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P75050

- MANB_MYCPN

UniProt

P75050 - MANB_MYCPN

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Protein
Phosphomannomutase
Gene
manB, cpsG, MPN_066, MP088
Organism
Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Alpha-D-mannose 1-phosphate = D-mannose 6-phosphate.

Cofactori

Binds 1 magnesium ion per subunit By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei149 – 1491Phosphoserine intermediate By similarity
Metal bindingi149 – 1491Magnesium; via phosphate group By similarity
Metal bindingi301 – 3011Magnesium By similarity
Metal bindingi303 – 3031Magnesium By similarity
Metal bindingi305 – 3051Magnesium By similarity

GO - Molecular functioni

  1. magnesium ion binding Source: InterPro
  2. phosphomannomutase activity Source: UniProtKB-EC

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Ligandi

Magnesium, Metal-binding

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-621.
MPNE272634:GJ6Z-68-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphomannomutase (EC:5.4.2.8)
Short name:
PMM
Gene namesi
Name:manB
Synonyms:cpsG
Ordered Locus Names:MPN_066
ORF Names:MP088
OrganismiMycoplasma pneumoniae (strain ATCC 29342 / M129)
Taxonomic identifieri272634 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
ProteomesiUP000000808: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 554554Phosphomannomutase
PRO_0000147830Add
BLAST

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP75050.

Interactioni

Protein-protein interaction databases

IntActiP75050. 3 interactions.
STRINGi272634.MPN066.

Structurei

3D structure databases

ProteinModelPortaliP75050.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1109.
KOiK01840.
OMAiFACEESH.
OrthoDBiEOG6103ZG.

Family and domain databases

Gene3Di3.30.310.50. 1 hit.
3.40.120.10. 3 hits.
InterProiIPR005844. A-D-PHexomutase_a/b/a-I.
IPR016055. A-D-PHexomutase_a/b/a-I/II/III.
IPR005845. A-D-PHexomutase_a/b/a-II.
IPR005846. A-D-PHexomutase_a/b/a-III.
IPR005843. A-D-PHexomutase_C.
IPR016066. A-D-PHexomutase_CS.
[Graphical view]
PfamiPF02878. PGM_PMM_I. 1 hit.
PF02879. PGM_PMM_II. 1 hit.
PF02880. PGM_PMM_III. 1 hit.
PF00408. PGM_PMM_IV. 1 hit.
[Graphical view]
SUPFAMiSSF53738. SSF53738. 3 hits.
SSF55957. SSF55957. 1 hit.
PROSITEiPS00710. PGM_PMM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P75050-1 [UniParc]FASTAAdd to Basket

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MNSNAYLEAQ RWLSHPRVKP NLKEVITAMS AEEIEHFFSL KKPSFGTAGV    50
RGKMAPGYHG MNVFSYAYLT QGYVNYIQSL NPTKKPLRFL VARDTRKHGA 100
LFNGIVCDVI TSMGHVVYMF DNNEPTPTPL VSYVIKKYHF DGGVNVTASH 150
NPKTDNGFKI YDGHGAQLLD FQTDQLIAML PPVVTMLDFE PRGNNELLHF 200
LDNEVVYKNY FDDLKESLVV DNDSFKNLPV VFTGLHGTSV KLLPRFLTYL 250
GYSNIISVQP QNVFDANFAN ADHLNPESKD TWELARQYAS NTKAKLMMAI 300
DPDADRFAIA EWNPQTQDWH YFSGNESGVM VAYYKLKHKQ FKRQPYIVTT 350
VVSTDLVDKI AKKYGAFVKR TNVGFKFIGQ AVNHFSKDNE LVVAFEEAIG 400
MMASDGLNRE KDSFQAAAIM LEIARYCHNK GISLLEFYRG EIFGEFGDYY 450
NWTVPHTIHG VNWKEKMEQV LHQLTTATIK EVVGHKITKI KNYVDINLVE 500
YVLENGNWIK FRISGTEPKL KLYFNLSNGY LAALKHEAKK MHEFLVRLLN 550
LDKA 554
Length:554
Mass (Da):63,215
Last modified:February 1, 1997 - v1
Checksum:i9993A52B3D5E6C0B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00089 Genomic DNA. Translation: AAB95736.1.
PIRiS73414.
RefSeqiNP_109754.1. NC_000912.1.

Genome annotation databases

EnsemblBacteriaiAAB95736; AAB95736; MPN_066.
GeneIDi876721.
KEGGimpn:MPN066.
PATRICi20021411. VBIMycPne110_0067.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00089 Genomic DNA. Translation: AAB95736.1 .
PIRi S73414.
RefSeqi NP_109754.1. NC_000912.1.

3D structure databases

ProteinModelPortali P75050.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi P75050. 3 interactions.
STRINGi 272634.MPN066.

Proteomic databases

PaxDbi P75050.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAB95736 ; AAB95736 ; MPN_066 .
GeneIDi 876721.
KEGGi mpn:MPN066.
PATRICi 20021411. VBIMycPne110_0067.

Phylogenomic databases

eggNOGi COG1109.
KOi K01840.
OMAi FACEESH.
OrthoDBi EOG6103ZG.

Enzyme and pathway databases

BioCyci MetaCyc:MONOMER-621.
MPNE272634:GJ6Z-68-MONOMER.

Family and domain databases

Gene3Di 3.30.310.50. 1 hit.
3.40.120.10. 3 hits.
InterProi IPR005844. A-D-PHexomutase_a/b/a-I.
IPR016055. A-D-PHexomutase_a/b/a-I/II/III.
IPR005845. A-D-PHexomutase_a/b/a-II.
IPR005846. A-D-PHexomutase_a/b/a-III.
IPR005843. A-D-PHexomutase_C.
IPR016066. A-D-PHexomutase_CS.
[Graphical view ]
Pfami PF02878. PGM_PMM_I. 1 hit.
PF02879. PGM_PMM_II. 1 hit.
PF02880. PGM_PMM_III. 1 hit.
PF00408. PGM_PMM_IV. 1 hit.
[Graphical view ]
SUPFAMi SSF53738. SSF53738. 3 hits.
SSF55957. SSF55957. 1 hit.
PROSITEi PS00710. PGM_PMM. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
    Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
    Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29342 / M129.

Entry informationi

Entry nameiMANB_MYCPN
AccessioniPrimary (citable) accession number: P75050
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: May 14, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Mycoplasma pneumoniae
    Mycoplasma pneumoniae (strain M129): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi