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P74739 (FUR_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ferric uptake regulation protein
Short name=Ferric uptake regulator
Gene names
Name:fur
Ordered Locus Names:sll0567
OrganismSynechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]
Taxonomic identifier1111708 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Oscillatoriophycideae › Chroococcales › Synechocystis ›

Protein attributes

Sequence length165 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Acts as a global negative controlling element, employing Fe2+ as a cofactor to bind the operator of the repressed genes By similarity.

Subunit structure

Homodimer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the Fur family.

Ontologies

Keywords
   Biological processTranscription
Transcription regulation
   Cellular componentCytoplasm
   LigandDNA-binding
Iron
Metal-binding
Zinc
   Molecular functionRepressor
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtranscription, DNA-dependent

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

sequence-specific DNA binding transcription factor activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 165165Ferric uptake regulation protein
PRO_0000095583

Regions

Region1 – 9191DNA-binding By similarity
Region92 – 16574Dimerization By similarity
Compositional bias93 – 975His-rich

Sites

Metal binding381Zinc By similarity
Metal binding861Zinc By similarity
Metal binding941Iron By similarity
Metal binding961Iron By similarity
Metal binding971Zinc By similarity
Metal binding1001Zinc By similarity
Metal binding1031Zinc By similarity
Metal binding1081Zinc By similarity

Sequences

Sequence LengthMass (Da)Tools
P74739 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 5F1A54D89336BA14

FASTA16519,072
        10         20         30         40         50         60 
MSYTADSLKA ELNARGWRLT PQREKILTIF QNLPEGEHLS AEELHHRLEE EREKISLSTV 

        70         80         90        100        110        120 
YRSVKLMSRM GILRELELAE GHKHYELQQA SPHHHHHVVC VQCNRTIEFK NDSILKQSLK 

       130        140        150        160 
QCEKEGFQLI DCQLTVTTIC PEAIRMGWPS TLPSNWACTR SISLA

« Hide

References

[1]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. expand/collapse author list , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 6803 / Kazusa.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000022 Genomic DNA. Translation: BAA18859.1.
PIRS76947.
RefSeqNP_443047.1. NC_000911.1.
YP_005653106.1. NC_017277.1.
YP_007452922.1. NC_020286.1.

3D structure databases

ProteinModelPortalP74739.
ModBaseSearch...

Protein-protein interaction databases

STRING1148.sll0567.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA18859; BAA18859; BAA18859.
GeneID12255637.
14618614.
952481.
KEGGsyn:sll0567.
syy:SYNGTS_3153.
PATRIC23843952. VBISynSp132158_3506.

Phylogenomic databases

eggNOGCOG0735.
HOGENOMHOG000014143.
KOK03711.
OMAHRYELLS.
ProtClustDBCLSK893830.

Family and domain databases

Gene3D1.10.10.10. 1 hit.
InterProIPR002481. FUR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamPF01475. FUR. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameFUR_SYNY3
AccessionPrimary (citable) accession number: P74739
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: February 1, 1997
Last modified: May 1, 2013
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Synechocystis PCC 6803

Synechocystis (strain PCC 6803): entries and gene names

SIMILARITY comments

Index of protein domains and families

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