P75094 (Y019_MYCPN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative ABC transporter ATP-binding protein MG015 homolog

Gene names

Ordered Locus Names:	MPN_019
ORF Names:	D12_orf634, MP135

Organism

Mycoplasma pneumoniae (strain ATCC 29342 / M129)

Taxonomic identifier

272634 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma

Protein attributes

Sequence length	634 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Subcellular location	Cell membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the ABC transporter superfamily. Contains 1 ABC transmembrane type-1 domain. Contains 1 ABC transporter domain.

Ontologies

Keywords
Biological process	Transport
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Ligand	ATP-binding Nucleotide-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity, coupled to transmembrane movement of substances Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 634	634	Putative ABC transporter ATP-binding protein MG015 homolog		PRO_0000093238
Regions
	Transmembrane	54 – 74	21	Helical; Potential
	Transmembrane	111 – 131	21	Helical; Potential
	Transmembrane	189 – 209	21	Helical; Potential
	Transmembrane	213 – 233	21	Helical; Potential
	Transmembrane	296 – 316	21	Helical; Potential
	Transmembrane	325 – 345	21	Helical; Potential
	Domain	54 – 364	311	ABC transmembrane type-1
	Domain	397 – 631	235	ABC transporter
	Nucleotide binding	430 – 437	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	P75094 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: E10CE07E0EB8D406	FASTA	634	71,147
	10 20 30 40 50 60 MLSSCRAVTS MSRWSKHKKT KEVISMLSHN QKPNSWKILW RLIKSVQGRT SSKVLYVMVC 70 80 90 100 110 120 AIFGILTGVT NSILLAQGLG FIFPTTNTET DGIQSVYLLV FAHNLPVMER LTIVCVTVVV 130 140 150 160 170 180 AYILIFSFNV AQNYLGLKLY QEICALLRWK AYLKIQSMST SFFDTQNNGD LMSRLTNDVY 190 200 210 220 230 240 NINNLYAQVG GQTIQSLFIL MTTATILFVL SPVIALISLT VLIALIALSF LFLKKARAAY 250 260 270 280 290 300 AKVQNNLGDM SGYIEEVLSN HKVVHVLKLQ EVMIDNFDKY NRPMVNPTIK ANTYAVFIYS 310 320 330 340 350 360 WFGFISNITY LASISIATAF SVNNIPSFGV SAINYSFMLS YIAALRQTAL PLNQIFSLWN 370 380 390 400 410 420 LIQLGIVSGE RVFKILDLES PQKQATITKL PNIKGNIRFE KVVFGYSADK PILTGIDFSV 430 440 450 460 470 480 KHGDIVAIVG PTGAGKSTII NLLMKFYKPF AGKIYMDNFE ISEVSETAWR EKISIVLQDP 490 500 510 520 530 540 FLFSGTIKEN IRMGRQDATD EEIIEACKVA NAHDFIMRLP QGYNTFISNK TDYLSVGERQ 550 560 570 580 590 600 LLTIARAVIR NAPVLLLDEA TSSIDVHSEK LIQQSIGRLM KDKTSFIISH RLSIIRNATL 610 620 630 IIVINDGKVL EMGNHEQLMR QNGFYARLKR SAVK

References

[1]

"Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae." Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R. Nucleic Acids Res. 24:4420-4449(1996) [PubMed: 8948633] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29342 / M129.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U00089 Genomic DNA. Translation: AAB95783.1.
PIR	S73461.
RefSeq	NP_109707.1. NC_000912.1.
3D structure databases
ProteinModelPortal	P75094.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	877382.
GenomeReviews	Gene locus MPN_019 in contig U00089_GR.
KEGG	mpn:MPN019.
PATRIC	20021313. VBIMycPne110_0018.
Phylogenomic databases
HOGENOM	HBG758042.
OMA	WREKISI.
PhylomeDB	P75094.
ProtClustDB	CLSK542098.
Enzyme and pathway databases
BioCyc	MPNE272634:MPN019-MONOMER.
Family and domain databases
InterPro	IPR003439. ABC_transporter-like. IPR017871. ABC_transporter_CS. IPR017940. ABC_transporter_type1. IPR001140. ABC_transptr_TM_dom. IPR011527. ABC_transptrTM_dom_typ1. IPR003593. ATPase_AAA+_core. [Graphical view]
KO	K06147.
Pfam	PF00664. ABC_membrane. 1 hit. PF00005. ABC_tran. 1 hit. [Graphical view]
SMART	SM00382. AAA. 1 hit. [Graphical view]
SUPFAM	SSF90123. ABC_TM_1. 1 hit.
PROSITE	PS50929. ABC_TM1F. 1 hit. PS00211. ABC_TRANSPORTER_1. 1 hit. PS50893. ABC_TRANSPORTER_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y019_MYCPN

Accession

Primary (citable) accession number: P75094

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	February 1, 1997
Last modified:	January 25, 2012
This is version 78 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program