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Protein

Serine/threonine-protein kinase C

Gene

spkC

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei43ATPPROSITE-ProRule annotation1
Active sitei142Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi18 – 26ATPPROSITE-ProRule annotation9

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein kinase C (EC:2.7.11.1)
Gene namesi
Name:spkC
Ordered Locus Names:slr0599
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesMerismopediaceaeSynechocystis
Proteomesi
  • UP000001425 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001712411 – 535Serine/threonine-protein kinase CAdd BLAST535

Proteomic databases

PRIDEiP74745.

Interactioni

Protein-protein interaction databases

IntActiP74745. 5 interactors.

Structurei

3D structure databases

ProteinModelPortaliP74745.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 277Protein kinasePROSITE-ProRule annotationAdd BLAST266

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Phylogenomic databases

InParanoidiP74745.
KOiK08884.
OMAiARHAITD.
PhylomeDBiP74745.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 2 hits.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P74745-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVTPLKLLNN RYRIIETLGR GGFGETFLAQ DTHMPSARKC VIKHLKPVLE
60 70 80 90 100
NPEIPSWLRE RFHREAATLE ELGENHPQIP QLYAYFSEGE DFYLVQEWIP
110 120 130 140 150
GLTLTQAHAQ KGNFSSTAVE ELLLGILPVL EFIHQRRIIH RDIKPDNIIL
160 170 180 190 200
READGKPILI DFGIIKETMG TLVNPDGRSA YSVALGTPGY MASEQAAGRP
210 220 230 240 250
VFSSDLYSLG LTAIFLLTGK TPQYLTSDSR TGEILWRQGA PQVSPTLAKV
260 270 280 290 300
IDQAVRYHPR ERFNSATAMA QTLQGNFSNV PMTKGDRPGN TVANGKTKSN
310 320 330 340 350
HQPTAPTLVV GTPYNANDTQ ATKVYTQEFT GYTETQEGSP LMKWVVMPLV
360 370 380 390 400
VLLVIGGGMA AGFWVTSQRR NNPPPAVEEP TEETPIPLPS LEPRPNLFET
410 420 430 440 450
PSPIPTPATP SPEPTPSPSP SPETTSSPTE DTITPMEPEP SLDEPAPIPE
460 470 480 490 500
PKPSPSPTIS PQPSPTISIP VTPAPVPKPS PSPTPKPTVP PQISPTPQPS
510 520 530
NTVPVIPPPE NPSAETEPNL PAPPVGEKPI DPEQN
Length:535
Mass (Da):58,142
Last modified:February 1, 1997 - v1
Checksum:i533CD9FC0E3D23D8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB046599 Genomic DNA. Translation: BAB17035.1.
BA000022 Genomic DNA. Translation: BAA18865.1.
PIRiS76953.

Genome annotation databases

EnsemblBacteriaiBAA18865; BAA18865; BAA18865.
KEGGisyn:slr0599.
PATRICi23843964. VBISynSp132158_3512.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB046599 Genomic DNA. Translation: BAB17035.1.
BA000022 Genomic DNA. Translation: BAA18865.1.
PIRiS76953.

3D structure databases

ProteinModelPortaliP74745.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP74745. 5 interactors.

Proteomic databases

PRIDEiP74745.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA18865; BAA18865; BAA18865.
KEGGisyn:slr0599.
PATRICi23843964. VBISynSp132158_3512.

Phylogenomic databases

InParanoidiP74745.
KOiK08884.
OMAiARHAITD.
PhylomeDBiP74745.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 2 hits.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSPKC_SYNY3
AccessioniPrimary (citable) accession number: P74745
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 14, 2001
Last sequence update: February 1, 1997
Last modified: November 2, 2016
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.