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P75046 (RSMI_MYCPN) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribosomal RNA small subunit methyltransferase I

EC=2.1.1.198
Alternative name(s):
16S rRNA 2'-O-ribose C1402 methyltransferase
rRNA (cytidine-2'-O-)-methyltransferase RsmI
Gene names
Name:rsmI
Ordered Locus Names:MPN_071
ORF Names:D09_orf276, MP084
OrganismMycoplasma pneumoniae (strain ATCC 29342 / M129) [Reference proteome] [HAMAP]
Taxonomic identifier272634 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length276 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA By similarity. HAMAP-Rule MF_01877

Catalytic activity

S-adenosyl-L-methionine + cytidine(1402) in 16S rRNA = S-adenosyl-L-homocysteine + 2'-O-methylcytidine(1402) in 16S rRNA. HAMAP-Rule MF_01877

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_01877.

Sequence similarities

Belongs to the methyltransferase superfamily. RsmI family.

Ontologies

Keywords
   Biological processrRNA processing
   Cellular componentCytoplasm
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processrRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmethyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 276276Ribosomal RNA small subunit methyltransferase I HAMAP-Rule MF_01877
PRO_0000211944

Sequences

Sequence LengthMass (Da)Tools
P75046 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 2A071E7A17FCD0CD

FASTA27631,062
        10         20         30         40         50         60 
MPALKVIATP IGNIEEVSPR VKAALTKCEV LFCEDTRVTK KLLGLLGIDF SNKQFIINNE 

        70         80         90        100        110        120 
FKEKQNLSKV ANLIHQYHCG LVSDAGYPSV SDPGHILVEY VRTQLPQIAI EVINGPSALV 

       130        140        150        160        170        180 
CGLVTSGFPE SPLLFLGFLD HKPTQVTQTL KHYQNFQGTI VLFEAVHRLQ QTLEVIQTVF 

       190        200        210        220        230        240 
SNTEVFVGRE LTKLHESHYW FNTSAPLPDI TLKGEFVIVI NNHHTQPVGQ YSDQLLKQEI 

       250        260        270 
TQLVQMGVKV KDACHYLAKR LQLKSNKLYT LFHESD 

« Hide

References

[1]"Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae."
Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.
Nucleic Acids Res. 24:4420-4449(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29342 / M129.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U00089 Genomic DNA. Translation: AAB95732.1.
PIRS73410.
RefSeqNP_109759.1. NC_000912.1.

3D structure databases

ProteinModelPortalP75046.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272634.MPN071.

Proteomic databases

PaxDbP75046.
PRIDEP75046.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAB95732; AAB95732; MPN_071.
GeneID877160.
KEGGmpn:MPN071.
PATRIC20021421. VBIMycPne110_0072.

Phylogenomic databases

eggNOGCOG0313.
KOK07056.
OMASHNDREF.
OrthoDBEOG6677TH.

Enzyme and pathway databases

BioCycMPNE272634:GJ6Z-73-MONOMER.

Family and domain databases

Gene3D3.30.950.10. 1 hit.
3.40.1010.10. 1 hit.
HAMAPMF_01877. 16SrRNA_methyltr_I.
InterProIPR000878. 4pyrrol_Mease.
IPR014777. 4pyrrole_Mease_sub1.
IPR014776. 4pyrrole_Mease_sub2.
IPR008189. rRNA_ssu_MeTfrase_I.
IPR018063. SAM_MeTrfase_RsmI_CS.
[Graphical view]
PfamPF00590. TP_methylase. 1 hit.
[Graphical view]
PIRSFPIRSF005917. MTase_YraL. 1 hit.
SUPFAMSSF53790. SSF53790. 1 hit.
TIGRFAMsTIGR00096. TIGR00096. 1 hit.
PROSITEPS01296. RSMI. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRSMI_MYCPN
AccessionPrimary (citable) accession number: P75046
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: June 11, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Mycoplasma pneumoniae

Mycoplasma pneumoniae (strain M129): entries and gene names