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P74745

- SPKC_SYNY3

UniProt

P74745 - SPKC_SYNY3

Protein

Serine/threonine-protein kinase C

Gene

spkC

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 101 (01 Oct 2014)
      Sequence version 1 (01 Feb 1997)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei43 – 431ATPPROSITE-ProRule annotation
    Active sitei142 – 1421Proton acceptorPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi18 – 269ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. protein serine/threonine kinase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Serine/threonine-protein kinase C (EC:2.7.11.1)
    Gene namesi
    Name:spkC
    Ordered Locus Names:slr0599
    OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
    Taxonomic identifieri1111708 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
    ProteomesiUP000001425: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 535535Serine/threonine-protein kinase CPRO_0000171241Add
    BLAST

    Proteomic databases

    PaxDbiP74745.

    Interactioni

    Protein-protein interaction databases

    IntActiP74745. 5 interactions.
    STRINGi1148.slr0599.

    Structurei

    3D structure databases

    ProteinModelPortaliP74745.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini12 – 277266Protein kinasePROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
    Contains 1 protein kinase domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0515.
    KOiK08884.
    OMAiARHAITD.
    OrthoDBiEOG6BKJ4J.
    PhylomeDBiP74745.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF00069. Pkinase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 2 hits.
    PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P74745-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVTPLKLLNN RYRIIETLGR GGFGETFLAQ DTHMPSARKC VIKHLKPVLE    50
    NPEIPSWLRE RFHREAATLE ELGENHPQIP QLYAYFSEGE DFYLVQEWIP 100
    GLTLTQAHAQ KGNFSSTAVE ELLLGILPVL EFIHQRRIIH RDIKPDNIIL 150
    READGKPILI DFGIIKETMG TLVNPDGRSA YSVALGTPGY MASEQAAGRP 200
    VFSSDLYSLG LTAIFLLTGK TPQYLTSDSR TGEILWRQGA PQVSPTLAKV 250
    IDQAVRYHPR ERFNSATAMA QTLQGNFSNV PMTKGDRPGN TVANGKTKSN 300
    HQPTAPTLVV GTPYNANDTQ ATKVYTQEFT GYTETQEGSP LMKWVVMPLV 350
    VLLVIGGGMA AGFWVTSQRR NNPPPAVEEP TEETPIPLPS LEPRPNLFET 400
    PSPIPTPATP SPEPTPSPSP SPETTSSPTE DTITPMEPEP SLDEPAPIPE 450
    PKPSPSPTIS PQPSPTISIP VTPAPVPKPS PSPTPKPTVP PQISPTPQPS 500
    NTVPVIPPPE NPSAETEPNL PAPPVGEKPI DPEQN 535
    Length:535
    Mass (Da):58,142
    Last modified:February 1, 1997 - v1
    Checksum:i533CD9FC0E3D23D8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB046599 Genomic DNA. Translation: BAB17035.1.
    BA000022 Genomic DNA. Translation: BAA18865.1.
    PIRiS76953.
    RefSeqiNP_443053.1. NC_000911.1.
    YP_005653112.1. NC_017277.1.
    YP_007452928.1. NC_020286.1.

    Genome annotation databases

    EnsemblBacteriaiBAA18865; BAA18865; BAA18865.
    GeneIDi951853.
    KEGGisyn:slr0599.
    syy:SYNGTS_3159.
    syz:MYO_131950.
    PATRICi23843964. VBISynSp132158_3512.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB046599 Genomic DNA. Translation: BAB17035.1 .
    BA000022 Genomic DNA. Translation: BAA18865.1 .
    PIRi S76953.
    RefSeqi NP_443053.1. NC_000911.1.
    YP_005653112.1. NC_017277.1.
    YP_007452928.1. NC_020286.1.

    3D structure databases

    ProteinModelPortali P74745.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi P74745. 5 interactions.
    STRINGi 1148.slr0599.

    Proteomic databases

    PaxDbi P74745.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAA18865 ; BAA18865 ; BAA18865 .
    GeneIDi 951853.
    KEGGi syn:slr0599.
    syy:SYNGTS_3159.
    syz:MYO_131950.
    PATRICi 23843964. VBISynSp132158_3512.

    Phylogenomic databases

    eggNOGi COG0515.
    KOi K08884.
    OMAi ARHAITD.
    OrthoDBi EOG6BKJ4J.
    PhylomeDBi P74745.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 2 hits.
    PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Biochemical examination of the potential eukaryotic-type protein kinase genes in the complete genome of the unicellular Cyanobacterium synechocystis sp. PCC 6803."
      Kamei A., Yuasa T., Geng X., Ikeuchi M.
      DNA Res. 9:71-78(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], CHARACTERIZATION.
    2. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
      Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
      , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
      DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PCC 6803 / Kazusa.

    Entry informationi

    Entry nameiSPKC_SYNY3
    AccessioniPrimary (citable) accession number: P74745
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 14, 2001
    Last sequence update: February 1, 1997
    Last modified: October 1, 2014
    This is version 101 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Synechocystis PCC 6803
      Synechocystis (strain PCC 6803): entries and gene names

    External Data

    Dasty 3