ID   NUSB_SYNY3              Reviewed;         221 AA.
AC   P74395;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2002, sequence version 2.
DT   27-MAR-2024, entry version 135.
DE   RecName: Full=Transcription antitermination protein NusB {ECO:0000255|HAMAP-Rule:MF_00073};
DE   AltName: Full=Antitermination factor NusB {ECO:0000255|HAMAP-Rule:MF_00073};
GN   Name=nusB {ECO:0000255|HAMAP-Rule:MF_00073};
GN   OrderedLocusNames=sll0271;
OS   Synechocystis sp. (strain PCC 6803 / Kazusa).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales; Merismopediaceae;
OC   Synechocystis.
OX   NCBI_TaxID=1111708;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6803 / Kazusa;
RX   PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA   Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA   Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT   genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
CC   -!- FUNCTION: Involved in transcription antitermination. Required for
CC       transcription of ribosomal RNA (rRNA) genes. Binds specifically to the
CC       boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
CC       {ECO:0000255|HAMAP-Rule:MF_00073}.
CC   -!- SIMILARITY: Belongs to the NusB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00073, ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAA18492.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; BA000022; BAA18492.1; ALT_INIT; Genomic_DNA.
DR   PIR; S76233; S76233.
DR   AlphaFoldDB; P74395; -.
DR   SMR; P74395; -.
DR   IntAct; P74395; 1.
DR   STRING; 1148.gene:10499373; -.
DR   PaxDb; 1148-1653579; -.
DR   EnsemblBacteria; BAA18492; BAA18492; BAA18492.
DR   KEGG; syn:sll0271; -.
DR   eggNOG; COG0781; Bacteria.
DR   InParanoid; P74395; -.
DR   PhylomeDB; P74395; -.
DR   Proteomes; UP000001425; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006353; P:DNA-templated transcription termination; IEA:UniProtKB-UniRule.
DR   GO; GO:0031564; P:transcription antitermination; IEA:UniProtKB-KW.
DR   CDD; cd00619; Terminator_NusB; 1.
DR   Gene3D; 1.10.940.10; NusB-like; 1.
DR   HAMAP; MF_00073; NusB; 1.
DR   InterPro; IPR035926; NusB-like_sf.
DR   InterPro; IPR011605; NusB_fam.
DR   InterPro; IPR006027; NusB_RsmB_TIM44.
DR   NCBIfam; TIGR01951; nusB; 1.
DR   PANTHER; PTHR11078:SF3; ANTITERMINATION NUSB DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR11078; N UTILIZATION SUBSTANCE PROTEIN B-RELATED; 1.
DR   Pfam; PF01029; NusB; 1.
DR   SUPFAM; SSF48013; NusB-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome; RNA-binding; Transcription;
KW   Transcription antitermination; Transcription regulation.
FT   CHAIN           1..221
FT                   /note="Transcription antitermination protein NusB"
FT                   /id="PRO_0000176598"
SQ   SEQUENCE   221 AA;  24740 MW;  6F6C1211E8D1D644 CRC64;
     MLARQQPRRV ARELSLLSLS QLSRKDTKPE TLEQGDLEAL LLAATRTLSG EVHEILETAS
     AELSRSHERL LNSEIRASNL NSAKAMLEEA MTLTETVINR LALAVDLPET LQLAGQMEVR
     KFALELIGTV CRRRQQIDEQ LQEAMVDWQL SRLAKIDQDI LRLAIAELDY LGVPQKVAIN
     EAVELAKRYS GQDGHRFING VLRRVTEKKT DGAPVTPGEP R
//