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Protein

Phosphomannomutase

Gene

manB

Organism
Mycoplasma pneumoniae (strain ATCC 29342 / M129)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Alpha-D-mannose 1-phosphate = D-mannose 6-phosphate.

Cofactori

Mg2+By similarityNote: Binds 1 Mg2+ ion per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei149Phosphoserine intermediateBy similarity1
Metal bindingi149Magnesium; via phosphate groupBy similarity1
Metal bindingi301MagnesiumBy similarity1
Metal bindingi303MagnesiumBy similarity1
Metal bindingi305MagnesiumBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
LigandMagnesium, Metal-binding

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-621
MPNE272634:G1GJ3-103-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphomannomutase (EC:5.4.2.8)
Short name:
PMM
Gene namesi
Name:manB
Synonyms:cpsG
Ordered Locus Names:MPN_066
ORF Names:MP088
OrganismiMycoplasma pneumoniae (strain ATCC 29342 / M129)
Taxonomic identifieri272634 [NCBI]
Taxonomic lineageiBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma
Proteomesi
  • UP000000808 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001478301 – 554PhosphomannomutaseAdd BLAST554

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiP75050

Interactioni

Protein-protein interaction databases

IntActiP75050, 3 interactors

Structurei

3D structure databases

ProteinModelPortaliP75050
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the phosphohexose mutase family.Curated

Phylogenomic databases

KOiK01840
OMAiAIGYMCC

Family and domain databases

InterProiView protein in InterPro
IPR005844 A-D-PHexomutase_a/b/a-I
IPR016055 A-D-PHexomutase_a/b/a-I/II/III
IPR005845 A-D-PHexomutase_a/b/a-II
IPR005846 A-D-PHexomutase_a/b/a-III
IPR005843 A-D-PHexomutase_C
IPR036900 A-D-PHexomutase_C_sf
IPR016066 A-D-PHexomutase_CS
PfamiView protein in Pfam
PF02878 PGM_PMM_I, 1 hit
PF02879 PGM_PMM_II, 1 hit
PF02880 PGM_PMM_III, 1 hit
PF00408 PGM_PMM_IV, 1 hit
SUPFAMiSSF53738 SSF53738, 3 hits
SSF55957 SSF55957, 1 hit
PROSITEiView protein in PROSITE
PS00710 PGM_PMM, 1 hit

Sequencei

Sequence statusi: Complete.

P75050-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSNAYLEAQ RWLSHPRVKP NLKEVITAMS AEEIEHFFSL KKPSFGTAGV
60 70 80 90 100
RGKMAPGYHG MNVFSYAYLT QGYVNYIQSL NPTKKPLRFL VARDTRKHGA
110 120 130 140 150
LFNGIVCDVI TSMGHVVYMF DNNEPTPTPL VSYVIKKYHF DGGVNVTASH
160 170 180 190 200
NPKTDNGFKI YDGHGAQLLD FQTDQLIAML PPVVTMLDFE PRGNNELLHF
210 220 230 240 250
LDNEVVYKNY FDDLKESLVV DNDSFKNLPV VFTGLHGTSV KLLPRFLTYL
260 270 280 290 300
GYSNIISVQP QNVFDANFAN ADHLNPESKD TWELARQYAS NTKAKLMMAI
310 320 330 340 350
DPDADRFAIA EWNPQTQDWH YFSGNESGVM VAYYKLKHKQ FKRQPYIVTT
360 370 380 390 400
VVSTDLVDKI AKKYGAFVKR TNVGFKFIGQ AVNHFSKDNE LVVAFEEAIG
410 420 430 440 450
MMASDGLNRE KDSFQAAAIM LEIARYCHNK GISLLEFYRG EIFGEFGDYY
460 470 480 490 500
NWTVPHTIHG VNWKEKMEQV LHQLTTATIK EVVGHKITKI KNYVDINLVE
510 520 530 540 550
YVLENGNWIK FRISGTEPKL KLYFNLSNGY LAALKHEAKK MHEFLVRLLN

LDKA
Length:554
Mass (Da):63,215
Last modified:February 1, 1997 - v1
Checksum:i9993A52B3D5E6C0B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00089 Genomic DNA Translation: AAB95736.1
PIRiS73414
RefSeqiNP_109754.1, NC_000912.1
WP_010874423.1, NC_000912.1

Genome annotation databases

EnsemblBacteriaiAAB95736; AAB95736; MPN_066
GeneIDi876721
KEGGimpn:MPN066
PATRICifig|272634.6.peg.67

Similar proteinsi

Entry informationi

Entry nameiMANB_MYCPN
AccessioniPrimary (citable) accession number: P75050
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: May 23, 2018
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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