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P74707 (RF1_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 95. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Peptide chain release factor 1

Short name=RF-1
Gene names
Name:prfA
Ordered Locus Names:sll1110
OrganismSynechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]
Taxonomic identifier1111708 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis

Protein attributes

Sequence length365 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA By similarity. HAMAP-Rule MF_00093

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00093.

Post-translational modification

Methylated by PrmC. Methylation increases the termination efficiency of RF1 By similarity. HAMAP-Rule MF_00093

Sequence similarities

Belongs to the prokaryotic/mitochondrial release factor family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   PTMMethylation
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functiontranslation release factor activity, codon specific

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 365365Peptide chain release factor 1 HAMAP-Rule MF_00093
PRO_0000177760

Amino acid modifications

Modified residue2391N5-methylglutamine By similarity

Sequences

Sequence LengthMass (Da)Tools
P74707 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: D565402A35E27EAC

FASTA36541,126
        10         20         30         40         50         60 
MAETYLLDKL ASVEQTYQEL TRMLADPDIA TNPDELQRVA KARSSLEETV DTYETWKRSQ 

        70         80         90        100        110        120 
EDLKGARQIV KESGNDPEMR EMAQLEVEEL ENAIGELEKR LTILLLPKDP NDEKNIMLEI 

       130        140        150        160        170        180 
RAGTGGDEAS IWAGDLVRMY TRYAESQGWK VSLLSESLAD MGGFKEAILE VKGDRVYSQL 

       190        200        210        220        230        240 
KFEAGVHRVQ RVPVTEAGGR VHTSTATVAI MPEVDDVEVK IDPKDIEMST ARSGGAGGQN 

       250        260        270        280        290        300 
VNKVETAVDL FHKPTGIRIF CTEERSQLQN RERAMQILRA KLYDMMLQEQ NDAISSNRRS 

       310        320        330        340        350        360 
QVGTGSRSEK IRTYNYKDNR VTDHRLGRNF DLNTALEGEI HTIIESCISQ DQQERLAELA 


EATNN 

« Hide

References

[1]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. expand/collapse author list , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 6803 / Kazusa.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000022 Genomic DNA. Translation: BAA18826.1.
PIRS76914.
RefSeqNP_443014.1. NC_000911.1.
YP_005653073.1. NC_017277.1.
YP_007452889.1. NC_020286.1.

3D structure databases

ProteinModelPortalP74707.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActP74707. 2 interactions.
STRING1148.sll1110.

Proteomic databases

PaxDbP74707.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA18826; BAA18826; BAA18826.
GeneID951907.
KEGGsyn:sll1110.
syy:SYNGTS_3120.
syz:MYO_131560.
PATRIC23843878. VBISynSp132158_3469.

Phylogenomic databases

eggNOGCOG0216.
HOGENOMHOG000074815.
KOK02835.
OMAKDSRVTD.
OrthoDBEOG6TN48J.
PhylomeDBP74707.

Family and domain databases

Gene3D3.30.160.20. 1 hit.
HAMAPMF_00093. Rel_fac_1.
InterProIPR014720. dsRNA-bd_dom.
IPR005139. PCRF.
IPR000352. Pep_chain_release_fac_I_II.
IPR004373. PrfA.
[Graphical view]
PfamPF03462. PCRF. 1 hit.
PF00472. RF-1. 1 hit.
[Graphical view]
SMARTSM00937. PCRF. 1 hit.
[Graphical view]
TIGRFAMsTIGR00019. prfA. 1 hit.
PROSITEPS00745. RF_PROK_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRF1_SYNY3
AccessionPrimary (citable) accession number: P74707
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: July 9, 2014
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Synechocystis PCC 6803

Synechocystis (strain PCC 6803): entries and gene names

SIMILARITY comments

Index of protein domains and families