 395395Putative phosphatidate cytidylyltransferase
PRO_0000090740

Regions

Transmembrane13 – 3321Helical; Potential
Transmembrane78 – 9821Helical; Potential
Transmembrane115 – 13521Helical; Potential
Transmembrane144 – 16421Helical; Potential
Transmembrane177 – 19721Helical; Potential
Transmembrane201 – 22121Helical; Potential
Transmembrane242 – 26221Helical; Potential
Transmembrane306 – 32621Helical; Potential
Transmembrane358 – 37821Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P75160 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 4AB163423C2E9EFB

FASTA39544,644
        10         20         30         40         50         60 
MDLKDNSFAK KRSTVFVVLL IVFCFFLMFS AFADGFNFWS PWSTDFNSRV IHIKSDGNIE 

        70         80         90        100        110        120 
TTSIVSHELH PDFKAVRFAF GLVIVLFISV IAVLMNWELS NSIFKNYEKL NLSLSLLSGI 

       130        140        150        160        170        180 
MVSGGMIPTF FVIYFREWNA TVNWIWTASF AGMIVFLWAV YMISTSFIKI RPSLQVIYSL 

       190        200        210        220        230        240 
GAVICFIACI GTIYFSVIRG WTTIFLLIAI GVCTDTFAYL FGKRFGKNPL IKISPSKTWE 

       250        260        270        280        290        300 
GAFFGVTGTV LTISIICVLY SIPNYVRQPS IKDASKTALQ TPQNYDVHNL ITNVFLISFI 

       310        320        330        340        350        360 
SGGSTFYIYW WVSTLALIFT ASIFAIGGDL FFSYIKRLTK IKDFSKLLGK HGGILDRFDS 

       370        380        390 
SSFLISFFFI YHVIAGISSN QRLLMEPNTY FSAVS 

« Hide

References

[1]"Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29342 / M129.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U00089 Genomic DNA. Translation: AAB95853.1.
PIRS73531.
RefSeqNP_110326.1. NC_000912.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRING272634.MPN637.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB95853; AAB95853; MPN_637.
GeneID876996.
KEGGmpn:MPN637.
PATRIC20022755. VBIMycPne110_0700.

Phylogenomic databases

eggNOGCOG0575.
OMALMEPNTY.
ProtClustDBCLSK437132.

Enzyme and pathway databases

BioCycMPNE272634:GJ6Z-683-MONOMER.
UniPathwayUPA00557; UER00614.

Family and domain databases

InterProIPR000374. PC_trans.
[Graphical view]
PfamPF01148. CTP_transf_1. 1 hit.
[Graphical view]
PROSITEPS01315. CDS. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCDSA_MYCPN
AccessionPrimary (citable) accession number: P75160
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: May 1, 2013
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Mycoplasma pneumoniae

Mycoplasma pneumoniae (strain M129): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families