Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Biosynthetic arginine decarboxylase 1

Gene

speA1

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the biosynthesis of agmatine from arginine.By similarity

Catalytic activityi

L-arginine = agmatine + CO2.

Cofactori

Protein has several cofactor binding sites:

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDecarboxylase, Lyase
Biological processPolyamine biosynthesis, Spermidine biosynthesis
LigandMagnesium, Metal-binding, Pyridoxal phosphate

Enzyme and pathway databases

BRENDAi4.1.1.19 382

Names & Taxonomyi

Protein namesi
Recommended name:
Biosynthetic arginine decarboxylase 1 (EC:4.1.1.19)
Short name:
ADC 1
Gene namesi
Name:speA1
Synonyms:speA
Ordered Locus Names:slr0662
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesMerismopediaceaeSynechocystis
Proteomesi
  • UP000001425 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001499811 – 695Biosynthetic arginine decarboxylase 1Add BLAST695

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei141N6-(pyridoxal phosphate)lysineBy similarity1

Proteomic databases

PaxDbiP74576
PRIDEiP74576

Interactioni

Protein-protein interaction databases

IntActiP74576, 2 interactors
STRINGi1148.SYNGTS_2979

Structurei

3D structure databases

ProteinModelPortaliP74576
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni332 – 342Substrate-bindingSequence analysisAdd BLAST11

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000029191
InParanoidiP74576
KOiK01585
OMAiLFPIMPI
PhylomeDBiP74576

Family and domain databases

CDDicd06830 PLPDE_III_ADC, 1 hit
Gene3Di2.40.37.10, 3 hits
3.20.20.10, 1 hit
HAMAPiMF_01417 SpeA, 1 hit
InterProiView protein in InterPro
IPR009006 Ala_racemase/Decarboxylase_C
IPR002985 Arg_decrbxlase
IPR022657 De-COase2_CS
IPR022644 De-COase2_N
IPR022653 De-COase2_pyr-phos_BS
IPR000183 Orn/DAP/Arg_de-COase
IPR029066 PLP-binding_barrel
PANTHERiPTHR43295 PTHR43295, 1 hit
PfamiView protein in Pfam
PF02784 Orn_Arg_deC_N, 1 hit
PIRSFiPIRSF001336 Arg_decrbxlase, 1 hit
PRINTSiPR01180 ARGDCRBXLASE
PR01179 ODADCRBXLASE
SUPFAMiSSF50621 SSF50621, 1 hit
SSF51419 SSF51419, 1 hit
TIGRFAMsiTIGR01273 speA, 1 hit
PROSITEiView protein in PROSITE
PS00878 ODR_DC_2_1, 1 hit
PS00879 ODR_DC_2_2, 1 hit

Sequencei

Sequence statusi: Complete.

P74576-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEGQSIELEL SVMAMPELID STEAGHTAGV KTDSNPQAIA QDRRWTIDDS
60 70 80 90 100
ENLYRITGWG EPYFSINAAG HVTVSPQADH GGALDLYELV KGLRQRNIGL
110 120 130 140 150
PLLLRFSDIL ADRINRLNAA FARGIARYRY PNTYRGVYPI KCNQHRHIVE
160 170 180 190 200
SLVRYGTPYN FGLEAGSKPE LMIALAMLQP QENPEPDQQN QPLLICNGYK
210 220 230 240 250
DREYIETALL ARRLGHRPII VVEQVAEVAL AIEISSNLGI KPILGVRAKL
260 270 280 290 300
STQGMGRWGI STGDRAKFGL TIPEMLTAIE QLRRADMLDS LQLLHFHIGS
310 320 330 340 350
QISSISVIKE AMTEASQIFV QLAKLGANMR YLDVGGGLGV DYDGSKTNFY
360 370 380 390 400
ASKNYNIQNY VNDVISAVQD ACVAAEVPCP VLISESGRAI ASHQSVLIFD
410 420 430 440 450
VVATNDINPP LPKVKGKDHA ILRNLMETWE TITVDNYQEA YHDVEQFKTE
460 470 480 490 500
AISLFNFGYL GLKERAKAEE LYWACCRKIL QICRQQEYVP DDLENLEVNL
510 520 530 540 550
ASIYYANMSV FQSAPDSWAI DQLFPIMPIH RLDEEPTQRG ILADITCDSD
560 570 580 590 600
GKIDQFIDLR DVKSVLELHP LIEVHQPGTP PRVEPYYLGM FLVGAYQEIM
610 620 630 640 650
GNLHNLFGDI NVVHIQMNPK GYQIEHLVRG DTIAEVLGYV QYDPEDLLEN
660 670 680 690
MRRYCEQAME DKRMSLEEAQ LLLENYERSL LQYTYLKPTS GIHTS
Length:695
Mass (Da):78,239
Last modified:February 1, 1997 - v1
Checksum:iE90EB699D666320D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA Translation: BAA18683.1
PIRiS76771

Genome annotation databases

EnsemblBacteriaiBAA18683; BAA18683; BAA18683
KEGGisyn:slr0662

Similar proteinsi

Entry informationi

Entry nameiSPEA1_SYNY3
AccessioniPrimary (citable) accession number: P74576
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 14, 2001
Last sequence update: February 1, 1997
Last modified: February 28, 2018
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health