P74903 (VATF_THET8) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
V-type ATP synthase subunit F

Alternative name(s):
V-ATPase subunit F

Gene names

Name:	atpF
Synonyms:	vatF
Ordered Locus Names:	TTHA1274

Organism

Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)

Taxonomic identifier

300852 [NCBI]

Taxonomic lineage

Bacteria › Deinococcus-Thermus › Deinococci › Thermales › Thermaceae › Thermus

Protein attributes

Sequence length	104 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Produces ATP from ADP in the presence of a proton gradient across the membrane. HAMAP MF_00312
Sequence similarities	Belongs to the V-ATPase F subunit family.

Ontologies

Keywords
Biological process	ATP synthesis Hydrogen ion transport Ion transport Transport
Technical term	3D-structure Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	ATP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW ATP hydrolysis coupled proton transport Inferred from electronic annotation. Source: InterPro
Cellular component	proton-transporting two-sector ATPase complex, catalytic domain Inferred from electronic annotation. Source: InterPro
Molecular function	hydrogen ion transporting ATP synthase activity, rotational mechanism Inferred from electronic annotation. Source: InterPro proton-transporting ATPase activity, rotational mechanism Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 104

104

V-type ATP synthase subunit F HAMAP MF_00312

PRO_0000144829

Secondary structure

1

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104

Helix Strand Turn

Details...

Beta strand

1 – 5

5

Helix

7 – 15

9

Beta strand

18 – 22

5

Helix

26 – 39

14

Beta strand

43 – 48

6

Turn

49 – 51

3

Helix

55 – 62

8

Beta strand

70 – 75

6

Helix

77 – 81

5

Beta strand

82 – 84

3

Helix

86 – 98

13

Sequences

	Sequence		Length	Mass (Da)
	P74903 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 6679E33E27E102E1	FASTA	104	11,283
	10 20 30 40 50 60 MAVIADPETA QGFRLAGLEG YGASSAEEAQ SLLETLVERG GYALVAVDEA LLPDPERAVE 70 80 90 100 RLMRGRDLPV LLPIAGLKEA FQGHDVEGYM RELVRKTIGF DIKL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"V-type H+-ATPase/synthase from a thermophilic eubacterium, Thermus thermophilus. Subunit structure and operon." Yokoyama K., Ohkuma S., Taguchi H., Yasunaga T., Wakabayashi T., Yoshida M. J. Biol. Chem. 275:13955-13961(2000) [PubMed: 10788522] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Complete genome sequence of Thermus thermophilus HB8." Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T., Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S. Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HB8 / ATCC 27634 / DSM 579.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

D63799 Genomic DNA. Translation: BAA09872.1.
AP008226 Genomic DNA. Translation: BAD71097.1.

RefSeq

YP_144540.1. NC_006461.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2D00	X-ray	2.20	A/B/C/D/E/F	1-104	[»]
3A5C	X-ray	4.51	H/P	1-104	[»]
3A5D	X-ray	4.80	H/P	1-104	[»]

ProteinModelPortal

P74903.

SMR

P74903. Positions 1-104.

ModBase

Search...

Protein-protein interaction databases

STRING

P74903.

Protein family/group databases

TCDB

3.A.2.2.1. H+- or Na+-translocating F-type, V-type and A-type ATPase (F-ATPase) superfamily.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

3169040.

GenomeReviews

Gene locus TTHA1274 in contig AP008226_GR.

KEGG

ttj:TTHA1274.

NMPDR

fig|300852.3.peg.1527.

PATRIC

23957511. VBITheThe93045_1253.

Phylogenomic databases

eggNOG

COG1436.

HOGENOM

HBG449424.

OMA

TIGFDIK.

ProtClustDB

CLSK444670.

Enzyme and pathway databases

BioCyc

TTHE300852:TTHA1274-MONOMER.

Family and domain databases

HAMAP

MF_00312. ATP_synth_F_arch.
[Tree]

InterPro

IPR022944. ATPase_V1-cplx_fsu_bac/arc.
IPR008218. ATPase_V1/A1-cplx_fsu.
[Graphical view]

KO

K02122.

Pfam

PF01990. ATP-synt_F. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

VATF_THET8

Accession

Primary (citable) accession number: P74903
Secondary accession number(s): Q5SIU0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 24, 2001
Last sequence update:	February 1, 1997
Last modified:	January 25, 2012
This is version 79 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program