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Protein

Flagellar motor switch protein FliM

Gene

fliM

Organism
Treponema pallidum (strain Nichols)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Chemotaxis, Flagellar rotation

Names & Taxonomyi

Protein namesi
Recommended name:
Flagellar motor switch protein FliM
Gene namesi
Name:fliM
Ordered Locus Names:TP_0721
OrganismiTreponema pallidum (strain Nichols)
Taxonomic identifieri243276 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeTreponema
Proteomesi
  • UP000000811 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Bacterial flagellum, Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001809321 – 344Flagellar motor switch protein FliMAdd BLAST344

Interactioni

Protein-protein interaction databases

IntActiP74927. 4 interactors.
MINTiMINT-6480471.
STRINGi243276.TP0721.

Structurei

3D structure databases

ProteinModelPortaliP74927.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FliM family.Curated

Phylogenomic databases

eggNOGiENOG4105D24. Bacteria.
COG1868. LUCA.
KOiK02416.
OMAiNPQFTQI.

Family and domain databases

Gene3Di3.40.1550.10. 1 hit.
InterProiIPR028976. CheC-like_dom.
IPR001689. Flag_FliM.
IPR001543. SpoA.
[Graphical view]
PfamiPF02154. FliM. 1 hit.
PF01052. FliMN_C. 1 hit.
[Graphical view]
PIRSFiPIRSF002888. FliM. 1 hit.
PRINTSiPR00955. FLGMOTORFLIM.
SUPFAMiSSF101801. SSF101801. 1 hit.
SSF103039. SSF103039. 1 hit.
TIGRFAMsiTIGR01397. fliM_switch. 1 hit.

Sequencei

Sequence statusi: Complete.

P74927-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTEVLSQDEI DQLLTAISSG DASIEDARPI SDTRKITLYD FRRPDKFSKE
60 70 80 90 100
QMRTLSLMHE TFARLTTTSL SAQLRSMVHV HVASVDQLTY EEFIRSIPTP
110 120 130 140 150
STLAVITMDP LKGNAVLEVD PSITFSIIDR LFGGTGQAAK VQRDLTDIEN
160 170 180 190 200
SVMEGVIVRI LANVRESWTQ VIDLRPRLGQ IETNPQFAQI VPPSEMVVLV
210 220 230 240 250
TLETKVGEEE GMMNFCIPYI TIEPIISKLS SQFWFSSVRR SSTTQYMGVL
260 270 280 290 300
RDKLSTVDMD VVAEVGSLRL SVRDILGLRV GDIIRLHDTH VGDPFVLSIG
310 320 330 340
NRKKFLCQPG VVGKKIAAQI LERIESTSQE DFEELSADEE ELYE
Length:344
Mass (Da):38,553
Last modified:January 1, 1998 - v2
Checksum:iA2AC419677449737
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28219 Genomic DNA. Translation: AAB61256.1.
AE000520 Genomic DNA. Translation: AAC65687.1.
U36839 Genomic DNA. Translation: AAB00543.1.
PIRiE71291.
RefSeqiWP_010882166.1. NC_021490.2.

Genome annotation databases

EnsemblBacteriaiAAC65687; AAC65687; TP_0721.
GeneIDi2611014.
KEGGitpa:TP_0721.
PATRICi20531533. VBITrePal57110_0766.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28219 Genomic DNA. Translation: AAB61256.1.
AE000520 Genomic DNA. Translation: AAC65687.1.
U36839 Genomic DNA. Translation: AAB00543.1.
PIRiE71291.
RefSeqiWP_010882166.1. NC_021490.2.

3D structure databases

ProteinModelPortaliP74927.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP74927. 4 interactors.
MINTiMINT-6480471.
STRINGi243276.TP0721.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC65687; AAC65687; TP_0721.
GeneIDi2611014.
KEGGitpa:TP_0721.
PATRICi20531533. VBITrePal57110_0766.

Phylogenomic databases

eggNOGiENOG4105D24. Bacteria.
COG1868. LUCA.
KOiK02416.
OMAiNPQFTQI.

Family and domain databases

Gene3Di3.40.1550.10. 1 hit.
InterProiIPR028976. CheC-like_dom.
IPR001689. Flag_FliM.
IPR001543. SpoA.
[Graphical view]
PfamiPF02154. FliM. 1 hit.
PF01052. FliMN_C. 1 hit.
[Graphical view]
PIRSFiPIRSF002888. FliM. 1 hit.
PRINTSiPR00955. FLGMOTORFLIM.
SUPFAMiSSF101801. SSF101801. 1 hit.
SSF103039. SSF103039. 1 hit.
TIGRFAMsiTIGR01397. fliM_switch. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiFLIM_TREPA
AccessioniPrimary (citable) accession number: P74927
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: January 1, 1998
Last modified: November 2, 2016
This is version 102 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.