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P75028

- PCXA_SYNY3

UniProt

P75028 - PCXA_SYNY3

Protein

Proton extrusion protein PcxA

Gene

pcxA

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 94 (01 Oct 2014)
      Sequence version 1 (01 Feb 1997)
      Previous versions | rss
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    Functioni

    Involved in light-induced Na+-dependent proton extrusion. Also seems to be involved in CO2 transport.

    GO - Molecular functioni

    1. hydrogen ion transmembrane transporter activity Source: UniProtKB-HAMAP

    Keywords - Biological processi

    Hydrogen ion transport, Ion transport, Transport

    Protein family/group databases

    TCDBi9.B.73.1.2. chloroplast envelope/cyanobacterial membrane protein (cema) family.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Proton extrusion protein PcxA
    Gene namesi
    Name:pcxA
    Synonyms:cotA
    Ordered Locus Names:slr1596
    OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
    Taxonomic identifieri1111708 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
    ProteomesiUP000001425: Chromosome

    Subcellular locationi

    Cell inner membrane 1 Publication; Multi-pass membrane protein 1 Publication

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 440440Proton extrusion protein PcxAPRO_0000216670Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    IntActiP75028. 16 interactions.
    STRINGi1148.slr1596.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei217 – 23620HelicalSequence AnalysisAdd
    BLAST
    Transmembranei317 – 33923HelicalSequence AnalysisAdd
    BLAST
    Transmembranei352 – 37423HelicalSequence AnalysisAdd
    BLAST
    Transmembranei402 – 42120HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the Cema family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG06592.
    HOGENOMiHOG000037065.
    OMAiVFVGFHS.
    OrthoDBiEOG664CDD.
    PhylomeDBiP75028.

    Family and domain databases

    HAMAPiMF_01308. CemA.
    InterProiIPR004282. CemA.
    [Graphical view]
    PfamiPF03040. CemA. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P75028-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDLTNWWQGA TQWFGRSSQK SLEQAFRSAL KIKEIEDQYF QGKKIGPENC    50
    DYSADTVTYF ANQIQRHLRK IEQEIYHLNS DQEFVKILSL DPAVKQDPQT 100
    EYVLNQLQFI DDILQRYDGE LPQVSPPKQI ANGGVLDLPA ITANKQRQIN 150
    KKRRDGFQYI RREDTQQKVD TATQKSGVLP RSFLRTIDRL KREMDPQSSD 200
    TEQKVLKQYR NSRYKTALSI KFVLTLIIVP LLAHQLTKTF FLLPSVESFF 250
    ERNSEVVFIN QSMETEAYEE LSHFEESLRF RELLGFGEKL SPEAKEEKLA 300
    EKAKEISESY RRVSTNAIAN IFADIFSLVA FSLVLVNSQR EIEVLKEFID 350
    EIVYGLSDSA KAFLIILFTD MFVGFHSPHG WEVILASIAR HFGLPENQDF 400
    NFLFIATFPV ILDTVFKYWI FRYLNSISPS AVATYRNMNE 440
    Length:440
    Mass (Da):51,117
    Last modified:February 1, 1997 - v1
    Checksum:i67105B2ABEB13452
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D63838 Genomic DNA. Translation: BAA09896.1.
    BA000022 Genomic DNA. Translation: BAA16993.1.
    PIRiS74953.
    RefSeqiNP_440313.1. NC_000911.1.
    YP_005650370.1. NC_017277.1.
    YP_007450196.1. NC_020286.1.

    Genome annotation databases

    EnsemblBacteriaiBAA16993; BAA16993; BAA16993.
    GeneIDi953612.
    KEGGisyn:slr1596.
    syy:SYNGTS_0417.
    syz:MYO_14220.
    PATRICi23837766. VBISynSp132158_0452.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D63838 Genomic DNA. Translation: BAA09896.1 .
    BA000022 Genomic DNA. Translation: BAA16993.1 .
    PIRi S74953.
    RefSeqi NP_440313.1. NC_000911.1.
    YP_005650370.1. NC_017277.1.
    YP_007450196.1. NC_020286.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi P75028. 16 interactions.
    STRINGi 1148.slr1596.

    Protein family/group databases

    TCDBi 9.B.73.1.2. chloroplast envelope/cyanobacterial membrane protein (cema) family.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAA16993 ; BAA16993 ; BAA16993 .
    GeneIDi 953612.
    KEGGi syn:slr1596.
    syy:SYNGTS_0417.
    syz:MYO_14220.
    PATRICi 23837766. VBISynSp132158_0452.

    Phylogenomic databases

    eggNOGi NOG06592.
    HOGENOMi HOG000037065.
    OMAi VFVGFHS.
    OrthoDBi EOG664CDD.
    PhylomeDBi P75028.

    Family and domain databases

    HAMAPi MF_01308. CemA.
    InterProi IPR004282. CemA.
    [Graphical view ]
    Pfami PF03040. CemA. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "cemA homologue essential to CO2 transport in the cyanobacterium Synechocystis PCC6803."
      Katoh A., Lee K.S., Fukuzawa H., Ohyama K., Ogawa T.
      Proc. Natl. Acad. Sci. U.S.A. 93:4006-4010(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. "Size of cotA and identification of the gene product in Synechocystis sp. strain PCC6803."
      Sonoda M., Kitano K., Katoh A., Katoh H., Ohkawa H., Ogawa T.
      J. Bacteriol. 179:3845-3850(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: SEQUENCE REVISION TO N-TERMINUS, SUBCELLULAR LOCATION.
    3. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
      Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
      , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
      DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PCC 6803 / Kazusa.
    4. "Absence of light-induced proton extrusion in a cotA-less mutant of Synechocystis sp. strain PCC6803."
      Katoh A., Sonoda M., Katoh H., Ogawa T.
      J. Bacteriol. 178:5452-5455(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: CHARACTERIZATION.
    5. "Photosynthetic electron transport involved in PxcA-dependent proton extrusion in Synechocystis sp. Strain PCC6803: effect of pxcA inactivation on CO2, HCO3-, and NO3- uptake."
      Sonoda M., Katoh H., Vermaas W., Schmetterer G., Ogawa T.
      J. Bacteriol. 180:3799-3803(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: CHARACTERIZATION.

    Entry informationi

    Entry nameiPCXA_SYNY3
    AccessioniPrimary (citable) accession number: P75028
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 1, 2001
    Last sequence update: February 1, 1997
    Last modified: October 1, 2014
    This is version 94 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Synechocystis PCC 6803
      Synechocystis (strain PCC 6803): entries and gene names

    External Data

    Dasty 3