P75124 (GALU_MYCPN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
UTP--glucose-1-phosphate uridylyltransferase
EC=2.7.7.9

Alternative name(s):
Alpha-D-glucosyl-1-phosphate uridylyltransferase
UDP-glucose pyrophosphorylase
Short name=UDPGP
Uridine diphosphoglucose pyrophosphorylase

Gene names

Name:	galU
Synonyms:	gtaB
Ordered Locus Names:	MPN_667
ORF Names:	MP175

Organism

Mycoplasma pneumoniae (strain ATCC 29342 / M129) [Reference proteome] [HAMAP]

Taxonomic identifier

272634 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Tenericutes › Mollicutes › Mycoplasmatales › Mycoplasmataceae › Mycoplasma › Mycoplasma pneumoniae

Protein attributes

Sequence length	291 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	May play a role in stationary phase survival By similarity.
Catalytic activity	UTP + alpha-D-glucose 1-phosphate = diphosphate + UDP-glucose.
Sequence similarities	Belongs to the UDPGP type 2 family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	UDP-glucose metabolic process Inferred from electronic annotation. Source: InterPro biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular_function	UTP:glucose-1-phosphate uridylyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 291	291	UTP--glucose-1-phosphate uridylyltransferase		PRO_0000201360

Sequences

	Sequence		Length	Mass (Da)
	P75124 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: B422FF63FD64F1CF	FASTA	291	32,168
	10 20 30 40 50 60 MPKIRKAVIP AAGLGTRLLP ATKAIPKEML PLVNKPTIQY IVEEAVASGI KEILVIVSSK 70 80 90 100 110 120 KEAIIDHFDY DFILENALLQ KHKDQEHQEI KDIANLAHIY FVRQKHQHGL GDAILHAKSF 130 140 150 160 170 180 VGNEDFAVLL GDDVVFGEQP ALAQCIQAYE QTDCQVIGVQ EVPHDQVNKY GIVTPEANWQ 190 200 210 220 230 240 KQALVKILGM VEKPAVNEAK SNLAILSRYI LKPSIFTALK QVPFGVGGEL QLTDGLNYCL 250 260 270 280 290 QQGEPFFAKH FGGTRFDVGT KNGFIKANLY TALKTDAITK DEVLAILKEF A

References

[1]

"Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae." Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R. Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29342 / M129.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U00089 Genomic DNA. Translation: AAB95823.1.
PIR	S73501.
RefSeq	NP_110356.1. NC_000912.1.
3D structure databases
ProteinModelPortal	P75124.
ModBase	Search...
Protein-protein interaction databases
STRING	272634.MPN667.
Proteomic databases
PaxDb	P75124.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAB95823; AAB95823; MPN_667.
GeneID	877017.
KEGG	mpn:MPN667.
PATRIC	20022819. VBIMycPne110_0732.
Phylogenomic databases
eggNOG	COG1210.
KO	K00963.
OMA	IQANIAF.
ProtClustDB	CLSK335352.
Enzyme and pathway databases
BioCyc	MetaCyc:MONOMER-642. MPNE272634:GJ6Z-713-MONOMER.
Family and domain databases
InterPro	IPR005771. GalU_uridylyltTrfase_bac/arc. IPR005835. NTP_transferase. [Graphical view]
Pfam	PF00483. NTP_transferase. 1 hit. [Graphical view]
TIGRFAMs	TIGR01099. galU. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GALU_MYCPN

Accession

Primary (citable) accession number: P75124

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	February 1, 1997
Last modified:	May 1, 2013
This is version 73 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program