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P74421

- PGK_SYNY3

UniProt

P74421 - PGK_SYNY3

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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei40 – 401SubstrateBy similarity
Binding sitei122 – 1221SubstrateBy similarity
Binding sitei155 – 1551SubstrateBy similarity
Binding sitei206 – 2061ATPBy similarity
Binding sitei297 – 2971ATP; via carbonyl oxygenBy similarity
Binding sitei328 – 3281ATPBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi357 – 3604ATPBy similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:pgk
Ordered Locus Names:slr0394
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
ProteomesiUP000001425: Chromosome

Subcellular locationi

Cytoplasm Curated

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 401401Phosphoglycerate kinasePRO_0000146024Add
BLAST

Proteomic databases

PaxDbiP74421.

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

IntActiP74421. 5 interactions.
STRINGi1148.slr0394.

Structurei

3D structure databases

ProteinModelPortaliP74421.
SMRiP74421. Positions 10-401.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni25 – 273Substrate bindingBy similarity
Regioni63 – 664Substrate bindingBy similarity

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.Curated

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227107.
InParanoidiP74421.
OMAiFPVDYVT.
PhylomeDBiP74421.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P74421-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLSKQSIANL TEADLAGKRV FVRVDFNVPL DNGSITDDTR IRAALPTIKD
60 70 80 90 100
LLSKGAKVIL GSHFGRPKGK VVDSMRLTPV GDRLGELLGQ PVVKCDDCIG
110 120 130 140 150
AEVTAKIASL PNGGVALLEN LRFHAGEEGN DAEFAKALAA NADLYVNDAF
160 170 180 190 200
GTAHRAHAST EGVTHFLSPN VAGYLIEKEL QFLQGAIEAP KRPLVAIVGG
210 220 230 240 250
SKVSSKIGVI ETLLDKCDKL IIGGGMIFTF YKAQGLNTGK SLVEEDKLDL
260 270 280 290 300
AKSLMAKAKE KGVEFLLPTD VVVADNFAPD ANAQTVGVDA IPDGWMGLDI
310 320 330 340 350
GPDSVKTFQD ALAGCGTVIW NGPMGVFEFD KFAVGTEAIA CSLAELTASG
360 370 380 390 400
TVTIIGGGDS VAAVEKVGVA EKMSHISTGG GASLELLEGK VLPGIAALDD

R
Length:401
Mass (Da):41,784
Last modified:November 1, 1997 - v2
Checksum:i74905FDBBCF81B7D
GO

Sequence cautioni

The sequence BAA18521.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA18521.1. Different initiation.
PIRiS76392.
RefSeqiYP_007451724.1. NC_020286.1.

Genome annotation databases

EnsemblBacteriaiBAA18521; BAA18521; BAA18521.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000022 Genomic DNA. Translation: BAA18521.1 . Different initiation.
PIRi S76392.
RefSeqi YP_007451724.1. NC_020286.1.

3D structure databases

ProteinModelPortali P74421.
SMRi P74421. Positions 10-401.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi P74421. 5 interactions.
STRINGi 1148.slr0394.

Proteomic databases

PaxDbi P74421.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAA18521 ; BAA18521 ; BAA18521 .

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227107.
InParanoidi P74421.
OMAi FPVDYVT.
PhylomeDBi P74421.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / Kazusa.

Entry informationi

Entry nameiPGK_SYNY3
AccessioniPrimary (citable) accession number: P74421
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: November 26, 2014
This is version 89 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families
  3. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

External Data

Dasty 3