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Protein

Circadian clock protein KaiB

Gene

kaiB

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC.UniRule annotation

GO - Biological processi

  • circadian rhythm Source: UniProtKB
Complete GO annotation...

Keywords - Biological processi

Biological rhythms

Names & Taxonomyi

Protein namesi
Recommended name:
Circadian clock protein KaiBUniRule annotation
Gene namesi
Name:kaiBUniRule annotation
Ordered Locus Names:slr0757
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesMerismopediaceaeSynechocystis
Proteomesi
  • UP000001425 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002177711 – 105Circadian clock protein KaiBAdd BLAST105

Proteomic databases

PRIDEiP74645.

Interactioni

Subunit structurei

Homodimer. Component of the KaiABC complex, at least composed of a KaiC homohexamer, a KaiB dimer and two KaiA dimers. The KaiABC complex also interacts with SasA.UniRule annotation

Binary interactionsi

WithEntry#Exp.IntActNotes
itself2EBI-629476,EBI-629476

Structurei

Secondary structure

1105
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi6 – 16Combined sources11
Helixi19 – 36Combined sources18
Beta strandi39 – 46Combined sources8
Turni47 – 49Combined sources3
Beta strandi58 – 60Combined sources3
Helixi62 – 65Combined sources4
Helixi66 – 68Combined sources3
Helixi71 – 82Combined sources12
Beta strandi87 – 97Combined sources11

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1WWJX-ray1.90A/B/C/D1-105[»]
ProteinModelPortaliP74645.
SMRiP74645.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP74645.

Family & Domainsi

Sequence similaritiesi

Belongs to the KaiB family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000230415.
InParanoidiP74645.
OMAiDICERHL.
PhylomeDBiP74645.

Family and domain databases

CDDicd02978. KaiB_like. 1 hit.
Gene3Di3.40.30.10. 1 hit.
HAMAPiMF_01835. KaiB. 1 hit.
InterProiIPR013474. Circ_KaiB.
IPR011649. KaiB_domain.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF07689. KaiB. 1 hit.
[Graphical view]
SMARTiSM01248. KaiB. 1 hit.
[Graphical view]
SUPFAMiSSF52833. SSF52833. 1 hit.
TIGRFAMsiTIGR02654. circ_KaiB. 1 hit.

Sequencei

Sequence statusi: Complete.

P74645-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSPFKKTYVL KLYVAGNTPN SVRALKMLKN ILEQEFQGVY ALKVIDVLKN
60 70 80 90 100
PQLAEEDKIL ATPTLAKILP PPVRKIIGDL SDREKVLIGL DLLYDEIRER

EAEDQ
Length:105
Mass (Da):11,935
Last modified:February 1, 1997 - v1
Checksum:i0A0C8618CF01B23D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA18761.1.
PIRiS76849.

Genome annotation databases

EnsemblBacteriaiBAA18761; BAA18761; BAA18761.
KEGGisyn:slr0757.
PATRICi23843720. VBISynSp132158_3390.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA18761.1.
PIRiS76849.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1WWJX-ray1.90A/B/C/D1-105[»]
ProteinModelPortaliP74645.
SMRiP74645.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiP74645.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA18761; BAA18761; BAA18761.
KEGGisyn:slr0757.
PATRICi23843720. VBISynSp132158_3390.

Phylogenomic databases

HOGENOMiHOG000230415.
InParanoidiP74645.
OMAiDICERHL.
PhylomeDBiP74645.

Miscellaneous databases

EvolutionaryTraceiP74645.

Family and domain databases

CDDicd02978. KaiB_like. 1 hit.
Gene3Di3.40.30.10. 1 hit.
HAMAPiMF_01835. KaiB. 1 hit.
InterProiIPR013474. Circ_KaiB.
IPR011649. KaiB_domain.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF07689. KaiB. 1 hit.
[Graphical view]
SMARTiSM01248. KaiB. 1 hit.
[Graphical view]
SUPFAMiSSF52833. SSF52833. 1 hit.
TIGRFAMsiTIGR02654. circ_KaiB. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiKAIB_SYNY3
AccessioniPrimary (citable) accession number: P74645
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: February 1, 1997
Last modified: November 2, 2016
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.