ID   P74400_SYNY3            Unreviewed;      1578 AA.
AC   P74400;
DT   01-FEB-1997, integrated into UniProtKB/TrEMBL.
DT   01-FEB-1997, sequence version 1.
DT   27-MAR-2024, entry version 131.
DE   SubName: Full=Sll0267 protein {ECO:0000313|EMBL:BAA18497.1};
GN   OrderedLocusNames=sll0267 {ECO:0000313|EMBL:BAA18497.1};
OS   Synechocystis sp. (strain PCC 6803 / Kazusa).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales; Merismopediaceae;
OC   Synechocystis.
OX   NCBI_TaxID=1111708 {ECO:0000313|EMBL:BAA18497.1, ECO:0000313|Proteomes:UP000001425};
RN   [1] {ECO:0000313|EMBL:BAA18497.1, ECO:0000313|Proteomes:UP000001425}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6803 / Kazusa {ECO:0000313|Proteomes:UP000001425};
RX   PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA   Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA   Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT   genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
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DR   EMBL; BA000022; BAA18497.1; -; Genomic_DNA.
DR   PIR; S76238; S76238.
DR   IntAct; P74400; 4.
DR   STRING; 1148.gene:10499378; -.
DR   PaxDb; 1148-1653584; -.
DR   EnsemblBacteria; BAA18497; BAA18497; BAA18497.
DR   KEGG; syn:sll0267; -.
DR   eggNOG; COG2203; Bacteria.
DR   eggNOG; COG3614; Bacteria.
DR   eggNOG; COG5001; Bacteria.
DR   InParanoid; P74400; -.
DR   PhylomeDB; P74400; -.
DR   Proteomes; UP000001425; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProt.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 2.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.30.450.350; CHASE domain; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR006189; CHASE_dom.
DR   InterPro; IPR042240; CHASE_sf.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013655; PAS_fold_3.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00229; sensory_box; 2.
DR   PANTHER; PTHR46663; DIGUANYLATE CYCLASE DGCT-RELATED; 1.
DR   PANTHER; PTHR46663:SF2; GGDEF DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF03924; CHASE; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF13185; GAF_2; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF08447; PAS_3; 1.
DR   Pfam; PF13426; PAS_9; 1.
DR   SMART; SM01079; CHASE; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00065; GAF; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00086; PAC; 2.
DR   SMART; SM00091; PAS; 2.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR   PROSITE; PS50839; CHASE; 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50113; PAC; 2.
DR   PROSITE; PS50112; PAS; 2.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001425};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        202..221
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        241..258
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        540..562
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          302..494
FT                   /note="CHASE"
FT                   /evidence="ECO:0000259|PROSITE:PS50839"
FT   DOMAIN          710..752
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          782..837
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          1019..1091
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          1095..1148
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          1180..1318
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          1327..1578
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
FT   COILED          1002..1029
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1578 AA;  178548 MW;  BE1604B60FB456DF CRC64;
     MSIMPPPPSS VPPHQGHGFW RGAVLLVLIF LIIFGGVAVA HWRIEMVSQQ MRQQLLSQVE
     MVSLNLNFRL FQELSFTPQD LENPSFQRLH NQMAAYAQTF EHRSIYTMVI RSGKILFGPD
     SLKSGDFLAR DPGAVYKNPP EAVRQLFELP SKKLVIGPYH SERGNFVSAY APILQPQSER
     VLVIVAMDME ARQWHQKLQQ KLWTPLLFSV GLIALILGGD YLLQERRRWR NSFITNQGEA
     LATAIVGLFL TLALTAVVQE NSLLNSQRNF SQLAIPRANL FAQKLWELQN YGLSSLNSFM
     ESSAEVTRAE FARFTLPMIR KLSIQAWEWI PKVTAADREN FERRARQDGI ENFQIFELNR
     RGKPVPAEGR EVYYPIFYAE PLAGNDIALG FDVSSNESAK MALDEALENR LPTATNPLTL
     IQELGKQRGI VAYSPVFADG NLENPPMGVA AVVLRLNDFL TQTFGEISFG DKSLELQWLQ
     LSVDRSPLVL ASSAPSPFSM NNWQSNKELF QVYPLFIFGR AYALLLWPGP EFNQNYPKQM
     AMVAFGVGTG ITVLVTIIVA IITNSQANLT HQIRQRTKEL RATLGQLRER VKEMDCLVAI
     AQMGQQADLV LEEFLQNTVD LLPLAFRYEK LASARLTWGN SIYQSPNYQK TDYCLIAEFQ
     TEHFHRGQLE VCYGEERDFL PEEKALLNTV SQFLSRFLES HYTEIILERN ERNYREIFNS
     THEAIFIQDA HQATVLDVNQ PMLTMYGYGN KEEVIGRPIG DFSADKPGKT EAEIEQKLRQ
     ARNAEPQMFE WLAKKQDGSL FWAEVSIQPT VIDGKSRLLA VVRDISERKQ NQQRIEYLSR
     LYATLSQVNR AIIENRERDD LFRAICDVGV AVGQFSLIWF GLIDPDRQTI IPYMAGGHTT
     AYLENIRITF KDEPAGRGPT GTAAREGRLV ICSNISQDPK MAPWRGSAMR YGFLSSAAVP
     IRQGGQVVAV LTFYSQEAGF FSEDEQDLLQ EISDNLSFAL DAIQLDQANQ RAQNQLGENE
     ERLRLALEAA NQGFYDLNLQ TGQAVVSPQY GQILGYDPQY FQETEQRWLE RIHPQDQQRV
     REIYDQYIQG KIPRYAVECR QRTMAGQWKW LLSLGKIVEW DSQGKPLRML GILTDVTERK
     QAEAQIENLA YYDPLTALPN RRLLLDRAEN ALALAQRSKH FGAIVLIDLD GFKTLNDARG
     HDSGDRLLQM VAKRLADSLR DSDTVARLGG DEFIVLLPEL AHDRELAARL GLGVGEKIRQ
     ALATPFTLEA EQVQISGSIG ITLFPKLNEK VSDLFKEADT AMYQAKKAGR DKVCLFESQM
     QLEVESRFAL EADLRSALEQ KQFQVYLQPQ VDSHGVWIGA EALLRWNHPG RGFIPPNIFI
     PIAEEIGLIG GIGDFVLEQV CQYLARLQQL GLTLRIAINV SPRQFRQANF AKEIKNLLAC
     TGVDPYRLTL EVTEGLIVED THQAIATMFE LQTLGIHFSV DDFGTGYSSL SYLKRLPLNE
     LKIDRAFVQD APQDLNNAAL VEAIISVART FNLAIVAEGV ETEEQVQFLA QLGCNFYQGY
     FYGRPMPIDE FHQKLTAS
//