Reviewed, UniProtKB/Swiss-Prot P75095 (Y018_MYCPN)

Names and origin

Protein names

Recommended name:
    Putative ABC transporter ATP-binding protein MG014 homolog

Gene names

Ordered Locus Names:	MPN_018
ORF Names:	D12_orf623, MP136

Organism

Mycoplasma pneumoniae [Complete proteome] [HAMAP]

Taxonomic identifier

2104 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma

Protein attributes

Sequence length	623 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Subcellular location	Cell membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the ABC transporter superfamily. Contains 1 ABC transmembrane type-1 domain. Contains 1 ABC transporter domain.

Ontologies

Keywords
Biological process	Transport
Cellular component	Cell membrane Membrane
Domain	Transmembrane
Ligand	ATP-binding Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	transmembrane transport Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity, coupled to transmembrane movement of substances Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 623	623	Putative ABC transporter ATP-binding protein MG014 homolog		PRO_0000093236
Regions
	Transmembrane	27 – 47	21	Potential
	Transmembrane	86 – 106	21	Potential
	Transmembrane	157 – 177	21	Potential
	Transmembrane	180 – 200	21	Potential
	Transmembrane	266 – 286	21	Potential
	Transmembrane	307 – 327	21	Potential
	Domain	16 – 325	310	ABC transmembrane type-1
	Domain	365 – 611	247	ABC transporter
	Nucleotide binding	400 – 407	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	P75095-1 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: AB0D481D8AEF736B	FASTA	623	68,928
	10 20 30 40 50 60 MGLVLKQFNR KIRTALILAP LFTFAQIIID LIIPSFLASA IAVVFSIVTL KQKEASGEGV 70 80 90 100 110 120 AVDFIAESKL SFQSVQEAQI VLATSVILLA LFGLVFGLIS IFCASIVAGN TSYFLRRKIF 130 140 150 160 170 180 RKIMHITAPS HDQYGSSTLL VRLTNDVYLM EIMTFDFLRL IVRAPFLFIG GLAFAIATNS 190 200 210 220 230 240 DMSISLAITF PLTFLVIGIL NKKSTPLFKN NQKSVDQINE RVEEDVSGYK VVQSFNLKDT 250 260 270 280 290 300 ECLKFKAANA RWTKSSTNSL FVNTLNIPFT FFFSSMTIII ALLLVFQLDN SVRVDPLPDN 310 320 330 340 350 360 AAIRPSIFAF FQYNFYIVLG LILTSLTMVN FTRSRVALGR IKDVLNKPEI QQHVVPDQTV 370 380 390 400 410 420 LAPSLEFKNV AFGLGNKENR DFLQDLNFKF EAGKTYGIVG PTGSGKSLIA NIIGGLYEPN 430 440 450 460 470 480 QGEIFVGGQS IKTIDSDYLA KMIGIVFQQN ILFKGTIASN IKIGLETRED WKHEPDSKKD 490 500 510 520 530 540 AAMKRAAAIA CADTFIEKFS DTYDHTVEQL GKNLSGGQKQ RVAIARTVIT KPQILVLDDS 550 560 570 580 590 600 MSALDALTEK KVRENIANEL PGTTKIIISQ NINSIKYAHK IMVIDNGRIA GFDSDAKLMQ 610 620 SCDIYVKMKQ AQKDQGGDFD AVA

References

[1]

"Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae." Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R. Nucleic Acids Res. 24:4420-4449(1996) [PubMed: 8948633] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29342 / M129.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U00089 Genomic DNA. Translation: AAB95784.1.
PIR	S73462.
RefSeq	NP_109706.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	876861.
GenomeReviews	Gene locus MPN_018 in contig U00089_GR.
KEGG	mpn:MPN018.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	P75095.
OMA	IISQNIN
Enzyme and pathway databases
BioCyc	MPNE272634:MPN018-MON.
Family and domain databases
InterPro	IPR011527. ABC_TM_1. IPR001140. ABC_TM_transpt. IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR017940. ABC_transporter_type1. IPR003593. ATPase_AAA+_core. [Graphical view]
Pfam	PF00664. ABC_membrane. 1 hit. PF00005. ABC_tran. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. [Graphical view]
PROSITE	PS50929. ABC_TM1F. 1 hit. PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y018_MYCPN

Accession

Primary (citable) accession number: P75095

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	February 1, 1997
Last modified:	November 24, 2009
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)