Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P75028 (PCXA_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 91. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Proton extrusion protein PcxA
Gene names
Name:pcxA
Synonyms:cotA
Ordered Locus Names:slr1596
OrganismSynechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]
Taxonomic identifier1111708 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis

Protein attributes

Sequence length440 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Involved in light-induced Na+-dependent proton extrusion. Also seems to be involved in CO2 transport. HAMAP-Rule MF_01308

Subcellular location

Cell inner membrane; Multi-pass membrane protein Ref.2.

Sequence similarities

Belongs to the Cema family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 440440Proton extrusion protein PcxA HAMAP-Rule MF_01308
PRO_0000216670

Regions

Transmembrane217 – 23620Helical; Potential
Transmembrane317 – 33923Helical; Potential
Transmembrane352 – 37423Helical; Potential
Transmembrane402 – 42120Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P75028 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 67105B2ABEB13452

FASTA44051,117
        10         20         30         40         50         60 
MDLTNWWQGA TQWFGRSSQK SLEQAFRSAL KIKEIEDQYF QGKKIGPENC DYSADTVTYF 

        70         80         90        100        110        120 
ANQIQRHLRK IEQEIYHLNS DQEFVKILSL DPAVKQDPQT EYVLNQLQFI DDILQRYDGE 

       130        140        150        160        170        180 
LPQVSPPKQI ANGGVLDLPA ITANKQRQIN KKRRDGFQYI RREDTQQKVD TATQKSGVLP 

       190        200        210        220        230        240 
RSFLRTIDRL KREMDPQSSD TEQKVLKQYR NSRYKTALSI KFVLTLIIVP LLAHQLTKTF 

       250        260        270        280        290        300 
FLLPSVESFF ERNSEVVFIN QSMETEAYEE LSHFEESLRF RELLGFGEKL SPEAKEEKLA 

       310        320        330        340        350        360 
EKAKEISESY RRVSTNAIAN IFADIFSLVA FSLVLVNSQR EIEVLKEFID EIVYGLSDSA 

       370        380        390        400        410        420 
KAFLIILFTD MFVGFHSPHG WEVILASIAR HFGLPENQDF NFLFIATFPV ILDTVFKYWI 

       430        440 
FRYLNSISPS AVATYRNMNE 

« Hide

References

« Hide 'large scale' references
[1]"cemA homologue essential to CO2 transport in the cyanobacterium Synechocystis PCC6803."
Katoh A., Lee K.S., Fukuzawa H., Ohyama K., Ogawa T.
Proc. Natl. Acad. Sci. U.S.A. 93:4006-4010(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Size of cotA and identification of the gene product in Synechocystis sp. strain PCC6803."
Sonoda M., Kitano K., Katoh A., Katoh H., Ohkawa H., Ogawa T.
J. Bacteriol. 179:3845-3850(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: SEQUENCE REVISION TO N-TERMINUS, SUBCELLULAR LOCATION.
[3]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. expand/collapse author list , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 6803 / Kazusa.
[4]"Absence of light-induced proton extrusion in a cotA-less mutant of Synechocystis sp. strain PCC6803."
Katoh A., Sonoda M., Katoh H., Ogawa T.
J. Bacteriol. 178:5452-5455(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: CHARACTERIZATION.
[5]"Photosynthetic electron transport involved in PxcA-dependent proton extrusion in Synechocystis sp. Strain PCC6803: effect of pxcA inactivation on CO2, HCO3-, and NO3- uptake."
Sonoda M., Katoh H., Vermaas W., Schmetterer G., Ogawa T.
J. Bacteriol. 180:3799-3803(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: CHARACTERIZATION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D63838 Genomic DNA. Translation: BAA09896.1.
BA000022 Genomic DNA. Translation: BAA16993.1.
PIRS74953.
RefSeqNP_440313.1. NC_000911.1.
YP_005650370.1. NC_017277.1.
YP_007450196.1. NC_020286.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActP75028. 16 interactions.
STRING1148.slr1596.

Protein family/group databases

TCDB9.B.73.1.2. chloroplast envelope/cyanobacterial membrane protein (cema) family.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA16993; BAA16993; BAA16993.
GeneID12256060.
14615844.
953612.
KEGGsyn:slr1596.
syy:SYNGTS_0417.
syz:MYO_14220.
PATRIC23837766. VBISynSp132158_0452.

Phylogenomic databases

eggNOGNOG06592.
HOGENOMHOG000037065.
OMAILFTDVF.
OrthoDBEOG664CDD.
PhylomeDBP75028.
ProtClustDBPRK02507.

Family and domain databases

HAMAPMF_01308. CemA.
InterProIPR004282. CemA.
[Graphical view]
PfamPF03040. CemA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePCXA_SYNY3
AccessionPrimary (citable) accession number: P75028
Entry history
Integrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: February 1, 1997
Last modified: April 16, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Synechocystis PCC 6803

Synechocystis (strain PCC 6803): entries and gene names

SIMILARITY comments

Index of protein domains and families