P75053 (DEOD_MYCPN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Purine nucleoside phosphorylase deoD-type
Short name=PNP
EC=2.4.2.1

Gene names

Name:	deoD
Ordered Locus Names:	MPN_062
ORF Names:	MP092

Organism

Mycoplasma pneumoniae (strain ATCC 29342 / M129)

Taxonomic identifier

272634 [NCBI]

Taxonomic lineage

Bacteria › Tenericutes › Mollicutes › Mycoplasmataceae › Mycoplasma

Protein attributes

Sequence length	238 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate. HAMAP MF_01627
Subunit structure	Homohexamer By similarity. HAMAP MF_01627
Sequence similarities	Belongs to the PNP/UDP phosphorylase family.

Ontologies

Keywords
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	nucleoside metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	purine-nucleoside phosphorylase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 238	238	Purine nucleoside phosphorylase deoD-type HAMAP MF_01627		PRO_0000063148

Sequences

	Sequence		Length	Mass (Da)
	P75053 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 8F1A8E30F47FA5D9	FASTA	238	26,284
	10 20 30 40 50 60 MTPHINAKKD DIAKVVLMPG DPLRAKWIAE QFMEKPRLVN EVRGMLAFTG QYKGKTITIM 70 80 90 100 110 120 GHGMGIPSIG IYSYELMKFY EVNTIIRIGS CGALQGSLNL QDLIIAAKAW SESIYANDMG 130 140 150 160 170 180 VEVPADKILM ASPQLVELAK KTANQLQLAF HEGLVFCEDA FHQIRKDVLK LAQEKHALAV 190 200 210 220 230 EMEAHALYAN AMLLNKQALT MLTVSDSLVT HAALPAEQRQ ATFKNMAILS LEMASQLV

References

[1]	"Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae." Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R. Nucleic Acids Res. 24:4420-4449(1996) [PubMed: 8948633] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29342 / M129.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U00089 Genomic DNA. Translation: AAB95740.1.
PIR	S73418.
RefSeq	NP_109750.1. NC_000912.1.
3D structure databases
ProteinModelPortal	P75053.
ModBase	Search...
Protein-protein interaction databases
IntAct	P75053. 1 interaction.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	876955.
GenomeReviews	Gene locus MPN_062 in contig U00089_GR.
KEGG	mpn:MPN062.
PATRIC	20021403. VBIMycPne110_0063.
Phylogenomic databases
HOGENOM	HBG617197.
OMA	EPEIFEK.
PhylomeDB	P75053.
ProtClustDB	PRK05819.
Enzyme and pathway databases
BioCyc	MetaCyc:MONOMER-561. MPNE272634:MPN062-MONOMER.
Family and domain databases
HAMAP	MF_01627. Pur_nucleosid_phosp. [Tree]
InterPro	IPR004402. DeoD. IPR018017. Nucleoside_phosphorylase. IPR018016. Nucleoside_phosphorylase_CS. IPR000845. Nucleoside_phosphorylase_d. [Graphical view]
KO	K03784.
PANTHER	PTHR21234. PNP_UDP. 1 hit.
Pfam	PF01048. PNP_UDP_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR00107. DeoD. 1 hit.
PROSITE	PS01232. PNP_UDP_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DEOD_MYCPN

Accession

Primary (citable) accession number: P75053

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	February 1, 1997
Last modified:	January 25, 2012
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program