P74386 (URE2_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Urease subunit beta
EC=3.5.1.5

Alternative name(s):
Urea amidohydrolase subunit beta

Gene names

Name:	ureB
Ordered Locus Names:	sll0420

Organism

Synechocystis sp. (strain PCC 6803 / Kazusa)

Taxonomic identifier

1111708 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Synechocystis

Protein attributes

Sequence length	105 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Urea + H2O = CO2 + 2 NH3. HAMAP MF_01954
Pathway	Nitrogen metabolism; urea degradation; CO(2) and NH(3) from urea (urease route): step 1/1. HAMAP MF_01954
Subunit structure	Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme By similarity.
Subcellular location	Cytoplasm By similarity HAMAP MF_01954.
Sequence similarities	Belongs to the urease beta subunit family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nickel cation binding Inferred from electronic annotation. Source: InterPro urease activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 105	105	Urease subunit beta HAMAP MF_01954		PRO_0000067597

Sequences

	Sequence		Length	Mass (Da)
	P74386 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 391BE6DA40B047DE	FASTA	105	11,382
	10 20 30 40 50 60 MATMIPGEII TPEGDIELNV GRSTCTINVA NTGDRPIQVG SHYHFYEVNA ALQFDRDLAK 70 80 90 100 GMRLDIPAGT AVRFEPGDEK NVNLVAYAGS REIYGFNGLV NGPLE

References

[1]

"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed: 8905231] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27184 / PCC 6803 / N-1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000022 Genomic DNA. Translation: BAA18483.1.
PIR	S76224.
RefSeq	NP_441805.1. NC_000911.1.
3D structure databases
ProteinModelPortal	P74386.
SMR	P74386. Positions 4-104.
ModBase	Search...
Protein-protein interaction databases
STRING	P74386.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	952908.
GenomeReviews	Gene locus sll0420 in contig BA000022_GR.
KEGG	syn:sll0420.
NMPDR	fig|1148.1.peg.1906.
PATRIC	23841112. VBISynSp132158_2107.
Phylogenomic databases
eggNOG	COG0832.
HOGENOM	HBG365918.
OMA	PLSGKRE.
PhylomeDB	P74386.
ProtClustDB	PRK13203.
Enzyme and pathway databases
BioCyc	SSP1148:SLL0420-MONOMER.
Family and domain databases
HAMAP	MF_01954. Urease_beta. [Tree]
InterPro	IPR002019. Urease_beta. [Graphical view]
Gene3D	G3DSA:2.10.150.10. Urease_beta. 1 hit.
KO	K01429.
Pfam	PF00699. Urease_beta. 1 hit. [Graphical view]
SUPFAM	SSF51278. Urease_beta. 1 hit.
TIGRFAMs	TIGR00192. Urease_beta. 1 hit.
ProtoNet	Search...

Entry information

Entry name

URE2_SYNY3

Accession

Primary (citable) accession number: P74386

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	February 1, 1997
Last modified:	January 25, 2012
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program