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P74507 (GPMI_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 98. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
2,3-bisphosphoglycerate-independent phosphoglycerate mutase

Short name=BPG-independent PGAM
Short name=Phosphoglyceromutase
Short name=iPGM
EC=5.4.2.12
Gene names
Name:gpmI
Synonyms:pgm
Ordered Locus Names:slr1945
OrganismSynechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]
Taxonomic identifier1111708 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis

Protein attributes

Sequence length532 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP-Rule MF_01038

Catalytic activity

2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP-Rule MF_01038

Cofactor

Binds 2 manganese ions per subunit By similarity. HAMAP-Rule MF_01038

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP-Rule MF_01038

Subunit structure

Monomer By similarity. HAMAP-Rule MF_01038

Sequence similarities

Belongs to the BPG-independent phosphoglycerate mutase family.

Ontologies

Keywords
   Biological processGlycolysis
   LigandManganese
Metal-binding
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: InterPro

   Molecular_function2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

manganese ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 5325322,3-bisphosphoglycerate-independent phosphoglycerate mutase HAMAP-Rule MF_01038
PRO_0000212222

Sites

Active site651Phosphoserine intermediate By similarity
Metal binding151Manganese 2 By similarity
Metal binding651Manganese 2 By similarity
Metal binding3981Manganese 1 By similarity
Metal binding4021Manganese 1 By similarity
Metal binding4391Manganese 2 By similarity
Metal binding4401Manganese 2 By similarity
Metal binding4571Manganese 1 By similarity

Sequences

Sequence LengthMass (Da)Tools
P74507 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 936D8E4E5256C6C0

FASTA53257,982
        10         20         30         40         50         60 
MAEAPIAPVV LVILDGWGYR PDTRANAIAQ ANTPIMDSLI AAYPNTLVNT SGKDVGLPKG 

        70         80         90        100        110        120 
QMGNSEVGHL NLGAGRVVPQ ELVRISDAIE DGTFFDNQAL IEVCQRVRDR RGKLHLIGLC 

       130        140        150        160        170        180 
SDGGVHSHID HLLGLIDLAK LQGISQLCIH AITDGRDTPT NEGAHFVQQI QAHLEKIGLG 

       190        200        210        220        230        240 
RIVSVSGRYY ALDRDRRWDR VEKAYRVMTE DGVGDGRSAA QVIKDYYASD ITDEFIPPTR 

       250        260        270        280        290        300 
IGAGAIASGD GVIFYNFRPD RARQLCYALV NPSFDGFPRE RIQPLDFVTF TQYDPALPVV 

       310        320        330        340        350        360 
VAFEPQNLNN ILGEIISRQG MKQFRTAETE KYPHVTYFFN GGLEQPFAGE DRELIQSPMV 

       370        380        390        400        410        420 
STYDKAPQMS AKAVTDAVCR AMEKGIYSLV VVNYANPDMV GHTGKLKEAI QAIETVDLNL 

       430        440        450        460        470        480 
GRLLASAAKV GGTVLITADH GNAEYMSDES GNPWTAHTTN PVPFILVEGE GRKIPGHGGE 

       490        500        510        520        530 
VKLREGGKLA DIAPTILDIL QLPVPAEMTG KTLIDQPLVE IKANRTPVNL SR 

« Hide

References

[1]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. expand/collapse author list , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 6803 / Kazusa.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000022 Genomic DNA. Translation: BAA18611.1.
PIRS76482.
RefSeqNP_441933.1. NC_000911.1.
YP_005651993.1. NC_017277.1.
YP_007451813.1. NC_020286.1.

3D structure databases

ProteinModelPortalP74507.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActP74507. 1 interaction.
STRING1148.slr1945.

Proteomic databases

PaxDbP74507.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA18611; BAA18611; BAA18611.
GeneID12254653.
14617481.
955019.
KEGGsyn:slr1945.
syy:SYNGTS_2040.
syz:MYO_120590.
PATRIC23841414. VBISynSp132158_2256.

Phylogenomic databases

eggNOGCOG0696.
HOGENOMHOG000223664.
KOK15633.
OMAGVHSHIE.
OrthoDBEOG6HJ22X.
PhylomeDBP74507.
ProtClustDBPRK05434.

Enzyme and pathway databases

UniPathwayUPA00109; UER00186.

Family and domain databases

Gene3D3.40.1450.10. 1 hit.
3.40.720.10. 2 hits.
HAMAPMF_01038. GpmI.
InterProIPR017849. Alkaline_Pase-like_a/b/a.
IPR017850. Alkaline_phosphatase_core.
IPR011258. BPG-indep_PGM_N.
IPR006124. Metalloenzyme.
IPR005995. Pgm_bpd_ind.
[Graphical view]
PfamPF06415. iPGM_N. 1 hit.
PF01676. Metalloenzyme. 1 hit.
[Graphical view]
PIRSFPIRSF001492. IPGAM. 1 hit.
SUPFAMSSF53649. SSF53649. 2 hits.
SSF64158. SSF64158. 1 hit.
TIGRFAMsTIGR01307. pgm_bpd_ind. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGPMI_SYNY3
AccessionPrimary (citable) accession number: P74507
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: February 1, 1997
Last modified: April 16, 2014
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Synechocystis PCC 6803

Synechocystis (strain PCC 6803): entries and gene names

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways