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P75053 (DEOD_MYCPN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Purine nucleoside phosphorylase DeoD-type

Short name=PNP
EC=2.4.2.1
Gene names
Name:deoD
Ordered Locus Names:MPN_062
ORF Names:MP092
OrganismMycoplasma pneumoniae (strain ATCC 29342 / M129) [Reference proteome] [HAMAP]
Taxonomic identifier272634 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length238 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate. HAMAP-Rule MF_01627

Purine deoxynucleoside + phosphate = purine + 2'-deoxy-alpha-D-ribose 1-phosphate. HAMAP-Rule MF_01627

Subunit structure

Homohexamer By similarity. HAMAP-Rule MF_01627

Sequence similarities

Belongs to the PNP/UDP phosphorylase family.

Ontologies

Keywords
   Molecular functionGlycosyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processnucleoside metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionpurine-nucleoside phosphorylase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 238238Purine nucleoside phosphorylase DeoD-type HAMAP-Rule MF_01627
PRO_0000063148

Sequences

Sequence LengthMass (Da)Tools
P75053 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 8F1A8E30F47FA5D9

FASTA23826,284
        10         20         30         40         50         60 
MTPHINAKKD DIAKVVLMPG DPLRAKWIAE QFMEKPRLVN EVRGMLAFTG QYKGKTITIM 

        70         80         90        100        110        120 
GHGMGIPSIG IYSYELMKFY EVNTIIRIGS CGALQGSLNL QDLIIAAKAW SESIYANDMG 

       130        140        150        160        170        180 
VEVPADKILM ASPQLVELAK KTANQLQLAF HEGLVFCEDA FHQIRKDVLK LAQEKHALAV 

       190        200        210        220        230 
EMEAHALYAN AMLLNKQALT MLTVSDSLVT HAALPAEQRQ ATFKNMAILS LEMASQLV 

« Hide

References

[1]"Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29342 / M129.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U00089 Genomic DNA. Translation: AAB95740.1.
PIRS73418.
RefSeqNP_109750.1. NC_000912.1.

3D structure databases

ProteinModelPortalP75053.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActP75053. 1 interaction.
STRING272634.MPN062.

Proteomic databases

PaxDbP75053.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB95740; AAB95740; MPN_062.
GeneID876955.
KEGGmpn:MPN062.
PATRIC20021403. VBIMycPne110_0063.

Phylogenomic databases

eggNOGCOG0813.
KOK03784.
OMASFETHAF.
OrthoDBEOG6BKJC5.
ProtClustDBPRK05819.

Enzyme and pathway databases

BioCycMetaCyc:MONOMER-561.
MPNE272634:GJ6Z-64-MONOMER.

Family and domain databases

Gene3D3.40.50.1580. 1 hit.
HAMAPMF_01627. Pur_nucleosid_phosp.
InterProIPR004402. DeoD-type.
IPR018017. Nucleoside_phosphorylase.
IPR018016. Nucleoside_phosphorylase_CS.
IPR000845. Nucleoside_phosphorylase_d.
[Graphical view]
PANTHERPTHR21234. PTHR21234. 1 hit.
PfamPF01048. PNP_UDP_1. 1 hit.
[Graphical view]
SUPFAMSSF53167. SSF53167. 1 hit.
TIGRFAMsTIGR00107. deoD. 1 hit.
PROSITEPS01232. PNP_UDP_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDEOD_MYCPN
AccessionPrimary (citable) accession number: P75053
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: April 16, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Mycoplasma pneumoniae

Mycoplasma pneumoniae (strain M129): entries and gene names