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P74745 (SPKC_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 100. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Serine/threonine-protein kinase C

EC=2.7.11.1
Gene names
Name:spkC
Ordered Locus Names:slr0599
OrganismSynechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]
Taxonomic identifier1111708 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis

Protein attributes

Sequence length535 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 1 protein kinase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 535535Serine/threonine-protein kinase C
PRO_0000171241

Regions

Domain12 – 277266Protein kinase
Nucleotide binding18 – 269ATP By similarity

Sites

Active site1421Proton acceptor By similarity
Binding site431ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
P74745 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 533CD9FC0E3D23D8

FASTA53558,142
        10         20         30         40         50         60 
MVTPLKLLNN RYRIIETLGR GGFGETFLAQ DTHMPSARKC VIKHLKPVLE NPEIPSWLRE 

        70         80         90        100        110        120 
RFHREAATLE ELGENHPQIP QLYAYFSEGE DFYLVQEWIP GLTLTQAHAQ KGNFSSTAVE 

       130        140        150        160        170        180 
ELLLGILPVL EFIHQRRIIH RDIKPDNIIL READGKPILI DFGIIKETMG TLVNPDGRSA 

       190        200        210        220        230        240 
YSVALGTPGY MASEQAAGRP VFSSDLYSLG LTAIFLLTGK TPQYLTSDSR TGEILWRQGA 

       250        260        270        280        290        300 
PQVSPTLAKV IDQAVRYHPR ERFNSATAMA QTLQGNFSNV PMTKGDRPGN TVANGKTKSN 

       310        320        330        340        350        360 
HQPTAPTLVV GTPYNANDTQ ATKVYTQEFT GYTETQEGSP LMKWVVMPLV VLLVIGGGMA 

       370        380        390        400        410        420 
AGFWVTSQRR NNPPPAVEEP TEETPIPLPS LEPRPNLFET PSPIPTPATP SPEPTPSPSP 

       430        440        450        460        470        480 
SPETTSSPTE DTITPMEPEP SLDEPAPIPE PKPSPSPTIS PQPSPTISIP VTPAPVPKPS 

       490        500        510        520        530 
PSPTPKPTVP PQISPTPQPS NTVPVIPPPE NPSAETEPNL PAPPVGEKPI DPEQN 

« Hide

References

« Hide 'large scale' references
[1]"Biochemical examination of the potential eukaryotic-type protein kinase genes in the complete genome of the unicellular Cyanobacterium synechocystis sp. PCC 6803."
Kamei A., Yuasa T., Geng X., Ikeuchi M.
DNA Res. 9:71-78(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], CHARACTERIZATION.
[2]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. expand/collapse author list , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 6803 / Kazusa.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB046599 Genomic DNA. Translation: BAB17035.1.
BA000022 Genomic DNA. Translation: BAA18865.1.
PIRS76953.
RefSeqNP_443053.1. NC_000911.1.
YP_005653112.1. NC_017277.1.
YP_007452928.1. NC_020286.1.

3D structure databases

ProteinModelPortalP74745.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActP74745. 5 interactions.
STRING1148.slr0599.

Proteomic databases

PaxDbP74745.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA18865; BAA18865; BAA18865.
GeneID951853.
KEGGsyn:slr0599.
syy:SYNGTS_3159.
syz:MYO_131950.
PATRIC23843964. VBISynSp132158_3512.

Phylogenomic databases

eggNOGCOG0515.
KOK08884.
OMAARHAITD.
OrthoDBEOG6BKJ4J.
PhylomeDBP74745.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 2 hits.
PROSITEPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSPKC_SYNY3
AccessionPrimary (citable) accession number: P74745
Entry history
Integrated into UniProtKB/Swiss-Prot: August 14, 2001
Last sequence update: February 1, 1997
Last modified: July 9, 2014
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Synechocystis PCC 6803

Synechocystis (strain PCC 6803): entries and gene names

SIMILARITY comments

Index of protein domains and families