P74435 (TRPF_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase
Short name=PRAI
EC=5.3.1.24

Gene names

Name:	trpF
Ordered Locus Names:	sll0356

Organism

Synechocystis sp. (strain PCC 6803 / Kazusa)

Taxonomic identifier

1111708 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechocystis

Protein attributes

Sequence length	218 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP MF_00135
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP MF_00135
Sequence similarities	Belongs to the TrpF family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis
Molecular function	Isomerase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	tryptophan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	phosphoribosylanthranilate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 218	218	N-(5'-phosphoribosyl)anthranilate isomerase HAMAP MF_00135		PRO_0000154389

Sequences

	Sequence		Length	Mass (Da)
	P74435 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 37D6035030C55A4F	FASTA	218	23,881
	10 20 30 40 50 60 MAMEVKICGL RHPAQAQAIA ALGFTTLGFI CVEASSRYVS SREIELVLQS LTAHNKRSAI 70 80 90 100 110 120 GVFANVSLPK LGEFLAQTSL NGIQLHGDES PDFCRQVKQA FPQHRLIKAL RLRRSADLER 130 140 150 160 170 180 AEAYYNAVDV LLLDAYHPEQ LGGTGQTLPW QKLQQFRPPL PWWLAGGLTP SNVQEALNLL 190 200 210 QPDGIDLSSG VEQGPADKDV AKVAQLRAQL DALAILQH

References

[1]

"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed: 8905231] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27184 / PCC 6803 / N-1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000022 Genomic DNA. Translation: BAA18536.1.
PIR	S76407.
RefSeq	NP_441858.1. NC_000911.1.
3D structure databases
ProteinModelPortal	P74435.
ModBase	Search...
Protein-protein interaction databases
STRING	P74435.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	954833.
GenomeReviews	Gene locus sll0356 in contig BA000022_GR.
KEGG	syn:sll0356.
NMPDR	fig|1148.1.peg.1959.
PATRIC	23841238. VBISynSp132158_2169.
Phylogenomic databases
eggNOG	COG0135.
HOGENOM	HBG554803.
OMA	TGEAFDW.
PhylomeDB	P74435.
ProtClustDB	PRK01222.
Enzyme and pathway databases
BioCyc	SSP1148:SLL0356-MONOMER.
Family and domain databases
HAMAP	MF_00135. PRAI. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR001240. PRAI. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01817.
Pfam	PF00697. PRAI. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

TRPF_SYNY3

Accession

Primary (citable) accession number: P74435

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	February 1, 1997
Last modified:	January 25, 2012
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program