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Protein

Protein RecA

Gene

recA

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi68 – 75ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

DNA recombination

Keywords - Ligandi

ATP-binding, DNA-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Protein RecAUniRule annotation
Alternative name(s):
Recombinase AUniRule annotation
Gene namesi
Name:recAUniRule annotation
Ordered Locus Names:sll0569
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesMerismopediaceaeSynechocystis
Proteomesi
  • UP000001425 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001228771 – 354Protein RecAAdd BLAST354

Proteomic databases

PRIDEiP74737.

Expressioni

Inductioni

Expressed in light grown cells, strongly repressed post-transcriptionally by UV-C light, repressed by H2O2 and SeO4 but not by SeO3 (PubMed:15225304).1 Publication

Interactioni

Protein-protein interaction databases

IntActiP74737. 1 interactor.

Structurei

3D structure databases

ProteinModelPortaliP74737.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RecA family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000264120.
InParanoidiP74737.
KOiK03553.
OMAiTRKGAWY.
PhylomeDBiP74737.

Family and domain databases

CDDicd00983. recA. 1 hit.
Gene3Di3.30.250.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00268. RecA. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR013765. DNA_recomb/repair_RecA.
IPR020584. DNA_recomb/repair_RecA_CS.
IPR027417. P-loop_NTPase.
IPR020588. RecA_ATP-bd.
IPR023400. RecA_C.
IPR020587. RecA_monomer-monomer_interface.
[Graphical view]
PANTHERiPTHR22942:SF1. PTHR22942:SF1. 1 hit.
PfamiPF00154. RecA. 1 hit.
[Graphical view]
PRINTSiPR00142. RECA.
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF54752. SSF54752. 1 hit.
TIGRFAMsiTIGR02012. tigrfam_recA. 1 hit.
PROSITEiPS00321. RECA_1. 1 hit.
PS50162. RECA_2. 1 hit.
PS50163. RECA_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P74737-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASTNISDRE KALNAALAQI ERSFGKGAIM RLGDATQMRV ETISTGALTL
60 70 80 90 100
DLALGGGLPK GRIVEIYGPE SSGKTTLALH AVAATQQAGG VAAFVDAEHA
110 120 130 140 150
LDPVYSKALG VDIDNLLVAQ PDNGESALEI VDQLVRSTAV DIIVVDSVAA
160 170 180 190 200
LVPRAEIEGE MGDTSVGSQA RLMSKAMRKI AGNIGRSGCL VIFLNQLRQK
210 220 230 240 250
IGVTYGSPEV TTGGNALKFY ASVRLDIRRI QTLKKGTEGE YGIRAKVKVA
260 270 280 290 300
KNKVAPPFRI AEFDIIFGQG ISRMGCTIDL AEKCEVITRK GAWYSYNGEN
310 320 330 340 350
IAQGRDNAMK YLEENPEIAA TIDQQVREKL SLVNAVFPVE TEDGAEEQGE

DGDF
Length:354
Mass (Da):37,805
Last modified:February 1, 1997 - v1
Checksum:i67BD15C5162722CD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA18857.1.
PIRiS76945.

Genome annotation databases

EnsemblBacteriaiBAA18857; BAA18857; BAA18857.
KEGGisyn:sll0569.
PATRICi23843948. VBISynSp132158_3504.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA18857.1.
PIRiS76945.

3D structure databases

ProteinModelPortaliP74737.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP74737. 1 interactor.

Proteomic databases

PRIDEiP74737.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA18857; BAA18857; BAA18857.
KEGGisyn:sll0569.
PATRICi23843948. VBISynSp132158_3504.

Phylogenomic databases

HOGENOMiHOG000264120.
InParanoidiP74737.
KOiK03553.
OMAiTRKGAWY.
PhylomeDBiP74737.

Family and domain databases

CDDicd00983. recA. 1 hit.
Gene3Di3.30.250.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00268. RecA. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR013765. DNA_recomb/repair_RecA.
IPR020584. DNA_recomb/repair_RecA_CS.
IPR027417. P-loop_NTPase.
IPR020588. RecA_ATP-bd.
IPR023400. RecA_C.
IPR020587. RecA_monomer-monomer_interface.
[Graphical view]
PANTHERiPTHR22942:SF1. PTHR22942:SF1. 1 hit.
PfamiPF00154. RecA. 1 hit.
[Graphical view]
PRINTSiPR00142. RECA.
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF54752. SSF54752. 1 hit.
TIGRFAMsiTIGR02012. tigrfam_recA. 1 hit.
PROSITEiPS00321. RECA_1. 1 hit.
PS50162. RECA_2. 1 hit.
PS50163. RECA_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRECA_SYNY3
AccessioniPrimary (citable) accession number: P74737
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: November 2, 2016
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

This bacterium is considerably more resistant to UV and gamma irradiation than E.coli; the E.coli-like SOS regulon model is not an appropriate model for DNA repair in this cyanobacterium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.