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P75028

- PCXA_SYNY3

UniProt

P75028 - PCXA_SYNY3

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Protein

Proton extrusion protein PcxA

Gene

pcxA

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli

Functioni

Involved in light-induced Na+-dependent proton extrusion. Also seems to be involved in CO2 transport.

GO - Molecular functioni

  1. hydrogen ion transmembrane transporter activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

Hydrogen ion transport, Ion transport, Transport

Protein family/group databases

TCDBi9.B.73.1.2. chloroplast envelope/cyanobacterial membrane protein (cema) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Proton extrusion protein PcxA
Gene namesi
Name:pcxA
Synonyms:cotA
Ordered Locus Names:slr1596
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
ProteomesiUP000001425: Chromosome

Subcellular locationi

Cell inner membrane 1 Publication; Multi-pass membrane protein 1 Publication

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 440440Proton extrusion protein PcxAPRO_0000216670Add
BLAST

Interactioni

Protein-protein interaction databases

IntActiP75028. 16 interactions.
STRINGi1148.slr1596.

Structurei

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei217 – 23620HelicalSequence AnalysisAdd
BLAST
Transmembranei317 – 33923HelicalSequence AnalysisAdd
BLAST
Transmembranei352 – 37423HelicalSequence AnalysisAdd
BLAST
Transmembranei402 – 42120HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the Cema family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG06592.
HOGENOMiHOG000037065.
InParanoidiP75028.
OMAiVFVGFHS.
OrthoDBiEOG664CDD.
PhylomeDBiP75028.

Family and domain databases

HAMAPiMF_01308. CemA.
InterProiIPR004282. CemA.
[Graphical view]
PfamiPF03040. CemA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P75028-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDLTNWWQGA TQWFGRSSQK SLEQAFRSAL KIKEIEDQYF QGKKIGPENC
60 70 80 90 100
DYSADTVTYF ANQIQRHLRK IEQEIYHLNS DQEFVKILSL DPAVKQDPQT
110 120 130 140 150
EYVLNQLQFI DDILQRYDGE LPQVSPPKQI ANGGVLDLPA ITANKQRQIN
160 170 180 190 200
KKRRDGFQYI RREDTQQKVD TATQKSGVLP RSFLRTIDRL KREMDPQSSD
210 220 230 240 250
TEQKVLKQYR NSRYKTALSI KFVLTLIIVP LLAHQLTKTF FLLPSVESFF
260 270 280 290 300
ERNSEVVFIN QSMETEAYEE LSHFEESLRF RELLGFGEKL SPEAKEEKLA
310 320 330 340 350
EKAKEISESY RRVSTNAIAN IFADIFSLVA FSLVLVNSQR EIEVLKEFID
360 370 380 390 400
EIVYGLSDSA KAFLIILFTD MFVGFHSPHG WEVILASIAR HFGLPENQDF
410 420 430 440
NFLFIATFPV ILDTVFKYWI FRYLNSISPS AVATYRNMNE
Length:440
Mass (Da):51,117
Last modified:February 1, 1997 - v1
Checksum:i67105B2ABEB13452
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D63838 Genomic DNA. Translation: BAA09896.1.
BA000022 Genomic DNA. Translation: BAA16993.1.
PIRiS74953.
RefSeqiNP_440313.1. NC_000911.1.
YP_005650370.1. NC_017277.1.
YP_007450196.1. NC_020286.1.

Genome annotation databases

EnsemblBacteriaiBAA16993; BAA16993; BAA16993.
GeneIDi953612.
KEGGisyn:slr1596.
syy:SYNGTS_0417.
syz:MYO_14220.
PATRICi23837766. VBISynSp132158_0452.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D63838 Genomic DNA. Translation: BAA09896.1 .
BA000022 Genomic DNA. Translation: BAA16993.1 .
PIRi S74953.
RefSeqi NP_440313.1. NC_000911.1.
YP_005650370.1. NC_017277.1.
YP_007450196.1. NC_020286.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi P75028. 16 interactions.
STRINGi 1148.slr1596.

Protein family/group databases

TCDBi 9.B.73.1.2. chloroplast envelope/cyanobacterial membrane protein (cema) family.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAA16993 ; BAA16993 ; BAA16993 .
GeneIDi 953612.
KEGGi syn:slr1596.
syy:SYNGTS_0417.
syz:MYO_14220.
PATRICi 23837766. VBISynSp132158_0452.

Phylogenomic databases

eggNOGi NOG06592.
HOGENOMi HOG000037065.
InParanoidi P75028.
OMAi VFVGFHS.
OrthoDBi EOG664CDD.
PhylomeDBi P75028.

Family and domain databases

HAMAPi MF_01308. CemA.
InterProi IPR004282. CemA.
[Graphical view ]
Pfami PF03040. CemA. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "cemA homologue essential to CO2 transport in the cyanobacterium Synechocystis PCC6803."
    Katoh A., Lee K.S., Fukuzawa H., Ohyama K., Ogawa T.
    Proc. Natl. Acad. Sci. U.S.A. 93:4006-4010(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Size of cotA and identification of the gene product in Synechocystis sp. strain PCC6803."
    Sonoda M., Kitano K., Katoh A., Katoh H., Ohkawa H., Ogawa T.
    J. Bacteriol. 179:3845-3850(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: SEQUENCE REVISION TO N-TERMINUS, SUBCELLULAR LOCATION.
  3. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / Kazusa.
  4. "Absence of light-induced proton extrusion in a cotA-less mutant of Synechocystis sp. strain PCC6803."
    Katoh A., Sonoda M., Katoh H., Ogawa T.
    J. Bacteriol. 178:5452-5455(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: CHARACTERIZATION.
  5. "Photosynthetic electron transport involved in PxcA-dependent proton extrusion in Synechocystis sp. Strain PCC6803: effect of pxcA inactivation on CO2, HCO3-, and NO3- uptake."
    Sonoda M., Katoh H., Vermaas W., Schmetterer G., Ogawa T.
    J. Bacteriol. 180:3799-3803(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: CHARACTERIZATION.

Entry informationi

Entry nameiPCXA_SYNY3
AccessioniPrimary (citable) accession number: P75028
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: February 1, 1997
Last modified: October 29, 2014
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

External Data

Dasty 3