Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Purine nucleoside phosphorylase DeoD-type

Gene

deoD

Organism
Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate.
Purine deoxynucleoside + phosphate = purine + 2'-deoxy-alpha-D-ribose 1-phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei4 – 41Purine nucleoside; shared with dimeric partnerBy similarity
Binding sitei20 – 201Phosphate; via amide nitrogenBy similarity
Binding sitei24 – 241PhosphateBy similarity
Binding sitei43 – 431Phosphate; shared with dimeric partnerBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-561.
MPNE272634:GJ6Z-64-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Purine nucleoside phosphorylase DeoD-type (EC:2.4.2.1)
Short name:
PNP
Gene namesi
Name:deoD
Ordered Locus Names:MPN_062
ORF Names:MP092
OrganismiMycoplasma pneumoniae (strain ATCC 29342 / M129)
Taxonomic identifieri272634 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
Proteomesi
  • UP000000808 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 238238Purine nucleoside phosphorylase DeoD-typePRO_0000063148Add
BLAST

Interactioni

Subunit structurei

Homohexamer.By similarity

Protein-protein interaction databases

IntActiP75053. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliP75053.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni87 – 904Phosphate bindingBy similarity
Regioni181 – 1833Purine nucleoside bindingBy similarity
Regioni205 – 2062Purine nucleoside bindingBy similarity

Sequence similaritiesi

Belongs to the PNP/UDP phosphorylase family.Curated

Phylogenomic databases

KOiK03784.
OMAiAQNREYK.

Family and domain databases

Gene3Di3.40.50.1580. 1 hit.
HAMAPiMF_01627. Pur_nucleosid_phosp. 1 hit.
InterProiIPR004402. DeoD-type.
IPR018017. Nucleoside_phosphorylase.
IPR018016. Nucleoside_phosphorylase_CS.
IPR000845. Nucleoside_phosphorylase_d.
[Graphical view]
PANTHERiPTHR21234. PTHR21234. 1 hit.
PfamiPF01048. PNP_UDP_1. 1 hit.
[Graphical view]
SUPFAMiSSF53167. SSF53167. 1 hit.
TIGRFAMsiTIGR00107. deoD. 1 hit.
PROSITEiPS01232. PNP_UDP_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P75053-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPHINAKKD DIAKVVLMPG DPLRAKWIAE QFMEKPRLVN EVRGMLAFTG
60 70 80 90 100
QYKGKTITIM GHGMGIPSIG IYSYELMKFY EVNTIIRIGS CGALQGSLNL
110 120 130 140 150
QDLIIAAKAW SESIYANDMG VEVPADKILM ASPQLVELAK KTANQLQLAF
160 170 180 190 200
HEGLVFCEDA FHQIRKDVLK LAQEKHALAV EMEAHALYAN AMLLNKQALT
210 220 230
MLTVSDSLVT HAALPAEQRQ ATFKNMAILS LEMASQLV
Length:238
Mass (Da):26,284
Last modified:February 1, 1997 - v1
Checksum:i8F1A8E30F47FA5D9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00089 Genomic DNA. Translation: AAB95740.1.
PIRiS73418.
RefSeqiNP_109750.1. NC_000912.1.
WP_010874419.1. NC_000912.1.

Genome annotation databases

EnsemblBacteriaiAAB95740; AAB95740; MPN_062.
GeneIDi876955.
KEGGimpn:MPN062.
PATRICi20021403. VBIMycPne110_0063.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00089 Genomic DNA. Translation: AAB95740.1.
PIRiS73418.
RefSeqiNP_109750.1. NC_000912.1.
WP_010874419.1. NC_000912.1.

3D structure databases

ProteinModelPortaliP75053.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP75053. 1 interaction.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAB95740; AAB95740; MPN_062.
GeneIDi876955.
KEGGimpn:MPN062.
PATRICi20021403. VBIMycPne110_0063.

Phylogenomic databases

KOiK03784.
OMAiAQNREYK.

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-561.
MPNE272634:GJ6Z-64-MONOMER.

Family and domain databases

Gene3Di3.40.50.1580. 1 hit.
HAMAPiMF_01627. Pur_nucleosid_phosp. 1 hit.
InterProiIPR004402. DeoD-type.
IPR018017. Nucleoside_phosphorylase.
IPR018016. Nucleoside_phosphorylase_CS.
IPR000845. Nucleoside_phosphorylase_d.
[Graphical view]
PANTHERiPTHR21234. PTHR21234. 1 hit.
PfamiPF01048. PNP_UDP_1. 1 hit.
[Graphical view]
SUPFAMiSSF53167. SSF53167. 1 hit.
TIGRFAMsiTIGR00107. deoD. 1 hit.
PROSITEiPS01232. PNP_UDP_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDEOD_MYCPN
AccessioniPrimary (citable) accession number: P75053
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: September 7, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Mycoplasma pneumoniae
    Mycoplasma pneumoniae (strain M129): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.