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Protein

Peptide chain release factor 1

Gene

prfA

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.By similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Protein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Peptide chain release factor 1
Short name:
RF-1
Gene namesi
Name:prfA
Ordered Locus Names:sll1110
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesMerismopediaceaeSynechocystis
Proteomesi
  • UP000001425 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001777601 – 365Peptide chain release factor 1Add BLAST365

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei239N5-methylglutamineBy similarity1

Post-translational modificationi

Methylated by PrmC. Methylation increases the termination efficiency of RF1 (By similarity).By similarity

Keywords - PTMi

Methylation

Interactioni

Protein-protein interaction databases

IntActiP74707. 2 interactors.

Structurei

3D structure databases

ProteinModelPortaliP74707.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000074815.
InParanoidiP74707.
KOiK02835.
OMAiGVWAHLK.
PhylomeDBiP74707.

Family and domain databases

Gene3Di3.30.160.20. 1 hit.
HAMAPiMF_00093. Rel_fac_1. 1 hit.
InterProiIPR014720. dsRBD_dom.
IPR005139. PCRF.
IPR000352. Pep_chain_release_fac_I_II.
IPR004373. PrfA.
[Graphical view]
PfamiPF03462. PCRF. 1 hit.
PF00472. RF-1. 1 hit.
[Graphical view]
SMARTiSM00937. PCRF. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00019. prfA. 1 hit.
PROSITEiPS00745. RF_PROK_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P74707-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAETYLLDKL ASVEQTYQEL TRMLADPDIA TNPDELQRVA KARSSLEETV
60 70 80 90 100
DTYETWKRSQ EDLKGARQIV KESGNDPEMR EMAQLEVEEL ENAIGELEKR
110 120 130 140 150
LTILLLPKDP NDEKNIMLEI RAGTGGDEAS IWAGDLVRMY TRYAESQGWK
160 170 180 190 200
VSLLSESLAD MGGFKEAILE VKGDRVYSQL KFEAGVHRVQ RVPVTEAGGR
210 220 230 240 250
VHTSTATVAI MPEVDDVEVK IDPKDIEMST ARSGGAGGQN VNKVETAVDL
260 270 280 290 300
FHKPTGIRIF CTEERSQLQN RERAMQILRA KLYDMMLQEQ NDAISSNRRS
310 320 330 340 350
QVGTGSRSEK IRTYNYKDNR VTDHRLGRNF DLNTALEGEI HTIIESCISQ
360
DQQERLAELA EATNN
Length:365
Mass (Da):41,126
Last modified:February 1, 1997 - v1
Checksum:iD565402A35E27EAC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA18826.1.
PIRiS76914.

Genome annotation databases

EnsemblBacteriaiBAA18826; BAA18826; BAA18826.
KEGGisyn:sll1110.
PATRICi23843878. VBISynSp132158_3469.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA18826.1.
PIRiS76914.

3D structure databases

ProteinModelPortaliP74707.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP74707. 2 interactors.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA18826; BAA18826; BAA18826.
KEGGisyn:sll1110.
PATRICi23843878. VBISynSp132158_3469.

Phylogenomic databases

HOGENOMiHOG000074815.
InParanoidiP74707.
KOiK02835.
OMAiGVWAHLK.
PhylomeDBiP74707.

Family and domain databases

Gene3Di3.30.160.20. 1 hit.
HAMAPiMF_00093. Rel_fac_1. 1 hit.
InterProiIPR014720. dsRBD_dom.
IPR005139. PCRF.
IPR000352. Pep_chain_release_fac_I_II.
IPR004373. PrfA.
[Graphical view]
PfamiPF03462. PCRF. 1 hit.
PF00472. RF-1. 1 hit.
[Graphical view]
SMARTiSM00937. PCRF. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00019. prfA. 1 hit.
PROSITEiPS00745. RF_PROK_I. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRF1_SYNY3
AccessioniPrimary (citable) accession number: P74707
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: November 2, 2016
This is version 109 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.