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P74739

- FUR_SYNY3

UniProt

P74739 - FUR_SYNY3

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Protein

Ferric uptake regulation protein

Gene

fur

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Acts as a global negative controlling element, employing Fe2+ as a cofactor to bind the operator of the repressed genes.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi38 – 381ZincBy similarity
Metal bindingi86 – 861ZincBy similarity
Metal bindingi94 – 941IronBy similarity
Metal bindingi96 – 961IronBy similarity
Metal bindingi97 – 971ZincBy similarity
Metal bindingi100 – 1001ZincBy similarity
Metal bindingi103 – 1031ZincBy similarity
Metal bindingi108 – 1081ZincBy similarity

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. metal ion binding Source: UniProtKB-KW
  3. sequence-specific DNA binding transcription factor activity Source: InterPro

GO - Biological processi

  1. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Repressor

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Iron, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Ferric uptake regulation protein
Short name:
Ferric uptake regulator
Gene namesi
Name:fur
Ordered Locus Names:sll0567
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
ProteomesiUP000001425: Chromosome

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 165165Ferric uptake regulation proteinPRO_0000095583Add
BLAST

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi1148.sll0567.

Structurei

3D structure databases

ProteinModelPortaliP74739.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni1 – 9191DNA-bindingBy similarityAdd
BLAST
Regioni92 – 16574DimerizationBy similarityAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi93 – 975His-rich

Sequence similaritiesi

Belongs to the Fur family.Curated

Phylogenomic databases

eggNOGiCOG0735.
HOGENOMiHOG000014143.
InParanoidiP74739.
KOiK03711.
OMAiESPGIAS.
OrthoDBiEOG6J48SS.
PhylomeDBiP74739.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiIPR002481. FUR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF01475. FUR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P74739-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSYTADSLKA ELNARGWRLT PQREKILTIF QNLPEGEHLS AEELHHRLEE
60 70 80 90 100
EREKISLSTV YRSVKLMSRM GILRELELAE GHKHYELQQA SPHHHHHVVC
110 120 130 140 150
VQCNRTIEFK NDSILKQSLK QCEKEGFQLI DCQLTVTTIC PEAIRMGWPS
160
TLPSNWACTR SISLA
Length:165
Mass (Da):19,072
Last modified:February 1, 1997 - v1
Checksum:i5F1A54D89336BA14
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA18859.1.
PIRiS76947.
RefSeqiNP_443047.1. NC_000911.1.
YP_005653106.1. NC_017277.1.
YP_007452922.1. NC_020286.1.

Genome annotation databases

EnsemblBacteriaiBAA18859; BAA18859; BAA18859.
GeneIDi952481.
KEGGisyn:sll0567.
PATRICi23843952. VBISynSp132158_3506.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA18859.1 .
PIRi S76947.
RefSeqi NP_443047.1. NC_000911.1.
YP_005653106.1. NC_017277.1.
YP_007452922.1. NC_020286.1.

3D structure databases

ProteinModelPortali P74739.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 1148.sll0567.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAA18859 ; BAA18859 ; BAA18859 .
GeneIDi 952481.
KEGGi syn:sll0567.
PATRICi 23843952. VBISynSp132158_3506.

Phylogenomic databases

eggNOGi COG0735.
HOGENOMi HOG000014143.
InParanoidi P74739.
KOi K03711.
OMAi ESPGIAS.
OrthoDBi EOG6J48SS.
PhylomeDBi P74739.

Family and domain databases

Gene3Di 1.10.10.10. 1 hit.
InterProi IPR002481. FUR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
Pfami PF01475. FUR. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / Kazusa.

Entry informationi

Entry nameiFUR_SYNY3
AccessioniPrimary (citable) accession number: P74739
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: February 1, 1997
Last modified: November 26, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

External Data

Dasty 3