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P74507

- GPMI_SYNY3

UniProt

P74507 - GPMI_SYNY3

Protein

2,3-bisphosphoglycerate-independent phosphoglycerate mutase

Gene

gpmI

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 102 (01 Oct 2014)
      Sequence version 1 (01 Feb 1997)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.By similarity

    Catalytic activityi

    2-phospho-D-glycerate = 3-phospho-D-glycerate.

    Cofactori

    Binds 2 manganese ions per subunit.By similarity

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi15 – 151Manganese 2By similarity
    Active sitei65 – 651Phosphoserine intermediateBy similarity
    Metal bindingi65 – 651Manganese 2By similarity
    Metal bindingi398 – 3981Manganese 1By similarity
    Metal bindingi402 – 4021Manganese 1By similarity
    Metal bindingi439 – 4391Manganese 2By similarity
    Metal bindingi440 – 4401Manganese 2By similarity
    Metal bindingi457 – 4571Manganese 1By similarity

    GO - Molecular functioni

    1. 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity Source: UniProtKB-HAMAP
    2. manganese ion binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glucose catabolic process Source: InterPro
    2. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    Manganese, Metal-binding

    Enzyme and pathway databases

    UniPathwayiUPA00109; UER00186.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC:5.4.2.12)
    Short name:
    BPG-independent PGAM
    Short name:
    Phosphoglyceromutase
    Short name:
    iPGM
    Gene namesi
    Name:gpmI
    Synonyms:pgm
    Ordered Locus Names:slr1945
    OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
    Taxonomic identifieri1111708 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
    ProteomesiUP000001425: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 5325322,3-bisphosphoglycerate-independent phosphoglycerate mutasePRO_0000212222Add
    BLAST

    Proteomic databases

    PaxDbiP74507.

    Interactioni

    Subunit structurei

    Monomer.By similarity

    Protein-protein interaction databases

    IntActiP74507. 1 interaction.
    STRINGi1148.slr1945.

    Structurei

    3D structure databases

    ProteinModelPortaliP74507.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0696.
    HOGENOMiHOG000223664.
    KOiK15633.
    OMAiKNAVFHA.
    OrthoDBiEOG6HJ22X.
    PhylomeDBiP74507.

    Family and domain databases

    Gene3Di3.40.1450.10. 1 hit.
    3.40.720.10. 2 hits.
    HAMAPiMF_01038. GpmI.
    InterProiIPR017849. Alkaline_Pase-like_a/b/a.
    IPR017850. Alkaline_phosphatase_core.
    IPR011258. BPG-indep_PGM_N.
    IPR006124. Metalloenzyme.
    IPR005995. Pgm_bpd_ind.
    [Graphical view]
    PfamiPF06415. iPGM_N. 1 hit.
    PF01676. Metalloenzyme. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001492. IPGAM. 1 hit.
    SUPFAMiSSF53649. SSF53649. 2 hits.
    SSF64158. SSF64158. 1 hit.
    TIGRFAMsiTIGR01307. pgm_bpd_ind. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P74507-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAEAPIAPVV LVILDGWGYR PDTRANAIAQ ANTPIMDSLI AAYPNTLVNT    50
    SGKDVGLPKG QMGNSEVGHL NLGAGRVVPQ ELVRISDAIE DGTFFDNQAL 100
    IEVCQRVRDR RGKLHLIGLC SDGGVHSHID HLLGLIDLAK LQGISQLCIH 150
    AITDGRDTPT NEGAHFVQQI QAHLEKIGLG RIVSVSGRYY ALDRDRRWDR 200
    VEKAYRVMTE DGVGDGRSAA QVIKDYYASD ITDEFIPPTR IGAGAIASGD 250
    GVIFYNFRPD RARQLCYALV NPSFDGFPRE RIQPLDFVTF TQYDPALPVV 300
    VAFEPQNLNN ILGEIISRQG MKQFRTAETE KYPHVTYFFN GGLEQPFAGE 350
    DRELIQSPMV STYDKAPQMS AKAVTDAVCR AMEKGIYSLV VVNYANPDMV 400
    GHTGKLKEAI QAIETVDLNL GRLLASAAKV GGTVLITADH GNAEYMSDES 450
    GNPWTAHTTN PVPFILVEGE GRKIPGHGGE VKLREGGKLA DIAPTILDIL 500
    QLPVPAEMTG KTLIDQPLVE IKANRTPVNL SR 532
    Length:532
    Mass (Da):57,982
    Last modified:February 1, 1997 - v1
    Checksum:i936D8E4E5256C6C0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000022 Genomic DNA. Translation: BAA18611.1.
    PIRiS76482.
    RefSeqiNP_441933.1. NC_000911.1.
    YP_005651993.1. NC_017277.1.
    YP_007451813.1. NC_020286.1.

    Genome annotation databases

    EnsemblBacteriaiBAA18611; BAA18611; BAA18611.
    GeneIDi955019.
    KEGGisyn:slr1945.
    syy:SYNGTS_2040.
    syz:MYO_120590.
    PATRICi23841414. VBISynSp132158_2256.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000022 Genomic DNA. Translation: BAA18611.1 .
    PIRi S76482.
    RefSeqi NP_441933.1. NC_000911.1.
    YP_005651993.1. NC_017277.1.
    YP_007451813.1. NC_020286.1.

    3D structure databases

    ProteinModelPortali P74507.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi P74507. 1 interaction.
    STRINGi 1148.slr1945.

    Proteomic databases

    PaxDbi P74507.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAA18611 ; BAA18611 ; BAA18611 .
    GeneIDi 955019.
    KEGGi syn:slr1945.
    syy:SYNGTS_2040.
    syz:MYO_120590.
    PATRICi 23841414. VBISynSp132158_2256.

    Phylogenomic databases

    eggNOGi COG0696.
    HOGENOMi HOG000223664.
    KOi K15633.
    OMAi KNAVFHA.
    OrthoDBi EOG6HJ22X.
    PhylomeDBi P74507.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00186 .

    Family and domain databases

    Gene3Di 3.40.1450.10. 1 hit.
    3.40.720.10. 2 hits.
    HAMAPi MF_01038. GpmI.
    InterProi IPR017849. Alkaline_Pase-like_a/b/a.
    IPR017850. Alkaline_phosphatase_core.
    IPR011258. BPG-indep_PGM_N.
    IPR006124. Metalloenzyme.
    IPR005995. Pgm_bpd_ind.
    [Graphical view ]
    Pfami PF06415. iPGM_N. 1 hit.
    PF01676. Metalloenzyme. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001492. IPGAM. 1 hit.
    SUPFAMi SSF53649. SSF53649. 2 hits.
    SSF64158. SSF64158. 1 hit.
    TIGRFAMsi TIGR01307. pgm_bpd_ind. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
      Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
      , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
      DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: PCC 6803 / Kazusa.

    Entry informationi

    Entry nameiGPMI_SYNY3
    AccessioniPrimary (citable) accession number: P74507
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 15, 1998
    Last sequence update: February 1, 1997
    Last modified: October 1, 2014
    This is version 102 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families
    3. Synechocystis PCC 6803
      Synechocystis (strain PCC 6803): entries and gene names

    External Data

    Dasty 3