Reviewed, UniProtKB/Swiss-Prot P75093 (Y020_MYCPN)

Names and origin

Protein names

Recommended name:
    Uncharacterized ATP-dependent helicase MPN_020
    EC=3.6.1.-

Gene names

Ordered Locus Names:	MPN_020
ORF Names:	D12_orf1030, MP134

Organism

Mycoplasma pneumoniae [Complete proteome] [HAMAP]

Taxonomic identifier

2104 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma

Protein attributes

Sequence length	1030 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Sequence similarities

Belongs to the SNF2/RAD54 helicase family. Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain. Contains 1 SWIM-type zinc finger.

Ontologies

Keywords
Domain	Zinc-finger
Ligand	ATP-binding Metal-binding Nucleotide-binding Zinc
Molecular function	Helicase Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA binding Inferred from electronic annotation. Source: InterPro helicase activity Inferred from electronic annotation. Source: UniProtKB-KW zinc ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1030	1030	Uncharacterized ATP-dependent helicase MPN_020		PRO_0000074381
Regions
	Domain	590 – 751	162	Helicase ATP-binding
	Domain	867 – 1021	155	Helicase C-terminal
	Zinc finger	51 – 86	36	SWIM-type
	Nucleotide binding	603 – 610	8	ATP Potential
	Motif	702 – 705	4	DEAQ box

Sequences

	Sequence		Length	Mass (Da)
	P75093-1 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 7272E2B162AF1737	FASTA	1,030	119,602
	10 20 30 40 50 60 MTIAEIRKFA QTTQKFVEAE NLFEHGNVVL PKKYLNKARG MAEVLYNSQV IKVSFTAKDG 70 80 90 100 110 120 ELTCKCSCLA NVDNCVHIVA VLLKYHQMLV ESKRSFNLAE AFHLDCDQAE MLIENLSLEI 130 140 150 160 170 180 IAGGWNFKLG FTINLDKHNP QPSVLRFYCC DATFVYFLHL ENDTLHSVEL SKFKPEERAT 190 200 210 220 230 240 LLFFDKLCKQ FTVGYDRNSL LFPLAGFLKE LQANTEPTIF VFNDDKIDNI LFLRISKKHH 250 260 270 280 290 300 GLNHVCGFSG KKVFDFVTYK QKEKQIVLRS AYLSKFTDFK FPYTINIYKL QFGEPLFFYF 310 320 330 340 350 360 LIQLKRDGFK NFYFQSEDSI VKEKEYLPKL YFKVEYDPVK NKFVSDAFFK YKNHFNKGTT 370 380 390 400 410 420 TVYPHRYYMA KKSDRGGFNR LLFYEEAVEN FYQDQFDLGY FRKFEHLPIQ DKNQIEAFKA 430 440 450 460 470 480 ALDDLMPVDL AEVSLSDNLL HQKPLHFALS DLEAVAVDDK QIKLSFAPSA VELKLIKRIL 490 500 510 520 530 540 SAYHKGNVVC IDQESWYDLK QPAAKELIQF WNQFDLRNAT SDGNHIYLPK YYLFEVAKIF 550 560 570 580 590 600 SQYLDIKNLF DVPTIKKIED QNNNVFDLSL EHKKITSLRN YQQEGVKWIR GLEENKFGGI 610 620 630 640 650 660 LADEMGLGKT VQVIFALLDS YLKNHVNLPS LIIVPASLLL NWKSEFEKFA PQIKVKVANI 670 680 690 700 710 720 PSKERGELYE KLTNEILIVS FNVLRSDVKL ITKQRFHYVV IDEAQGIKND SSSITKAAKK 730 740 750 760 770 780 VKGNFCLALT GTPIENRLLD LWSCFDFVLP SFLGNKKQFT DQFEKEKTDQ SFHLLMQRTS 790 800 810 820 830 840 PFILRRTKSK VLKELPNKIT TDIYVELNPM HQKLYEEERD RGLEEIKQIQ DKSSFNILTL 850 860 870 880 890 900 ILKLRHLCSL PKNSQGILEN SAKKEAALEI IHEAIENQRK IILFTQFIDV IDHFKDTFKE 910 920 930 940 950 960 QGIEYFIFDG RKSPKSRHSI IEKFNNAKNP CVLLASLKAG GVGINLTAAE VVIHFDVWWN 970 980 990 1000 1010 1020 TAVENQATDR AHRIGQKKTV QVYRIIAKNT IEERVCQVQA EKQELVSKTL VEDVNFFESL 1030 TNEELLRLFE

References

[1]

"Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae." Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R. Nucleic Acids Res. 24:4420-4449(1996) [PubMed: 8948633] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29342 / M129.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U00089 Genomic DNA. Translation: AAB95782.1.
PIR	S73460.
RefSeq	NP_109708.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	876986.
GenomeReviews	Gene locus MPN_020 in contig U00089_GR.
KEGG	mpn:MPN020.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	P75093.
OMA	QVYRIIA
Enzyme and pathway databases
BioCyc	MPNE272634:MPN020-MON.
Family and domain databases
InterPro	IPR014001. DEAD-like_N. IPR001650. DNA/RNA_helicase_C. IPR014021. Helicase_SF1/SF2_ATP-bd. IPR000330. SNF2_N. IPR007527. Znf_SWIM. [Graphical view]
Pfam	PF00271. Helicase_C. 1 hit. PF00176. SNF2_N. 1 hit. PF04434. SWIM. 1 hit. [Graphical view]
SMART	SM00487. DEXDc. 1 hit. SM00490. HELICc. 1 hit. [Graphical view]
PROSITE	PS51192. HELICASE_ATP_BIND_1. 1 hit. PS51194. HELICASE_CTER. 1 hit. PS50966. ZF_SWIM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y020_MYCPN

Accession

Primary (citable) accession number: P75093

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	February 1, 1997
Last modified:	November 3, 2009
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)